Malaria: Plasmodium and Transmission
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Questions and Answers

Which of the following is the primary host and transmission vector for malaria?

  • Ticks
  • Female mosquitoes (correct)
  • Fleas
  • Male mosquitoes
  • Which type of Plasmodium causes malaria?

  • Amoebas
  • Sporozoa (correct)
  • Ciliates
  • Flagellates
  • What is the mechanism of action of Proguanil as an antimalarial drug?

  • Blocks protein synthesis
  • Inhibits haem polymerase
  • Targets mitochondria
  • Acts as a folate antagonist (correct)
  • Which combination is contraindicated in individuals with a history of epilepsy, psychiatric disorders, or severe hepatic impairment for malaria treatment?

    <p>Atovaquone + Proguanil</p> Signup and view all the answers

    What is the chemical class of Lumefantrine as an antimalarial drug?

    <p>Aryl amino alcohol</p> Signup and view all the answers

    Which antimalarial drug mechanism is to block Ca+2-dependent ATPase channels on infected cell membranes?

    <p>Artemether</p> Signup and view all the answers

    What type of activity does Quinine exhibit in the treatment of malaria?

    <p>Blood schizonticidal</p> Signup and view all the answers

    What should pregnant individuals do when taking Atovaquone for malaria treatment?

    <p>Avoid taking it</p> Signup and view all the answers

    Why is Primaquine not recommended as a prophylactic regimen in individuals with renal impairment?

    <p>It requires dosage adjustment</p> Signup and view all the answers

    How do individuals minimize mosquito biting to prevent malaria transmission?

    <p>Apply DEET mosquito repellent</p> Signup and view all the answers

    Which drug is the most effective in preventing transmission of malaria?

    <p>Proguanil</p> Signup and view all the answers

    Which drug is contraindicated in patients with a history of severe hepatic impairment?

    <p>Artemether + mefloquine</p> Signup and view all the answers

    Which drug is most effective against the invasive trophozoites in amoebic dysentery?

    <p>Metronidazole</p> Signup and view all the answers

    Which drug is ineffective against cestodes and trematodes (flatworms)?

    <p>Pyrantel embonate</p> Signup and view all the answers

    Which drug is not effective against blood schizonts in malaria?

    <p>Primaquine</p> Signup and view all the answers

    Which drug is a potent cholinesterase inhibitor used for headlice treatment?

    <p>Malathion</p> Signup and view all the answers

    Which drug damages the amoebic DNA and leads to parasitic apoptosis?

    <p>Metronidazole</p> Signup and view all the answers

    Which drug prevents the polymerization of parasitic β-tubulin and inhibits microtubule-dependent pathways?

    <p>Praziquantel</p> Signup and view all the answers

    Which drug is a GABA agonist that causes reversible inhibition of neuromuscular transmission in parasites?

    <p>Piperazine</p> Signup and view all the answers

    Which drug is a potent broad-spectrum anthelminitic that damages the worm in the intestinal site?

    <p>Praziquantel</p> Signup and view all the answers

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