Management of Diabetes: Non-Insulin Therapies Quiz
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Questions and Answers

What is the fasting plasma glucose (FPG) range for diagnosing Type 2 Diabetes Mellitus (T2DM)?

  • 100-125 mg/dL (correct)
  • 120-140 mg/dL
  • 90-110 mg/dL
  • 130-150 mg/dL

What is the HbA1c level that indicates prediabetes?

  • 5.7% (correct)
  • 6.5%
  • 4.9%
  • 6.0%

Which postprandial oral glucose tolerance test result indicates Type 2 Diabetes Mellitus (T2DM)?

  • 200-250 mg/dL (correct)
  • 250-300 mg/dL
  • 100-120 mg/dL
  • 140-199 mg/dL

What is a limitation of using HbA1c for diagnosing diabetes?

<p>It is not affected by conditions that may shorten the lifespan of red blood cells (B)</p> Signup and view all the answers

To minimize hypoglycemia and weight gain in Type 2 Diabetes Mellitus (T2DM) patients, which class of medications like Empagliflozin belong to?

<p>SGLT2 inhibitors (A)</p> Signup and view all the answers

What is the typical decrease in A1c when using SGLT2-i as monotherapy?

<p>~0.5-1% (C)</p> Signup and view all the answers

Which of the following SGLT2-i has the maximum daily dose that depends on GFR?

<p>Canagliflozin (Invokana®) (B)</p> Signup and view all the answers

Which class of medication should be avoided in combination with DPP4i for T2DM treatment?

<p>GLP1 RA (C)</p> Signup and view all the answers

Which medication class is most effective for minimizing weight gain or promoting weight loss in T2DM treatment?

<p>GLP1 RA (A)</p> Signup and view all the answers

Which medication class should be considered first for minimizing cost in T2DM treatment?

<p>SU (C)</p> Signup and view all the answers

What is the recommended HbA1c level for diagnosing type 2 diabetes mellitus (T2DM)?

<p>6.5% or higher (C)</p> Signup and view all the answers

What are the limitations of using HbA1c for diagnosing T2DM?

<p>It does not provide information about daily blood glucose fluctuations (B)</p> Signup and view all the answers

Which class of medications for T2DM has been shown to have cardiovascular benefits?

<p>SGLT2 inhibitors (A)</p> Signup and view all the answers

What are the primary treatment goals for T2DM?

<p>Reducing the risk of complications and improving quality of life (D)</p> Signup and view all the answers

How can hypoglycemia and weight gain be minimized in the treatment of T2DM?

<p>By prescribing medications that cause weight loss and have a low risk of hypoglycemia (C)</p> Signup and view all the answers

What is the main diagnostic criterion for Type 2 Diabetes Mellitus (T2DM)?

<p>Hemoglobin A1c (HbA1c) level (A)</p> Signup and view all the answers

Which of the following is NOT a limitation of using HbA1c for diabetes management?

<p>HbA1c testing is expensive and time-consuming (B)</p> Signup and view all the answers

Which class of medications for T2DM primarily targets the kidneys to reduce glucose levels in the blood?

<p>Sodium glucose cotransporter 2 inhibitors (SGLT2i) (A)</p> Signup and view all the answers

What is the primary treatment goal for T2DM, according to the American Diabetes Association (ADA)?

<p>Reduce the risk of long-term complications (A)</p> Signup and view all the answers

Which of the following strategies can help minimize hypoglycemia and weight gain in T2DM patients?

<p>Combining lifestyle changes with medication (C)</p> Signup and view all the answers

What should be avoided combining with DPP4 inhibitors for Type 2 Diabetes Mellitus (T2DM) treatment?

<p>GLP1 receptor agonists (D)</p> Signup and view all the answers

Which medication class is most effective for minimizing weight gain or promoting weight loss in T2DM treatment?

<p>SGLT2 inhibitors (D)</p> Signup and view all the answers

What is a limitation of using HbA1c for diagnosing diabetes?

<p>It does not reflect blood glucose levels over the past 2-3 months. (D)</p> Signup and view all the answers

Which SGLT2 inhibitor has the dosing regimen of 5-10 mg daily in the morning?

<p>Dapagliflozin (D)</p> Signup and view all the answers

What is the primary treatment goal for Type 2 Diabetes Mellitus (T2DM) patients according to the American Diabetes Association?

<p>Achieve glycemic control (B)</p> Signup and view all the answers

What diagnostic criterion is essential for Type 2 Diabetes Mellitus (T2DM) diagnosis besides HbA1c?

