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Questions and Answers
Which method is considered the most definitive for diagnosing prostate adenocarcinoma?
Which method is considered the most definitive for diagnosing prostate adenocarcinoma?
What does a Gleason score primarily assess?
What does a Gleason score primarily assess?
Which of the following is NOT classified as a germ cell tumor of the testes?
Which of the following is NOT classified as a germ cell tumor of the testes?
Which histopathological finding is NOT typical for seminoma?
Which histopathological finding is NOT typical for seminoma?
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What is a distinguishing feature of testicular tumors when identified through a physical examination?
What is a distinguishing feature of testicular tumors when identified through a physical examination?
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What is a key gross appearance characteristic of embryonal carcinoma?
What is a key gross appearance characteristic of embryonal carcinoma?
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Which of the following cell types is NOT commonly found in embryonal carcinoma?
Which of the following cell types is NOT commonly found in embryonal carcinoma?
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What is the most common type of cervical carcinoma?
What is the most common type of cervical carcinoma?
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Which of the following is a predisposing factor for cervical carcinoma?
Which of the following is a predisposing factor for cervical carcinoma?
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What is the primary function of hCG in relation to male reproductive system tumors?
What is the primary function of hCG in relation to male reproductive system tumors?
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Which organism is the most common causative agent of vaginitis?
Which organism is the most common causative agent of vaginitis?
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What is a clinical symptom commonly associated with cervical polyps?
What is a clinical symptom commonly associated with cervical polyps?
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Which of the following characteristics describes cervical intraepithelial neoplasia (CIN)?
Which of the following characteristics describes cervical intraepithelial neoplasia (CIN)?
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What is the main cause of benign prostatic hyperplasia (BPH)?
What is the main cause of benign prostatic hyperplasia (BPH)?
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What effect does dihydrotestosterone (DHT) have on glandular and stromal cells of the prostate?
What effect does dihydrotestosterone (DHT) have on glandular and stromal cells of the prostate?
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Which of the following is NOT a storage symptom associated with BPH?
Which of the following is NOT a storage symptom associated with BPH?
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Which drug is commonly used to treat BPH, and what is its mechanism of action?
Which drug is commonly used to treat BPH, and what is its mechanism of action?
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What is a common complication of BPH related to the urinary system?
What is a common complication of BPH related to the urinary system?
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Which microscopic finding is commonly associated with benign prostatic hyperplasia?
Which microscopic finding is commonly associated with benign prostatic hyperplasia?
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In prostate adenocarcinoma, which characteristic is indicative of abnormal gland formation?
In prostate adenocarcinoma, which characteristic is indicative of abnormal gland formation?
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What outcome can prostate adenocarcinoma lead to after metastasis?
What outcome can prostate adenocarcinoma lead to after metastasis?
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What condition is cervical intraepithelial neoplasia associated with?
What condition is cervical intraepithelial neoplasia associated with?
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Which symptom is likely to present at the early stage of cervical intraepithelial neoplasia?
Which symptom is likely to present at the early stage of cervical intraepithelial neoplasia?
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What distinguishes CIN III from CIN I in terms of morphological features?
What distinguishes CIN III from CIN I in terms of morphological features?
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Which symptom is associated with later stages of cervical intraepithelial neoplasia?
Which symptom is associated with later stages of cervical intraepithelial neoplasia?
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What would likely be felt during a bimanual examination in a patient with advanced cervical intraepithelial neoplasia?
What would likely be felt during a bimanual examination in a patient with advanced cervical intraepithelial neoplasia?
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What happens to cell maturation and differentiation in CIN III?
What happens to cell maturation and differentiation in CIN III?
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Which symptom is a result of obstructive uropathy due to metastasis in advanced cervical intraepithelial neoplasia?
Which symptom is a result of obstructive uropathy due to metastasis in advanced cervical intraepithelial neoplasia?
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What describes the cellular composition of carcinoma in situ found in CIN III?
What describes the cellular composition of carcinoma in situ found in CIN III?
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What is a common clinical feature of invasive ductal carcinoma regarding the nipple?
What is a common clinical feature of invasive ductal carcinoma regarding the nipple?
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Which of the following tumour markers is NOT typically used in the assessment of breast cancer?
Which of the following tumour markers is NOT typically used in the assessment of breast cancer?
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What is a characteristic histopathological finding of ductal carcinoma in situ?
What is a characteristic histopathological finding of ductal carcinoma in situ?
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Which diagnostic method is least invasive when diagnosing breast cancer?
Which diagnostic method is least invasive when diagnosing breast cancer?
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What does TNM staging primarily assess in breast tumors?
What does TNM staging primarily assess in breast tumors?
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What type of tumour is entirely composed of cytotrophoblast or syncytiotrophoblast?
What type of tumour is entirely composed of cytotrophoblast or syncytiotrophoblast?
