Questions and Answers
What is the primary treatment for P. Vivax infection?
Which of the following is not included in Artemisinin-based combination therapy (ACT)?
During which trimester of pregnancy is Quinine salt recommended for treating P. Falciparum?
In which scenario is Primaquine contraindicated?
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What dosage of Artesunate is prescribed for treatment?
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Study Notes
Treatment Overview
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P. vivax: First-line treatment consists of Chloroquine combined with Primaquine.
- Chloroquine: Administer 25 mg/kg over three days.
- Primaquine: Dosage 0.25 mg/kg for 14 days, with alternative dosing options (DI: 10 mg/kg, Da: 10 mg/kg, D3: 5 mg/kg).
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P. falciparum: Treated with Artemisinin-based Combination Therapy (ACT), as Chloroquine is ineffective.
- Two types of ACT: ACT-SP and ACT-AL.
ACT Components
- A - Artemether: A key component of ACT.
- L - Lumefantrine: Another essential component in ACT.
- S - Sulphadoxine: Part of the ACT regimen.
- P - Pyromethamine: Included in combination therapies for P. falciparum.
Drug Dosages
- Artesunate: Administer 4 mg/kg for three consecutive days.
- Primaquine: Administer 0.75 mg/kg on Day of Assessment (Da).
Regional Treatment Guidelines
- Outside the North-East: Treat with ACT-SP for three days, combined with Primaquine on Da.
- North-Eastern States: Use ACT-AL for three days, also with Primaquine on Da.
Treatment Regimen Highlights
- Initial Day (DI): Administer A, S, P on the first day; follow with Artesunate on Days 2 and 3, and Primaquine on Da.
P. falciparum and Pregnancy
- First Trimester: Treat with Quinine salt.
- Second and Third Trimester: Administer area-specific ACT to ensure safety and effectiveness.
Contraindications for Primaquine
- Pregnancy: Use is not safe.
- Infants: Contraindicated for young children.
- G-6 PD deficiency: Cannot be used in patients with this condition.
Mixed Infections Treatment
- For co-infection of P. falciparum and P. vivax: Administer area-specific ACT for three days alongside Primaquine for 14 days.
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Description
This quiz covers the treatment options for malaria, focusing on P. Vivax and P. Falciparum. Learn about the recommended drugs, dosages, and the details of Artemisinin-based Combination Therapy (ACT). Test your knowledge on effective malaria management.
