Manifestations of Fabry Disease

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Questions and Answers

Which of the following is a feature of the condition?

  • Dermatological abnormalities
  • Hepatosplenomegaly (correct)
  • Respiratory distress
  • Gastrointestinal bleeding

What type of lesions are associated with the heart in this condition?

  • Lesions of heart valves (correct)
  • Valvular vegetations
  • Ventricular aneurysms
  • Atrial septal defects

In which arteries can subendothelial deposits be found in this condition?

  • Renal arteries
  • Coronary arteries (correct)
  • Pulmonary arteries
  • Cerebral arteries

Which of the following is NOT a feature of the condition?

<p>Gastrointestinal abnormalities (D)</p> Signup and view all the answers

What is a common finding in the brain in this condition?

<p>Lesions in the brain (B)</p> Signup and view all the answers

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Study Notes

Clinical Features

  • Hepatosplenomegaly: Enlargement of both liver and spleen
  • Skeletal deformities: Abnormalities in bone structure and growth
  • Lesions of heart valves: Damage to heart valves, affecting blood flow and heart function
  • Subendothelial arterial deposit: Abnormal accumulation of substances in the coronary arteries, leading to cardiovascular issues
  • Lesions in the brain: Damage or abnormality in brain tissue, potentially affecting cognitive and motor function

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