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Which of the following is NOT a clinical feature of a patient with gestational choriocarcinoma?
Which of the following is NOT a clinical feature of a patient with gestational choriocarcinoma?
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What is one of the risk factors for polycystic ovarian disease?
What is one of the risk factors for polycystic ovarian disease?
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What is the primary symptom associated with ovarian tumours?
What is the primary symptom associated with ovarian tumours?
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Which class of ovarian tumours includes the dysgerminoma?
Which class of ovarian tumours includes the dysgerminoma?
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Which of the following is a risk factor for developing ovarian tumours?
Which of the following is a risk factor for developing ovarian tumours?
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What type of ovarian tumour is associated with the presence of Krukenberg tumour?
What type of ovarian tumour is associated with the presence of Krukenberg tumour?
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Which type of cyst is correctly matched with its description?
Which type of cyst is correctly matched with its description?
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Study Notes
Benign and Malignant Diseases of the Male Reproductive System
- Benign Prostatic Hyperplasia (BPH) primarily affects men aged 60 and above
- Hormonal imbalance, specifically an increase in the estrogen-to-testosterone ratio, contributes to the development of BPH
- As testosterone converts to dihydrotestosterone (DHT) by 5α-reductase, this increase in DHT stimulates the proliferation of glandular and stromal cells in the prostate, leading to median lobe enlargement
- The enlarged median lobe compresses the urethra, causing bladder outlet obstruction
- Symptoms often include nocturia, urinary retention, dribbling, and urgency
- Finasteride is a common treatment for BPH, inhibiting the conversion of testosterone to DHT
- Patients may experience voiding symptoms (hesitancy, dribbling, retention) and storage symptoms (urgency, nocturia, frequency)
- Common complications of BPH include urethral obstruction and bladder atony
Prostate Adenocarcinoma
- Prostate adenocarcinoma originates from the glandular epithelium
- It disrupts the prostate architecture through abnormal gland formation within existing glands
- Manifestations often include large nuclei, prominent nucleoli, and loss of basal cells
- Potential metastasis leads to bone involvement, resulting in osteoblast or osteoclast activity
- Diagnosis methods such as digital rectal examination, transrectal ultrasound, prostate-specific antigen (PSA) tests, and MRI are employed
Testicular Tumors
- Testicular tumors encompass germ cell and non-germ cell types
- Germ cell tumors include seminoma, spermatocytic carcinoma, choriocarcinoma, and embryonal carcinoma
- Non-germ cell tumors include Leydig cell and Sertoli cell tumors
- Seminoma tumors do not secrete any tumor markers, and treatment is typically possible even in malignant cases
Diseases of Vulva, Vagina, and Cervix
- Vulvar intraepithelial neoplasia (VIN) is a neoplasm of the vulva
- This disease, potentially caused by human papillomavirus (HPV) types 6 and 11, can manifest as anogenital warts
- This isn't typically considered malignant, but early detection is necessary
- Vaginitis is often caused by Gardnerella vaginalis
Diseases of the Uterus
- Leiomyoma, or uterine fibroids, are benign tumors arising from the smooth muscle layer of the myometrium
- Risk factors may include genetics, oral contraceptives, and estrogen
- Symptoms may be asymptomatic, or include menorrhagia, metrorrhagia, or possibly both
Endometriosis
- Endometriosis is characterized by the presence of ectopic endometrial tissue outside the uterine cavity
- Potential causes include implantation theory, coelomic metaplasia theory, and chemical substance induction
- Common symptoms include period pain (dysmenorrhea), painful intercourse (dyspareunia), excessive menstrual bleeding (menorrhagia), and chronic pelvic pain
Gestational Trophoblastic Disease (GTD)
- GTD comprises conditions with abnormal trophoblastic tissue development
- Two main types are hydatidiform mole and choriocarcinoma.
- Hydatiform mole exhibits grape-like, fluid-filled villi
- Possible complications include choriocarcinoma
Diseases of the Fallopian Tubes and Ovaries
- Ovarian cysts, including luteal, corpus luteum, follicular, and polycystic, are potential conditions
- Risk factors of polycystic ovarian disease include obesity, hirsutism, anovulation, and oligomenorrhea
Diseases of the Breast
- Fibrocystic disease of the breast is a benign condition characterized by the formation of lumps, nipple discharge, calcification, apocrine metaplasia, and fibrosis
- Ductal carcinoma in situ involves malignant cells within the ducts of the breast but does not penetrate the basement membrane; invasive ductal carcinoma involves malignant cells that breach the basement membrane. Malignant breast diseases can metastasize, leading to more serious health concerns.
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Description
Test your knowledge on benign and malignant diseases of the male reproductive system, including conditions like Benign Prostatic Hyperplasia (BPH) and prostate adenocarcinoma. Understand the causes, symptoms, and treatments involved to improve patient outcomes in men's health.