Male Genitourinary System Diseases
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Questions and Answers

What is the condition known as where the urethral opening is located along the ventral aspect of the penis?

  • Hypospadias (correct)
  • Paraphimosis
  • Epispadias
  • Phimosis

Which type of penile neoplasm is most commonly reported?

  • Melanoma
  • Basal cell carcinoma
  • Squamous cell carcinoma (correct)
  • Rhabdomyosarcoma

What percentage of all cancers in males in the U.S. do penile neoplasms account for?

  • 2.5%
  • 0.1%
  • 1.0%
  • 0.4% (correct)

What is a potential consequence of a constricted urethral opening due to hypospadias?

<p>Increased urinary tract infections (D)</p> Signup and view all the answers

Which of the following is a less common condition compared to hypospadias, characterized by an opening along the dorsal aspect of the penis?

<p>Epispadias (D)</p> Signup and view all the answers

What is the primary histologic feature of non-seminomatous tumors?

<p>They often present as a mixture of multiple cell types (B)</p> Signup and view all the answers

Which of the following statements is true regarding the prognosis of testicular tumors?

<p>Early-stage seminomas have a high cure rate (B)</p> Signup and view all the answers

What type of tumor markers are associated with non-seminomatous tumors?

<p>Alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG) (C)</p> Signup and view all the answers

Which of the following describes a significant risk factor for developing non-seminomatous tumors?

<p>Presence of cryptorchidism (D)</p> Signup and view all the answers

Which statement about the treatment of seminomas is accurate?

<p>They are sensitive to both chemotherapy and radiation (B)</p> Signup and view all the answers

What clinical feature is often linked to the presence of non-seminomatous tumors?

<p>Even small tumors can present with extensive metastases (D)</p> Signup and view all the answers

Which type of testicular tumor is known to have the lowest cure rate?

<p>Choriocarcinoma (C)</p> Signup and view all the answers

In adults, which cell type is predominantly responsible for non-seminomatous tumors?

<p>Germ cells (C)</p> Signup and view all the answers

What condition is commonly associated with uncircumcised men over age 40?

<p>HPV Type 16/18 Infection (D)</p> Signup and view all the answers

What stage is classified as Bowen disease?

<p>Ca in-situ (D)</p> Signup and view all the answers

Which factor increases the risk of testicular cancer according to the content?

<p>Undescended Testis (A)</p> Signup and view all the answers

What is the most common complication of mumps in adults?

<p>Orchitis (C)</p> Signup and view all the answers

What is a key indicator of squamous cell carcinoma on the penis?

<p>Crusted plaque (A)</p> Signup and view all the answers

Which type of testicular neoplasm has a peak incidence in males aged 15-34?

<p>Germ Cell Tumors (A)</p> Signup and view all the answers

What complication does torsion of the spermatic cord lead to?

<p>Venous expansion (C)</p> Signup and view all the answers

What percentage of uncircumcised men might develop squamous cell carcinoma?

<p>Rare (D)</p> Signup and view all the answers

What symptom is more common in epididymitis compared to orchitis?

<p>Tenderness and swelling (A)</p> Signup and view all the answers

What is a potential outcome of untreated torsion of the spermatic cord?

<p>Testicular infarction (B)</p> Signup and view all the answers

Flashcards

Penile Hypospadias

A congenital abnormality where the opening of the urethra is along the ventral (underside) of the penis.

Penile Epispadias

A less common congenital abnormality where the urethra opens along the dorsal (upper) side of the penis.

Penile Squamous Cell Carcinoma

The most common type of cancer found on the penis.

Urethral Malformations

Problems with the urethral opening, location, or structure, often leading to urinary tract infections or obstructions.

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Genitourinary System

The organs that comprise the excretory and reproductive systems in males.

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Penile Neoplasms

Rare cancers of the penis, most often squamous cell carcinoma.

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Squamous Cell Carcinoma

A type of cancer that starts in the flat cells of the skin or lining of internal organs.

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Cryptorchidism

Failure of one or both testicles to descend into the scrotum during fetal development.

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Testicular cancer

Cancer of the testicles, often occurring between ages 15 and 34.

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Epididymitis

Inflammation of the epididymis, a tube that sits atop the testicle.

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Orchitis

Inflammation of the testes.

