Male Reproductive Health Quiz
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Questions and Answers

Which method is considered the most definitive for diagnosing prostate adenocarcinoma?

  • Biopsy (correct)
  • Transrectal ultrasound
  • Prostate specific antigen
  • Digital rectal examination
  • What does a Gleason score primarily assess?

  • Patient's age
  • Presence of metastasis
  • Size of the prostate
  • Aggressiveness of cancerous cells (correct)
  • Which of the following is NOT classified as a germ cell tumor of the testes?

  • Yolk sac tumor
  • Seminoma
  • Sertoli cell tumor (correct)
  • Choriocarcinoma
  • Which histopathological finding is NOT typical for seminoma?

    <p>Evidence of hemorrhage</p> Signup and view all the answers

    What is a distinguishing feature of testicular tumors when identified through a physical examination?

    <p>Palpable masses</p> Signup and view all the answers

    What is a key gross appearance characteristic of embryonal carcinoma?

    <p>Gray-white in color</p> Signup and view all the answers

    Which of the following cell types is NOT commonly found in embryonal carcinoma?

    <p>Squamous cells</p> Signup and view all the answers

    What is the most common type of cervical carcinoma?

    <p>Squamous cell carcinoma</p> Signup and view all the answers

    Which of the following is a predisposing factor for cervical carcinoma?

    <p>Chlamydia infection</p> Signup and view all the answers

    What is the primary function of hCG in relation to male reproductive system tumors?

    <p>To detect choriocarcinoma</p> Signup and view all the answers

    Which organism is the most common causative agent of vaginitis?

    <p>Gardnerella vaginalis</p> Signup and view all the answers

    What is a clinical symptom commonly associated with cervical polyps?

    <p>Vaginal bleeding between menses</p> Signup and view all the answers

    Which of the following characteristics describes cervical intraepithelial neoplasia (CIN)?

    <p>It is a premalignant condition</p> Signup and view all the answers

    What is the main cause of benign prostatic hyperplasia (BPH)?

    <p>Hormonal imbalance with decreased testosterone</p> Signup and view all the answers

    What effect does dihydrotestosterone (DHT) have on glandular and stromal cells of the prostate?

    <p>Stimulates proliferation of cells</p> Signup and view all the answers

    Which of the following is NOT a storage symptom associated with BPH?

    <p>Hesitancy</p> Signup and view all the answers

    Which drug is commonly used to treat BPH, and what is its mechanism of action?

    <p>Finasteride; it inhibits 5a-reductase</p> Signup and view all the answers

    What is a common complication of BPH related to the urinary system?

    <p>Hydronephrosis</p> Signup and view all the answers

    Which microscopic finding is commonly associated with benign prostatic hyperplasia?

    <p>Nodules of glands</p> Signup and view all the answers

    In prostate adenocarcinoma, which characteristic is indicative of abnormal gland formation?

    <p>Loss of basal cells</p> Signup and view all the answers

    What outcome can prostate adenocarcinoma lead to after metastasis?

    <p>Formation of osteoblasts or osteoclasts</p> Signup and view all the answers

    What condition is cervical intraepithelial neoplasia associated with?

    <p>HPV infection, specifically types 16 or 18</p> Signup and view all the answers

    Which symptom is likely to present at the early stage of cervical intraepithelial neoplasia?

    <p>Bleeding between menses</p> Signup and view all the answers

    What distinguishes CIN III from CIN I in terms of morphological features?

    <p>Severe dysplasia affecting all layers of the epithelium</p> Signup and view all the answers

    Which symptom is associated with later stages of cervical intraepithelial neoplasia?

    <p>Back pain</p> Signup and view all the answers

    What would likely be felt during a bimanual examination in a patient with advanced cervical intraepithelial neoplasia?

    <p>An enlarged cervix encircled by a tumor</p> Signup and view all the answers

    What happens to cell maturation and differentiation in CIN III?

    <p>Cells show no maturation or differentiation</p> Signup and view all the answers

    Which symptom is a result of obstructive uropathy due to metastasis in advanced cervical intraepithelial neoplasia?

    <p>Difficulty urinating</p> Signup and view all the answers

    What describes the cellular composition of carcinoma in situ found in CIN III?

    <p>Presence of various types of cells with severe dysplasia</p> Signup and view all the answers

    What is a common clinical feature of invasive ductal carcinoma regarding the nipple?

    <p>Retracted nipple</p> Signup and view all the answers

    Which of the following tumour markers is NOT typically used in the assessment of breast cancer?

    <p>CA-125</p> Signup and view all the answers

    What is a characteristic histopathological finding of ductal carcinoma in situ?

    <p>Malignant cells proliferating without breaching the basal membrane</p> Signup and view all the answers

    Which diagnostic method is least invasive when diagnosing breast cancer?

    <p>Mammography</p> Signup and view all the answers

    What does TNM staging primarily assess in breast tumors?

    <p>Size and spread of the tumor</p> Signup and view all the answers

    What type of tumour is entirely composed of cytotrophoblast or syncytiotrophoblast?

