42 Questions
Which of the following is a characteristic of calcium channel blockers (CCBs) on cardiac muscle?
Decrease AV node conduction
Which type of calcium channel blockers (CCBs) may cause a baroreceptor-mediated tachycardia?
Dihydropyridines
Which type of smooth muscle is more sensitive to calcium channel blockers (CCBs)?
Arterial smooth muscle
Which type of CCBs cause constipation and have many drug interactions?
Non-dihydropyridine CCBs
Which drug can cause Systemic Lupus Erythematosus (SLE)?
Hydralazine
Which drug promotes hair growth?
Minoxidil
Which of the following is NOT a symptom of toxicity of Nitroprusside?
Hypotension
Which of the following is the correct onset and duration of action for Nitroglycerin spray?
Onset 2 min, Duration 25 min
Which enzyme is most important for the activation of Nitroglycerin?
Aldehyde dehydrogenase isoform 2 (ALDH2)
Which of the following is a potential mechanism for the development of tolerance to Nitroglycerin?
Systemic compensation
Which of the following is a characteristic of all oral calcium channel blockers (CCBs)?
They come in long-acting products
Which of the following adverse effects is associated with non-dihydropyridine CCBs?
Gingival hyperplasia
Which of the following drugs is a potent arteriolar vasodilator and often coadministered with beta-blockers to prevent reflex tachycardia?
Hydralazine
Which of the following is a common adverse effect of minoxidil?
Peripheral edema
Which of the following is a characteristic of dihydropyridine calcium channel blockers (CCBs)?
They cause a baroreceptor-mediated tachycardia
Which type of smooth muscle is more sensitive to calcium channel blockers (CCBs)?
Arterial smooth muscle
Which of the following is a characteristic of non-dihydropyridine calcium channel blockers (CCBs)?
They slow AV conduction
Which of the following calcium channel blockers (CCBs) causes peripheral edema and gastroesophageal reflux disease (GERD)?
Nifedipine
Which of the following drugs is associated with thiocyanate poisoning?
Nitroprusside
Which of the following calcium channel blockers (CCBs) is commonly coadministered with beta-blockers to prevent reflex tachycardia?
Nifedipine
Which of the following calcium channel blockers (CCBs) is available in both oral and IV formulations?
Nicardipine
Which of the following adverse effects is associated with dihydropyridine CCBs?
Peripheral edema
Which of the following drugs is a substrate and inhibitor of 3A4 enzyme?
Verapamil
Which of the following drugs is a potent arteriolar vasodilator and may cause hypertrichosis?
Minoxidil
Which of the following drugs is a non-selective vasodilator that dilates both arterial and venous vessels?
Nitroprusside
Which of the following drugs does NOT develop tolerance unlike nitroglycerin?
Nitroprusside
Which of the following drugs causes only a modest increase in heart rate with a net decrease in myocardial oxygen consumption?
Nitroprusside
Which of the following enzymes is most important for the activation of nitroglycerin?
Aldehyde dehydrogenase isoform 2 (ALDH2)
Which of the following drugs is commonly coadministered with beta-blockers to prevent reflex tachycardia?
Nifedipine
Which type of calcium channel blockers (CCBs) cause constipation and have many drug interactions?
Non-dihydropyridine CCBs
Which of the following drugs is a potent arteriolar vasodilator and may cause hypertrichosis?
Minoxidil
Which of the following is a characteristic of dihydropyridine calcium channel blockers (CCBs)?
They have a greater effect on arterial smooth muscle than venous smooth muscle.
Which of the following calcium channel blockers (CCBs) causes peripheral edema and gastroesophageal reflux disease (GERD)?
Nifedipine
Which type of smooth muscle is more sensitive to calcium channel blockers (CCBs) than bronchiolar, GI, and uterine smooth muscle?
Arterial smooth muscle
Which of the following drugs is a non-selective vasodilator that dilates both arterial and venous vessels?
Nitroprusside
Which of the following drugs does NOT develop tolerance unlike nitroglycerin?
Nitroprusside
Which enzyme is most important for the activation of Nitroglycerin?
Aldehyde dehydrogenase isoform 2 (ALDH2)
Which of the following adverse effects is associated with non-dihydropyridine CCBs?
Peripheral edema
Which of the following drugs directly acts on the vasculature by releasing nitric oxide (NO)?
Nitroprusside
Which of the following calcium channel blockers (CCBs) is commonly coadministered with beta-blockers to prevent reflex tachycardia?
Verapamil
Which of the following drugs is a potent arteriolar vasodilator and may cause hypertrichosis?
Minoxidil
Which of the following adverse effects is associated with non-dihydropyridine calcium channel blockers (CCBs)?
Peripheral edema
Test your knowledge on the pharmacokinetics, indications, and toxicity of nitroprusside, a non-selective vasodilator that dilates both arterial and venous vessels. Learn about its unique properties, including the absence of tolerance development and a modest increase in heart rate. Explore its indications and potential toxicity.
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