Malaria: Plasmodium and Transmission

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20 Questions

Which of the following is the primary host and transmission vector for malaria?

Female mosquitoes

Which type of Plasmodium causes malaria?

Sporozoa

What is the mechanism of action of Proguanil as an antimalarial drug?

Acts as a folate antagonist

Which combination is contraindicated in individuals with a history of epilepsy, psychiatric disorders, or severe hepatic impairment for malaria treatment?

Atovaquone + Proguanil

What is the chemical class of Lumefantrine as an antimalarial drug?

Aryl amino alcohol

Which antimalarial drug mechanism is to block Ca+2-dependent ATPase channels on infected cell membranes?

Artemether

What type of activity does Quinine exhibit in the treatment of malaria?

Blood schizonticidal

What should pregnant individuals do when taking Atovaquone for malaria treatment?

Avoid taking it

Why is Primaquine not recommended as a prophylactic regimen in individuals with renal impairment?

It requires dosage adjustment

How do individuals minimize mosquito biting to prevent malaria transmission?

Apply DEET mosquito repellent

Which drug is the most effective in preventing transmission of malaria?

Proguanil

Which drug is contraindicated in patients with a history of severe hepatic impairment?

Artemether + mefloquine

Which drug is most effective against the invasive trophozoites in amoebic dysentery?

Metronidazole

Which drug is ineffective against cestodes and trematodes (flatworms)?

Pyrantel embonate

Which drug is not effective against blood schizonts in malaria?

Primaquine

Which drug is a potent cholinesterase inhibitor used for headlice treatment?

Malathion

Which drug damages the amoebic DNA and leads to parasitic apoptosis?

Metronidazole

Which drug prevents the polymerization of parasitic β-tubulin and inhibits microtubule-dependent pathways?

Praziquantel

Which drug is a GABA agonist that causes reversible inhibition of neuromuscular transmission in parasites?

Piperazine

Which drug is a potent broad-spectrum anthelminitic that damages the worm in the intestinal site?

Praziquantel

Learn about the primary host and transmission vector of malaria, caused by the parasitic sporozoa Plasmodium. Explore the four types of Plasmodium parasites and their characteristics, as well as how these unicellular eukaryotic organisms evade host antibodies and manipulate the immune system. Dive into antimalarial treatments such as Proguanil, Doxycycline, Mefloquine, and Atova...

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