<p>Fasting plasma glucose test (D)</p> Signup and view all the answers

What is the primary treatment goal for minimizing hypoglycemia and weight gain in Type 2 Diabetes Mellitus (T2DM)?

<p>Decrease FPG levels (D)</p> Signup and view all the answers

Which class of medications for T2DM primarily targets the kidneys to reduce glucose levels in the blood?

<p>Sulfonylureas (A)</p> Signup and view all the answers

What is considered a limitation of using HbA1c for diagnosing Type 2 Diabetes Mellitus (T2DM)?

<p>It can be affected by conditions that shorten red blood cell lifespan (D)</p> Signup and view all the answers

Which criteria are used to diagnose Type 2 Diabetes Mellitus (T2DM) based on random blood glucose levels?

<p>&gt;126 mg/dL with symptoms of hyperglycemia (A)</p> Signup and view all the answers

What fasting plasma glucose (FPG) range indicates a diagnosis of Type 2 Diabetes Mellitus (T2DM)?

<p>&gt;140 mg/dL (A)</p> Signup and view all the answers

How often should testing be performed for patients with normal results to check for prediabetes, according to the guidelines?

<p>Every 3 years (D)</p> Signup and view all the answers

Which class of medications is most effective for minimizing hypoglycemia and weight gain in T2DM treatment?

<p>Sodium glucose cotransporter 2 inhibitors (SGLT2i) (C)</p> Signup and view all the answers

What is the primary treatment goal for T2DM, according to the American Diabetes Association (ADA)?

<p>Achieving an HbA1c level below 7.0% with minimal weight gain (A)</p> Signup and view all the answers

Which of the following SGLT2 inhibitors has the maximum daily dose that depends on GFR?

<p>Canagliflozin (A)</p> Signup and view all the answers

What is the recommended HbA1c level for diagnosing type 2 diabetes mellitus (T2DM)?

<p>6.5% (A)</p> Signup and view all the answers

What are the primary treatment goals for T2DM?

<p>Achieving an HbA1c level below 6.5% with minimal hypoglycemia and weight gain (B)</p> Signup and view all the answers

What is a limitation of using HbA1c for diagnosing diabetes?

<p>HbA1c is not reliable in patients with hemoglobinopathies (B)</p> Signup and view all the answers

What is the primary treatment goal in Type 2 Diabetes Mellitus (T2DM) for minimizing hypoglycemia and weight gain?

<p>Consider GLP1 RA as add-on therapy (C)</p> Signup and view all the answers

Which medication class is most suitable for minimizing weight gain or promoting weight loss in T2DM treatment without established ASCVD, CKD, or HF?

<p>SGLT2 inhibitors (B)</p> Signup and view all the answers

What is a limitation of utilizing HbA1c in the management of T2DM?

<p>Reflects only recent glucose levels (B)</p> Signup and view all the answers

Which of the following is a diagnostic criterion besides HbA1c that is essential for diagnosing T2DM?

<p>Fasting plasma glucose (FPG) levels (D)</p> Signup and view all the answers

For patients with T2DM not at goal, and considering minimizing cost without established ASCVD, CKD, or HF, which medication class should be avoided?

<p>SU (A)</p> Signup and view all the answers

If a patient with T2DM is not at goal and aiming to minimize hypoglycemia without established ASCVD, CKD, or HF, which combination of medications should be considered?

<p>GLP1 RA and DPP4 inhibitor (C)</p> Signup and view all the answers

What is a possible limitation of using HbA1c for diagnosing Type 2 Diabetes Mellitus (T2DM)?

<p>It can be falsely elevated in the presence of chronic kidney disease (C)</p> Signup and view all the answers

To minimize hypoglycemia and weight gain in Type 2 Diabetes Mellitus (T2DM) patients, which class of medications would be beneficial?

<p>GLP-1 receptor agonists (A)</p> Signup and view all the answers

What fasting plasma glucose (FPG) range would indicate a diagnosis of Type 2 Diabetes Mellitus (T2DM)?

<p>&gt;126 mg/dL (A)</p> Signup and view all the answers

Which of the following postprandial oral glucose tolerance test results indicates Type 2 Diabetes Mellitus (T2DM)?

<p>&gt;200 mg/dL (B)</p> Signup and view all the answers

What is the primary treatment goal for Type 2 Diabetes Mellitus (T2DM) patients according to the guidelines?

<p>Achieving optimal blood pressure control (A)</p> Signup and view all the answers

Which of the following is a criterion essential for diagnosing Type 2 Diabetes Mellitus (T2DM) besides HbA1c?

