Questions and Answers
What is the purpose of global alignment?
To compare sequences of similar sizes
What is the purpose of local alignment?
To find shared subsequences
In simple alignment, what does a 'gap' represent in the scoring scheme?
A deletion
What solution is recommended for the limitation of exponential alignments between two sequences?
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What does the optimal alignment of two similar sequences aim to maximize and minimize?
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In global sequence alignment, what is the purpose of considering the 'best' path for each cell in the matrix?
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What does a positive value in the substitution/match matrix indicate during sequence alignment?
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How is the quality of an alignment affected by increasing gap penalties?
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Which algorithm is known as Needleman-Wunsch algorithm?
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In local sequence alignment, what is the primary objective?
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