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Which disease is characterized by gait ataxia, hand clumsiness, dysarthria, pes cavus, and kyphoscoliosis, with high incidence of cardiac disease and diabetes?
Which disease is characterized by gait ataxia, hand clumsiness, dysarthria, pes cavus, and kyphoscoliosis, with high incidence of cardiac disease and diabetes?
In which of the following diseases does cognitive changes such as memory disturbances, behavior, and language issues lead to dementia and may manifest as Alzheimer's disease or frontotemporal dementia?
In which of the following diseases does cognitive changes such as memory disturbances, behavior, and language issues lead to dementia and may manifest as Alzheimer's disease or frontotemporal dementia?
Which disease affects the cerebellar cortex, spinal cord, and other brain regions variably, leading to ataxia?
Which disease affects the cerebellar cortex, spinal cord, and other brain regions variably, leading to ataxia?
Which disease is characterized by difficulty swallowing, respiratory issues, and muscle weakness due to involvement of the motor system?
Which disease is characterized by difficulty swallowing, respiratory issues, and muscle weakness due to involvement of the motor system?
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Which genetic abnormality involving GAA trinucleotide repeat expansion is associated with Frataxin protein and regulation of mitochondrial iron?
Which genetic abnormality involving GAA trinucleotide repeat expansion is associated with Frataxin protein and regulation of mitochondrial iron?
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What disease is caused by CAG repeat expansions and involves intranuclear inclusions, among other mutations?
What disease is caused by CAG repeat expansions and involves intranuclear inclusions, among other mutations?
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What is the primary cause of mitochondrial dysfunction in Friedreich's ataxia?
What is the primary cause of mitochondrial dysfunction in Friedreich's ataxia?
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Which of the following is a characteristic feature of amyotrophic lateral sclerosis (ALS)?
Which of the following is a characteristic feature of amyotrophic lateral sclerosis (ALS)?
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Which gene mutation is most commonly associated with familial forms of amyotrophic lateral sclerosis (ALS)?
Which gene mutation is most commonly associated with familial forms of amyotrophic lateral sclerosis (ALS)?
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Which of the following is a characteristic feature of Friedreich's ataxia?
Which of the following is a characteristic feature of Friedreich's ataxia?
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Which of the following is a common feature of both amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD)?
Which of the following is a common feature of both amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD)?
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Which of the following is a characteristic feature of ataxia telangiectasia?
Which of the following is a characteristic feature of ataxia telangiectasia?
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Which of the following is a characteristic feature of amyotrophic lateral sclerosis (ALS)?
Which of the following is a characteristic feature of amyotrophic lateral sclerosis (ALS)?
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Which of the following ataxias is associated with a deficiency in frataxin protein?
Which of the following ataxias is associated with a deficiency in frataxin protein?
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In amyotrophic lateral sclerosis (ALS), which of the following is typically spared?
In amyotrophic lateral sclerosis (ALS), which of the following is typically spared?
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Which of the following is a characteristic feature of ataxia telangiectasia?
Which of the following is a characteristic feature of ataxia telangiectasia?
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Which of the following is a common cause of cerebellar ataxia due to thiamine deficiency?
Which of the following is a common cause of cerebellar ataxia due to thiamine deficiency?
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In spinocerebellar ataxias, which of the following is commonly observed?
In spinocerebellar ataxias, which of the following is commonly observed?
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