    <p>Gestational choriocarcinoma</p> Signup and view all the answers

    Which of the following is NOT a clinical feature of a patient with gestational choriocarcinoma?

    <p>Ovarian cyst</p> Signup and view all the answers

    What is one of the risk factors for polycystic ovarian disease?

    <p>Hirsutism</p> Signup and view all the answers

    What is the primary symptom associated with ovarian tumours?

    <p>Weight loss</p> Signup and view all the answers

    Which class of ovarian tumours includes the dysgerminoma?

    <p>Germ cell tumours</p> Signup and view all the answers

    Which of the following is a risk factor for developing ovarian tumours?

    <p>Aging</p> Signup and view all the answers

    What type of ovarian tumour is associated with the presence of Krukenberg tumour?

    <p>Cancerous cells that metastasize to ovaries</p> Signup and view all the answers

    Which type of cyst is correctly matched with its description?

    <p>Polycystic ovarian cyst - occurs in conjunction with PCOS</p> Signup and view all the answers

    Study Notes

    Benign and Malignant Diseases of the Male Reproductive System

    • Benign Prostatic Hyperplasia (BPH) primarily affects men aged 60 and above
    • Hormonal imbalance, specifically an increase in the estrogen-to-testosterone ratio, contributes to the development of BPH
    • As testosterone converts to dihydrotestosterone (DHT) by 5α-reductase, this increase in DHT stimulates the proliferation of glandular and stromal cells in the prostate, leading to median lobe enlargement
    • The enlarged median lobe compresses the urethra, causing bladder outlet obstruction
    • Symptoms often include nocturia, urinary retention, dribbling, and urgency
    • Finasteride is a common treatment for BPH, inhibiting the conversion of testosterone to DHT
    • Patients may experience voiding symptoms (hesitancy, dribbling, retention) and storage symptoms (urgency, nocturia, frequency)
    • Common complications of BPH include urethral obstruction and bladder atony

    Prostate Adenocarcinoma

    • Prostate adenocarcinoma originates from the glandular epithelium
    • It disrupts the prostate architecture through abnormal gland formation within existing glands
    • Manifestations often include large nuclei, prominent nucleoli, and loss of basal cells
    • Potential metastasis leads to bone involvement, resulting in osteoblast or osteoclast activity
    • Diagnosis methods such as digital rectal examination, transrectal ultrasound, prostate-specific antigen (PSA) tests, and MRI are employed

    Testicular Tumors

    • Testicular tumors encompass germ cell and non-germ cell types
    • Germ cell tumors include seminoma, spermatocytic carcinoma, choriocarcinoma, and embryonal carcinoma
    • Non-germ cell tumors include Leydig cell and Sertoli cell tumors
    • Seminoma tumors do not secrete any tumor markers, and treatment is typically possible even in malignant cases

    Diseases of Vulva, Vagina, and Cervix

    • Vulvar intraepithelial neoplasia (VIN) is a neoplasm of the vulva
    • This disease, potentially caused by human papillomavirus (HPV) types 6 and 11, can manifest as anogenital warts
    • This isn't typically considered malignant, but early detection is necessary
    • Vaginitis is often caused by Gardnerella vaginalis

    Diseases of the Uterus

    • Leiomyoma, or uterine fibroids, are benign tumors arising from the smooth muscle layer of the myometrium
    • Risk factors may include genetics, oral contraceptives, and estrogen
    • Symptoms may be asymptomatic, or include menorrhagia, metrorrhagia, or possibly both

    Endometriosis

    • Endometriosis is characterized by the presence of ectopic endometrial tissue outside the uterine cavity
    • Potential causes include implantation theory, coelomic metaplasia theory, and chemical substance induction
    • Common symptoms include period pain (dysmenorrhea), painful intercourse (dyspareunia), excessive menstrual bleeding (menorrhagia), and chronic pelvic pain

    Gestational Trophoblastic Disease (GTD)

    • GTD comprises conditions with abnormal trophoblastic tissue development
    • Two main types are hydatidiform mole and choriocarcinoma.
    • Hydatiform mole exhibits grape-like, fluid-filled villi
    • Possible complications include choriocarcinoma

    Diseases of the Fallopian Tubes and Ovaries

    • Ovarian cysts, including luteal, corpus luteum, follicular, and polycystic, are potential conditions
    • Risk factors of polycystic ovarian disease include obesity, hirsutism, anovulation, and oligomenorrhea

    Diseases of the Breast

    • Fibrocystic disease of the breast is a benign condition characterized by the formation of lumps, nipple discharge, calcification, apocrine metaplasia, and fibrosis
    • Ductal carcinoma in situ involves malignant cells within the ducts of the breast but does not penetrate the basement membrane; invasive ductal carcinoma involves malignant cells that breach the basement membrane. Malignant breast diseases can metastasize, leading to more serious health concerns.

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    Description

    Test your knowledge on benign and malignant diseases of the male reproductive system, including conditions like Benign Prostatic Hyperplasia (BPH) and prostate adenocarcinoma. Understand the causes, symptoms, and treatments involved to improve patient outcomes in men's health.

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