12 Questions
What is the primary purpose of BLAST?
Analyzing biological sequence data
Who introduced the Basic Local Alignment Search Tool (BLAST)?
Stephen Altschul
What does BLAST help identify?
Members of gene families
Why is BLAST considered a crucial tool in bioinformatics?
It helps infer functional and evolutionary relationships between sequences
Which aspect has BLAST continuously updated for improvement?
Speed and accuracy
How many types of BLAST variants exist based on the type of sequence?
Five types
What type of comparison does BLASTN perform?
Nucleotide query sequence to a nucleotide sequence database
Which BLAST program compares a protein query sequence to a protein sequence database?
BLASTP
What does TBLASTN do when comparing a protein query sequence to a nucleotide sequence database?
Translates the nucleotide sequences into six reading frames
How is the expect value (E-value) used in BLAST searches?
To limit the number of hits to significant ones
What does an E-value of 10e-10 < E-value < 10e-50 indicate in BLAST searches?
Closely related sequences
When does an E-value greater than 1 indicate in BLAST searches?
Unrelated proteins
Learn about the Basic Local Alignment Search Tool (BLAST) widely used in bioinformatics to analyze DNA and protein sequences. Discover how BLAST efficiently identifies sequence similarities and find out about its importance in studying genetic data.
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