Podcast
Questions and Answers
Which of the following is a characteristic feature of Alzheimer's disease?
Which of the following is a characteristic feature of Alzheimer's disease?
- Plaques
- Tangles
- Both plaques and tangles (correct)
- None of the above
Which of the following is NOT a treatment option for Alzheimer's disease?
Which of the following is NOT a treatment option for Alzheimer's disease?
- Memantine
- Tacrine
- Rivastigmine
- Aducanumab (correct)
What is the cause of Alzheimer's disease?
What is the cause of Alzheimer's disease?
- Genetics
- Environmental factors
- Combination of inter-related factors (correct)
- All of the above
What did Dr. Alzheimer observe in his patient, Auguste Deter?
What did Dr. Alzheimer observe in his patient, Auguste Deter?
When did researchers identify the b-amyloid protein as a factor in Alzheimer's disease?
When did researchers identify the b-amyloid protein as a factor in Alzheimer's disease?
What did British pathologists determine about Alzheimer's disease in the 1960s?
What did British pathologists determine about Alzheimer's disease in the 1960s?
What did Dr. Alzheimer find in Auguste Deter's brain tissue after her death?
What did Dr. Alzheimer find in Auguste Deter's brain tissue after her death?
Which of the following is a symptom of Alzheimer's disease?
Which of the following is a symptom of Alzheimer's disease?
Which stage of Alzheimer's disease is characterized by a loss of ability to manage instrumental activities of daily life?
Which stage of Alzheimer's disease is characterized by a loss of ability to manage instrumental activities of daily life?
What happens to the cortex in the brain of a person with Alzheimer's disease?
What happens to the cortex in the brain of a person with Alzheimer's disease?
What are amyloid plaques and tangles in the brain?
What are amyloid plaques and tangles in the brain?
What is the role of acetylcholine in the brain?
What is the role of acetylcholine in the brain?
What happens to the nucleus basalis in Alzheimer's disease?
What happens to the nucleus basalis in Alzheimer's disease?
What is the impact of loss of acetylcholine in Alzheimer's disease?
What is the impact of loss of acetylcholine in Alzheimer's disease?
Which of the following is true about cholinergic therapy in Alzheimer's Disease?
Which of the following is true about cholinergic therapy in Alzheimer's Disease?
Which category of drugs is used to treat cognitive symptoms of Alzheimer's Disease?
Which category of drugs is used to treat cognitive symptoms of Alzheimer's Disease?
Which of the following drugs is NOT a cholinesterase inhibitor?
Which of the following drugs is NOT a cholinesterase inhibitor?
Which drug has the longest half-life among the cholinesterase inhibitors?
Which drug has the longest half-life among the cholinesterase inhibitors?
Which drug has been discontinued in the US due to safety concerns?
Which drug has been discontinued in the US due to safety concerns?
Which drug has the lowest oral bioavailability among the cholinesterase inhibitors?
Which drug has the lowest oral bioavailability among the cholinesterase inhibitors?
Which drug has a dual mechanism of action, including competitive inhibition of AChE and allosteric modulation of nicotinic receptors?
Which drug has a dual mechanism of action, including competitive inhibition of AChE and allosteric modulation of nicotinic receptors?
Which of the following drugs has the longest half-life?
Which of the following drugs has the longest half-life?
What is the oral bioavailability range of Galantamine?
What is the oral bioavailability range of Galantamine?
Which drug is associated with liver toxicity as a side effect?
Which drug is associated with liver toxicity as a side effect?
Which drug is available in an extended-release once-a-day tablet?
Which drug is available in an extended-release once-a-day tablet?
Which drug is metabolized hepatically by Cytochrome P450?
Which drug is metabolized hepatically by Cytochrome P450?
Which drug is associated with less frequent gastrointestinal effects when delivered through a patch?
Which drug is associated with less frequent gastrointestinal effects when delivered through a patch?
Which drug has a dual mechanism of action involving nicotinic receptors and acetylcholine?
Which drug has a dual mechanism of action involving nicotinic receptors and acetylcholine?
Which drug is an amyloid beta-directed antibody?
Which drug is an amyloid beta-directed antibody?
Which drug has been controversially approved under the accelerated approval pathway?
Which drug has been controversially approved under the accelerated approval pathway?
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