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Testicular torsion

Twisting of the spermatic cord, causing a sudden onset of testicular pain.

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Germ Cell Tumors

Common type of testicular cancer, divided into seminomas and non-seminomas.

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HPV 16/18 infection

Human Papillomavirus types 16 and 18 that can be associated with precancerous lesions on the penis.

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Epithelial Dysplasia

Abnormal growth of cells lining the skin in the penis causing a premalignant lesion.

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Non-seminomatous Tumors

A heterogeneous group of testicular germ cell tumors, that account for most painless testicular enlargements and often spread early.

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Seminoma

A type of testicular germ cell tumor arising from the seminiferous tubules, tends to be indolent (slow-growing), and is often confined to the testis initially.

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Undescended Testis

A risk factor for non-seminomatous tumors, increasing the risk 3-5 times.

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Tumor Markers AFP and HCG

Proteins that can be elevated in blood samples, used to monitor non-seminomatous tumors or to assess the malignancy involved.

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Embryonal Carcinoma

A type of non-seminomatous germ cell tumor that tends to spread early, via lymphatics and blood vessels.

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Prognosis of Germ Cell Tumors

High cure rate, especially for early-stage seminomas (95%). Non-seminomatous tumors are often curable with chemo (90%).

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Hutchinson's Triad

A rare but severe triad of symptoms (notched incisors, interstitial keratitis, and Hutchinson’s teeth), potentially associated with a rare form of germ cell tumor such as a choriocarcinoma.

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Study Notes

Male Genitourinary System Diseases

  • Overview: Includes congenital/neoplastic conditions of the penis, disorders of the testis, prostate, urinary bladder neoplasms, and sexually transmitted diseases.
  • Penile Lesions:
    • Malformations: Hypospadias (urethral opening on ventral side), Epispadias (urethral opening on dorsal side). Can cause urinary tract infections and urinary incontinence.
    • Penile Neoplasms: Squamous cell carcinoma is common, often found in uncircumcised men over 40. Associated with HPV infection and precancerous lesions.
  • Scrotum, Testis, and Epididymis:
    • Scrotum: Inflammatory processes (infections, dermatoses), rare neoplasms (often squamous cell carcinomas); Associated with occupational factors in some cases.
    • Disorders of the Testes: Cryptorchidism (undescended testis), which increases risk for testicular cancer. Vascular disturbances include torsion.
    • Testicular Neoplasms: Germ cell tumors (most common), non-seminomatous and seminomas. Increased risk in cryptorchid patients.
  • Prostate Disorders:
    • Inflammatory lesions (prostatitis): Often related to UTI (often E. coli) or chronic pelvic pain.
    • Nodular Hyperplasia (BPH): Common condition affecting older men, related to hormonal stimulation, where enlarged prostate compresses the urethra leading to urinary obstruction.
    • Carcinoma: Adenocarcinoma, is the most common prostate cancer in men over 50. Can metastasize to lymph nodes and bone. Screening often involves digital rectal examination and PSA (prostate-specific antigen) testing. Elevated PSA can indicate problems but doesn't guarantee cancer in all cases. Treatment varies, often including surgery, radiation therapy, and hormonal therapies based on the stage of disease.

Disorders of the Urinary Bladder

  • Bladder Cancer: Predominantly urothelial carcinoma, occurring frequently in men aged 50 to 80. Characterized by painless hematuria (blood in urine), related risk factors include smoking, prior chronic bladder infections, and exposure to carcinogens. Diagnosis often includes imaging and cystoscopy.
  • Urothelial Carcinoma: Treatment options include transurethral resection, immunotherapy, and radical cystectomy. Treatment and prognosis depend heavily on the stage and grade of the tumor.

Sexually Transmitted Infections

  • Syphilis: Caused by Treponema pallidum, transmitted via direct contact with cutaneous or mucosal lesions. Three stages (primary, secondary, tertiary) with distinct symptoms. Can lead to serious complications if left untreated. Congenital syphilis can result from transmission during pregnancy, causing various defects in newborns.

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Related Documents

Genitourinary Disease PDF

Description

Explore the various diseases affecting the male genitourinary system, from congenital conditions to neoplasms. This quiz covers penile lesions, disorders of the testis, and urinary bladder neoplasms, along with their implications and management. Test your knowledge on these critical health topics!

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