<p>&gt;200 mg/dL random blood glucose with symptoms of hyperglycemia (D)</p> Signup and view all the answers

What is a potential limitation of using HbA1c for diagnosing Type 2 Diabetes Mellitus (T2DM), especially in certain populations?

<p>It may not accurately reflect blood glucose levels in certain racial or ethnic groups (B)</p> Signup and view all the answers

Which class of medications for T2DM primarily targets the kidneys to reduce glucose levels in the blood?

<p>Sodium glucose cotransporter 2 inhibitors (SGLT2i) (D)</p> Signup and view all the answers

Besides HbA1c, what is another essential diagnostic criterion for diagnosing Type 2 Diabetes Mellitus (T2DM)?

<p>Fasting plasma glucose (FPG) (C)</p> Signup and view all the answers

To minimize hypoglycemia and weight gain in Type 2 Diabetes Mellitus (T2DM) patients, which medication class should be considered first?

<p>Glucagon-like peptide 1 receptor agonists (GLP1 RA) (A)</p> Signup and view all the answers

Which criteria are used to diagnose Type 2 Diabetes Mellitus (T2DM) based on random blood glucose levels?

<p>$ ext{Postprandial blood glucose} &gt; 200 ext{ mg/dL}$ (B)</p> Signup and view all the answers

What is a common limitation of using HbA1c for diabetes management that relates to patient variability?

<p>It does not provide real-time measurement of current glucose levels (C)</p> Signup and view all the answers

What is the minimum age recommended for starting testing for diabetes in all patients?

<p>35 years (D)</p> Signup and view all the answers

Which of the following factors is NOT considered in the ADA criteria for testing adults for diabetes?

<p>HDL cholesterol level &gt;250 mg/dL (C)</p> Signup and view all the answers

Besides HbA1c, which test result indicates a diagnosis of prediabetes?

<p>2hr postprandial 75g OGTT: 140-199 mg/dL (B)</p> Signup and view all the answers

What fasting plasma glucose (FPG) level indicates a diagnosis of Type 2 Diabetes Mellitus?

<p>&gt;126 mg/dL (B)</p> Signup and view all the answers

What is a limitation of using HbA1c for diagnosing Type 2 Diabetes Mellitus, especially in certain populations?

<p>It may be affected by certain conditions like anemia. (C)</p> Signup and view all the answers

What is a key consideration for the initiation and maximum dosing of SGLT2 inhibitors in T2DM?

<p>Glomerular filtration rate (GFR) (B)</p> Signup and view all the answers

In T2DM management, which medication class should be avoided in combination with DPP4 inhibitors?

<p>GLP-1 receptor agonists (GLP1 RA) (D)</p> Signup and view all the answers

For T2DM patients aiming to minimize hypoglycemia without established cardiovascular disease, chronic kidney disease, or heart failure, which medication class combination should be considered?

<p>SGLT2 inhibitors or DPP4 inhibitors (B)</p> Signup and view all the answers

Besides HbA1c, what other diagnostic criterion is essential for diagnosing Type 2 Diabetes Mellitus (T2DM)?

<p>Fasting plasma glucose (FPG) levels (A)</p> Signup and view all the answers

What is a common limitation of using HbA1c for diabetes management that relates to certain patient populations?

<p>Interference by certain medications (C)</p> Signup and view all the answers

Which of the following is NOT a primary treatment goal for Type 2 Diabetes Mellitus (T2DM)?

<p>Promoting weight gain (D)</p> Signup and view all the answers

Which medication class has been shown to have cardiovascular benefits in addition to glycemic control for T2DM patients?

<p>Sodium-glucose cotransporter-2 (SGLT2) inhibitors (C)</p> Signup and view all the answers

Which of the following is NOT a limitation of using HbA1c for diagnosing T2DM?

<p>Iron deficiency (C)</p> Signup and view all the answers

Which of the following SGLT2-i has the maximum daily dose that depends on GFR?

<p>Canagliflozin (C)</p> Signup and view all the answers

Which of the following is NOT a diagnostic criterion for T2DM besides HbA1c?

<p>Serum insulin levels (B)</p> Signup and view all the answers

What is the primary treatment goal for Type 2 Diabetes Mellitus (T2DM) according to the American Diabetes Association?

<p>Achieving optimal glycemic control (C)</p> Signup and view all the answers

Which class of medications for T2DM has been shown to have cardiovascular benefits?

<p>SGLT2 inhibitors (D)</p> Signup and view all the answers

Which diagnostic criterion is essential for Type 2 Diabetes Mellitus (T2DM) diagnosis besides HbA1c?

