Male Genital Disorders

Hypospadias

• Opening of the urethra on the inferior surface of the penis
• Caused by failure of the urethral folds to close

Epispadias

• Opening of the urethra on the superior surface of the penis
• Due to abnormal positioning of the genital tubercle
• Associated with bladder exstrophy

Condyloma Acuminatum

• Benign warty growth on genital skin
• Caused by HPV type 6 or 11
• Characterized by koilocytic change (Figure 14.1)

Lymphogranuloma Venereum

• Necrotizing granulomatous inflammation of the inguinal lymphatics and lymph nodes
• Sexually transmitted infection caused by Chlamydia trachomatis (serotypes L1-L3)
• Can lead to fibrosis and perianal involvement, potentially causing rectal stricture

Squamous Cell Carcinoma

• Malignant proliferation of squamous cells of the penile skin
• Risk factors:
  • High-risk HPV (in two-thirds of cases)
  • Lack of circumcision (foreskin acts as a nidus for inflammation and irritation if not properly maintained)
• Precursor in situ lesions:
  • Bowen disease (in situ carcinoma of the penile shaft or scrotum that presents as leukoplakia)
  • Erythroplasia of Queyrat (in situ carcinoma on the glans that presents as erythroplakia)
  • Bowenoid papulosis (in situ carcinoma that presents as multiple reddish papules, more common in younger patients, and does not progress to invasive carcinoma)

This quiz covers various male genital disorders, including hypospadias, epispadias, and squamous cell carcinoma. It discusses their causes, characteristics, and associated complications. Test your knowledge on these important medical conditions.