Mastering Calcium Channel Blockers
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Questions and Answers

Which of the following statements about calcium influx in ischemia is true?

  • Calcium influx is not related to ATP-consuming enzyme activity
  • Calcium influx is decreased in ischemia
  • Calcium influx is not affected by hypoxia
  • Calcium influx is increased due to hypoxia-induced membrane depolarization (correct)

    • What is the role of calcium channel blockers in protecting the tissue during ischemia?

  • They promote the activity of ATP-consuming enzymes
  • They increase the entrance of calcium into cardiac and smooth muscle cells
  • They inhibit the entrance of calcium into cardiac and smooth muscle cells (correct)
  • They deplete energy stores in the tissue

    • How does increased calcium influx worsen ischemia?

  • By decreasing membrane depolarization
  • By depleting energy stores in the tissue
  • By inhibiting the entrance of calcium into cardiac and smooth muscle cells
  • By promoting the activity of ATP-consuming enzymes (correct)

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