<p>Fasting plasma glucose (FPG) (A)</p> Signup and view all the answers

What is a limitation of using HbA1c for diagnosing Type 2 Diabetes Mellitus (T2DM)?

<p>HbA1c may not accurately reflect glycemic control in certain populations (A)</p> Signup and view all the answers

To minimize hypoglycemia and weight gain in Type 2 Diabetes Mellitus (T2DM) patients, which class of medications would be beneficial?

<p>SGLT2 inhibitors (C)</p> Signup and view all the answers

What is the primary treatment goal in Type 2 Diabetes Mellitus (T2DM) for minimizing hypoglycemia and weight gain?

<p>Minimizing hypoglycemia and weight gain (B)</p> Signup and view all the answers

Which class of medications for T2DM primarily targets the kidneys to reduce glucose levels in the blood?

<p>SGLT2 inhibitors (A)</p> Signup and view all the answers

Which class of medications for T2DM has been shown to have cardiovascular benefits?

<p>SGLT2 inhibitors (B)</p> Signup and view all the answers

Which medication class is most effective for minimizing weight gain or promoting weight loss in T2DM treatment?

<p>GLP-1 agonists (A)</p> Signup and view all the answers

Besides HbA1c, what other diagnostic criterion is essential for diagnosing Type 2 Diabetes Mellitus (T2DM)?

<p>Fasting plasma glucose (FPG) test (B)</p> Signup and view all the answers

What is the typical decrease in A1c when using SGLT2-i as monotherapy?

<p>1.0-1.5% (A)</p> Signup and view all the answers

Which SGLT2 inhibitor has the dosing regimen of 5-10 mg daily in the morning?

<p>Dapagliflozin (D)</p> Signup and view all the answers

For T2DM patients aiming to minimize hypoglycemia without established cardiovascular disease, chronic kidney disease, or heart failure, which medication class combination should be considered?

<p>DPP-4 inhibitors and metformin (C)</p> Signup and view all the answers

Which medication class is most suitable for minimizing weight gain or promoting weight loss in T2DM treatment without established ASCVD, CKD, or HF?

<p>GLP-1 agonists (C)</p> Signup and view all the answers

What is a limitation of using HbA1c for diagnosing Type 2 Diabetes Mellitus (T2DM)?

<p>It is not affected by hemoglobinopathies (A)</p> Signup and view all the answers

Empagliflozin is a medication used for the treatment of type 2 diabetes mellitus.

<p>True (A)</p> Signup and view all the answers

Canagliflozin is a type of GLP-1 receptor agonist for type 2 diabetes treatment.

<p>False (B)</p> Signup and view all the answers

Saxagliptin has been shown to improve cardiovascular outcomes in patients with type 2 diabetes mellitus.

<p>False (B)</p> Signup and view all the answers

Liraglutide has been associated with cardiovascular benefits in patients with type 2 diabetes mellitus.

<p>True (A)</p> Signup and view all the answers

Dapagliflozin is a medication that primarily targets the kidneys to reduce glucose levels in the blood.

<p>True (A)</p> Signup and view all the answers

Semaglutide is a DPP-4 inhibitor used in the management of type 2 diabetes mellitus.

<p>False (B)</p> Signup and view all the answers

SGLT2 inhibitors are commonly associated with weight gain in patients with type 2 diabetes mellitus.

<p>False (B)</p> Signup and view all the answers

Empagliflozin is one of the SGLT2 inhibitors that have shown cardiovascular benefits in type 2 diabetes mellitus.

<p>True (A)</p> Signup and view all the answers

Taking SGLT2 inhibitors may contribute to a reduced risk of cardiovascular events in individuals with type 2 diabetes mellitus.

<p>True (A)</p> Signup and view all the answers

Canagliflozin, as an SGLT2 inhibitor, is ineffective in lowering blood glucose levels in patients with type 2 diabetes mellitus.

<p>False (B)</p> Signup and view all the answers

Sulfonylureas are the most suitable medication class for minimizing weight gain or promoting weight loss in T2DM treatment without established ASCVD, CKD, or HF.

<p>False (B)</p> Signup and view all the answers

One of the diagnostic criteria for T2DM besides HbA1c is fasting plasma glucose (FPG) level.

<p>True (A)</p> Signup and view all the answers

Meglitinides are a medication class primarily targeting the kidneys to reduce glucose levels in the blood for T2DM.

