18 Questions
What is the main biological basis for the manifestation of epilepsy?
Imbalance of excitatory/inhibitory neurotransmission
Which neurotransmitter is NOT implicated in the biological basis of epilepsy?
Dopamine
In epilepsy, epileptogenesis occurs when:
The threshold for firing is reduced beyond the capability of regulatory mechanisms to prevent firing
What is the second most common neurologic disorder after stroke?
Epilepsy
What is the role of voltage gated cation channels (Na+) in the neurochemical basis of epilepsy?
They contribute to epileptogenesis when firing threshold is reduced
Which neurotransmitter imbalance is a key factor in the manifestation of epilepsy?
Glutamate-GABA imbalance
What distinguishes epilepsy from seizures?
Epilepsy is a heterogeneous symptom complex.
Which statement best describes the pharmacological management of epilepsy?
Pharmacological management focuses on preventing recurrent seizures.
What is the main purpose of identifying limitations in certain drug treatments for epilepsy?
To improve the clinical uses of antiepileptic drugs.
Which main drug group is commonly used in the pharmacological management of epilepsy?
Antiepileptic drugs
Why is it important for healthcare professionals to understand the causes of seizures in epilepsy?
To prevent potential triggers for seizure activity.
What is the significance of the International Epilepsy Day 2024?
Raising global awareness about epilepsy and supporting individuals with epilepsy.
Which brain region exhibits asynchronous firing in EEG recordings from epilepsy patients?
Temporal lobes
What is the main mechanism of action of Benzodiazepines in the treatment of epilepsy?
Binding to GABA receptors at an allosteric site
Which antiepileptic drug modulates GABA metabolism?
Vigabatrin
Loss of consciousness during an epileptic seizure is associated with abnormalities in which brain region?
Reticular formation
Which type of attack in epilepsy can be either localized or generalized?
Partial
Which cation channel modulation is associated with Ethosuximide and Valproate in the treatment of epilepsy?
Ca++ T-type channels
Learn about the manifestations of epilepsy through EEG readings, including asynchronous high frequency firing and regular oscillatory patterns. Explore the prevalence of epilepsy and its psychiatric comorbidities, with a focus on the statistics in Ireland.
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