26 Questions
Which of the following is a characteristic of adult onset immune thrombocytopenic purpura (ITP)?
It tends to lead to chronic disease
Which of the following is a potential cause of clotting disorders?
Ebola
Which of the following is a characteristic of Marburg virus?
It has a fatality rate of 90%
Which of the following laboratory tests is used to evaluate hemostasis?
CBC - Platelet count
Which of the following blood products is used for anemic patients?
RBC
Which of the following is a function of blood vessels and platelets in controlling bleeding?
To stop flow rapidly when the system is compromised
What is primary hemostasis?
The accumulation and adherence of platelets to the injury area
What are the coagulation factors involved in secondary hemostasis?
Proteins and factors (Ca ions) in blood
What is the clotting cascade?
The series of reactions that lead to the formation of a blood clot
How can clotting be stopped using drug therapy?
By disrupting the clotting cascade
What are the most common clinically significant disturbances of hemostasis?
Adequate numbers of platelets and normal amounts of coagulation factors
What is the average survival of platelets in the circulation?
10 days
What is the term used to describe small red or red-blue spots about 1-5 mm in diameter?
Petechiae
Which of the following drugs blocks thromboxane synthesis?
NSAIDS
Which of the following is a cause of coagulation disturbance?
Inadequate absorption of vitamin K
What is the net effect of disseminated intravascular coagulation (DIC)?
Widespread failure of hemostasis
Which condition is characterized by the formation of large VWF multimer chains that criss-cross blood vessels and are hyper adhesive to platelets?
Thrombotic Thrombocytopenic Purpura (TTP)
What is the treatment for TTP
Plasma exchange
Which of the following is a cause of thromboplastic material liberation into circulation?
All of the above
What can inadequate synthesis of vitamin K lead to?
Inadequate absorption of vitamin K
Which pathway is responsible for the slow, 1-6 minutes maintenance of the blood coagulation factors?
Intrinsic pathway
Which pathway is responsible for the fast, 10-15 seconds, explosive emergency response of the blood coagulation factors?
Extrinsic pathway
What is the goal of both the intrinsic and extrinsic pathways of the blood coagulation factors?
To form fibrin
What is the role of thrombin in the blood coagulation process?
To convert prothrombin into thrombin
What is the function of the fibrinolytic system in the blood coagulation process?
To dissolve clots by breaking down fibrin
What is the role of antithrombin III in the blood coagulation process?
To inhibit factor 2a in the cascade
Test your knowledge on blood clotting factors and pathways in this quiz. Explore the intrinsic and extrinsic pathways, as well as the intricate chain reaction involved in maintaining homeostasis.
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