Manual Sequence Alignment in Bioinformatics
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Questions and Answers

What are two scoring matrices used in dynamic programming methods?

  • BLOSUM and FASTA
  • PAM and BLOSUM (correct)
  • Dayhoff and Henikoff
  • PAM and BLAST

    • Which scoring matrix was developed by Henikoff & Henikoff in 1992?

  • Dayhoff
  • FASTA
  • PAM
  • BLOSUM (correct)

    • What is the main purpose of sequence alignments in bioinformatics?

  • Creating synthetic organisms
  • Identifying genetic mutations
  • Producing phylogenetic trees (correct)
  • Developing vaccines

    • In large-scale database searches, what is a key feature of word methods?

    <p>They are more efficient than dynamic programming</p> Signup and view all the answers

    What does the term 'k-tuple methods' refer to?

    <p>Heuristic methods</p> Signup and view all the answers

    What is the main advantage of word methods in database searches?

    <p>They match short, nonoverlapping subsequences efficiently</p> Signup and view all the answers

    'Convergent evolution' refers to a situation where proteins...

    <p>Are evolutionarily unrelated but have similar structures</p> Signup and view all the answers

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