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Mass Spectrometry Imaging (MSI) Quiz

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Questions and Answers

What is the main purpose of mass spectrometry imaging (MSI)?

To identify the atomic composition of molecules in a sample
To quantify the absolute abundance of molecules in a sample
To visualize the spatial distribution of molecules based on their molecular masses (correct)
To measure the concentration of molecules in a sample

How is mass spectrometry imaging (MSI) performed?

By using a microscope to visualize the sample
By analyzing the color distribution of the sample
By measuring the volume of the sample
By collecting a mass spectrum at different spots as the sample is moved (correct)

What does the mass spectrum collected during mass spectrometry imaging (MSI) help to map?

The physical state of the sample
The absolute quantity of each compound in the sample
The spatial distribution of a compound pixel by pixel (correct)
The chemical structure of the compounds in the sample

What type of data does mass spectrometry imaging (MSI) generate?

Pictures of the spatially resolved distribution of compounds (D) Signup and view all the answers

What is the signal generated by mass spectrometry imaging (MSI) proportional to?

The relative abundance of the compound (C) Signup and view all the answers

What was the first definition of proteomics?

Large-scale analysis of gene products involving only proteins (C) Signup and view all the answers

What is the aim of proteomics?

To identify all the proteins in a cell and create a complete 3-D map of the cell (B) Signup and view all the answers

What does the more inclusive definition of proteomics combine protein studies with?

Genomics and yeast two-hybrid analysis (A) Signup and view all the answers

What is the goal of proteomics?

To obtain a more global and integrated view of biology by studying all the proteins of a cell (A) Signup and view all the answers

What does proteomics aim to create a complete three-dimensional (3-D) map of?

The cell indicating where proteins are located (C) Signup and view all the answers