<p>False (B)</p> Signup and view all the answers

A diagnostic criterion essential for T2DM diagnosis besides HbA1c is postprandial oral glucose tolerance test results.

<p>False (B)</p> Signup and view all the answers

Heart failure (HF) is one of the diagnostic criteria for T2DM diagnosis.

<p>False (B)</p> Signup and view all the answers

A1c levels remain constant when using SGLT2 inhibitors as monotherapy for T2DM.

<p>False (B)</p> Signup and view all the answers

Alpha glucosidase inhibitors are effective in lowering blood glucose levels in patients with T2DM.

<p>True (A)</p> Signup and view all the answers

Hemoglobin A1c (HbA1c) is the only diagnostic criterion for T2DM diagnosis.

<p>False (B)</p> Signup and view all the answers

Thiazolidinediones (TZDs) have been shown to have cardiovascular benefits in addition to glycemic control for T2DM patients.

<p>True (A)</p> Signup and view all the answers

Self Monitoring Blood Glucose (SMBG) is one of the primary treatment goals for T2DM.

<p>False (B)</p> Signup and view all the answers

Which class of medications for T2DM primarily targets the kidneys to reduce glucose levels in the blood?

<p>Sodium glucose cotransporter 2 inhibitors (SGLT2i) (D)</p> Signup and view all the answers

What is the primary treatment goal for Type 2 Diabetes Mellitus (T2DM) according to the American Diabetes Association (ADA)?

<p>Reducing cardiovascular risk factors (D)</p> Signup and view all the answers

Which of the following strategies can help minimize hypoglycemia and weight gain in T2DM patients?

<p>Initiating treatment with SGLT2 inhibitors (B)</p> Signup and view all the answers

What is the typical decrease in A1c when using SGLT2-i as monotherapy?

<p>0.5% to 0.7% (D)</p> Signup and view all the answers

Which class of medications for T2DM has been shown to have cardiovascular benefits?

<p>Sodium glucose cotransporter 2 inhibitors (SGLT2i) (C)</p> Signup and view all the answers

Which medication class should be considered first for minimizing cost in T2DM treatment?

<p>Sulfonylureas (SU) (A)</p> Signup and view all the answers

What is the primary treatment goal for minimizing hypoglycemia and weight gain in Type 2 Diabetes Mellitus (T2DM)?

<p>Minimizing hypoglycemia (A)</p> Signup and view all the answers

What is a limitation of utilizing HbA1c in the management of T2DM?

<p>HbA1c does not reflect short-term glucose fluctuations (A)</p> Signup and view all the answers

Which diagnostic criterion is essential for Type 2 Diabetes Mellitus (T2DM) diagnosis besides HbA1c?

<p>Fasting blood glucose (FBG) (A)</p> Signup and view all the answers

What is considered a limitation of using HbA1c for diagnosing Type 2 Diabetes Mellitus (T2DM)?

<p>HbA1c does not reflect short-term glucose fluctuations (B)</p> Signup and view all the answers

Which medication class primarily targets the kidneys to reduce glucose levels in the blood for T2DM patients?

<p>Sodium glucose cotransporter 2 inhibitors (SGLT2i) (C)</p> Signup and view all the answers

Which SGLT2 inhibitor has a dosing regimen of 5-10 mg daily in the morning?

<p>Dapagliflozin (A)</p> Signup and view all the answers

What is the typical decrease in A1c when using SGLT2i as monotherapy?

<p>0.5 - 1.0% (C)</p> Signup and view all the answers

Which of the following SGLT2 inhibitors has a maximum daily dose that depends on GFR?

<p>Canagliflozin (D)</p> Signup and view all the answers

Which class of medications for T2DM has been shown to have cardiovascular benefits?

<p>GLP-1 receptor agonists (C)</p> Signup and view all the answers

What is the primary treatment goal for T2DM patients according to the American Diabetes Association (ADA)?

<p>Minimizing hypoglycemia and weight gain (B)</p> Signup and view all the answers

What is the fasting plasma glucose (FPG) range for diagnosing Type 2 Diabetes Mellitus (T2DM)?

<p>126-140 mg/dL (B)</p> Signup and view all the answers

Which medication class is most effective for minimizing weight gain or promoting weight loss in T2DM treatment?

<p>SGLT2 inhibitors (B)</p> Signup and view all the answers

Which class of medication should be avoided in combination with DPP4i for T2DM treatment?

<p>Sulfonylureas (C)</p> Signup and view all the answers

What is a limitation of utilizing HbA1c in the management of T2DM?

<p>It does not provide information about daily glucose variability (A)</p> Signup and view all the answers

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