Malaria: Plasmodium and Transmission
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Questions and Answers

Which of the following is the primary host and transmission vector for malaria?

  • Ticks
  • Female mosquitoes (correct)
  • Fleas
  • Male mosquitoes

Which type of Plasmodium causes malaria?

  • Amoebas
  • Sporozoa (correct)
  • Ciliates
  • Flagellates

What is the mechanism of action of Proguanil as an antimalarial drug?

  • Blocks protein synthesis
  • Inhibits haem polymerase
  • Targets mitochondria
  • Acts as a folate antagonist (correct)

Which combination is contraindicated in individuals with a history of epilepsy, psychiatric disorders, or severe hepatic impairment for malaria treatment?

<p>Atovaquone + Proguanil (B)</p> Signup and view all the answers

What is the chemical class of Lumefantrine as an antimalarial drug?

<p>Aryl amino alcohol (C)</p> Signup and view all the answers

Which antimalarial drug mechanism is to block Ca+2-dependent ATPase channels on infected cell membranes?

<p>Artemether (C)</p> Signup and view all the answers

What type of activity does Quinine exhibit in the treatment of malaria?

<p>Blood schizonticidal (D)</p> Signup and view all the answers

What should pregnant individuals do when taking Atovaquone for malaria treatment?

<p>Avoid taking it (C)</p> Signup and view all the answers

Why is Primaquine not recommended as a prophylactic regimen in individuals with renal impairment?

<p>It requires dosage adjustment (D)</p> Signup and view all the answers

How do individuals minimize mosquito biting to prevent malaria transmission?

<p>Apply DEET mosquito repellent (D)</p> Signup and view all the answers

Which drug is the most effective in preventing transmission of malaria?

<p>Proguanil (B)</p> Signup and view all the answers

Which drug is contraindicated in patients with a history of severe hepatic impairment?

<p>Artemether + mefloquine (C)</p> Signup and view all the answers

Which drug is most effective against the invasive trophozoites in amoebic dysentery?

<p>Metronidazole (B)</p> Signup and view all the answers

Which drug is ineffective against cestodes and trematodes (flatworms)?

<p>Pyrantel embonate (B)</p> Signup and view all the answers

Which drug is not effective against blood schizonts in malaria?

<p>Primaquine (C)</p> Signup and view all the answers

Which drug is a potent cholinesterase inhibitor used for headlice treatment?

<p>Malathion (C)</p> Signup and view all the answers

Which drug damages the amoebic DNA and leads to parasitic apoptosis?

<p>Metronidazole (A)</p> Signup and view all the answers

Which drug prevents the polymerization of parasitic β-tubulin and inhibits microtubule-dependent pathways?

<p>Praziquantel (B)</p> Signup and view all the answers

Which drug is a GABA agonist that causes reversible inhibition of neuromuscular transmission in parasites?

<p>Piperazine (D)</p> Signup and view all the answers

Which drug is a potent broad-spectrum anthelminitic that damages the worm in the intestinal site?

<p>Praziquantel (A)</p> Signup and view all the answers

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