Podcast
Questions and Answers
Which factor is the predominant factor in protein stability?
Which factor is the predominant factor in protein stability?
- Disulfide bond
- Hydrophobic effect (correct)
- Nonpeptide covalent bonds
- Salt bridges
What is true regarding protein structure?
What is true regarding protein structure?
- Van der Waals interactions are insignificant
- Hydrophobic side chains are in the interior of the native protein (correct)
- Entropy is not a consideration when determining stability
- Hydrophilic side chains are never found in the interior
Why is there so little allowable rotation in the peptide bond?
Why is there so little allowable rotation in the peptide bond?
- The partial double bond character makes the peptide bond planar (correct)
- The R group prevents rotation about the peptide bond except for glycine
- Peptide bonds are amide bonds
- The C-N bond is shorter
- Peptide bonds are only formed in the cis configuration
What stabilizes the α helix?
What stabilizes the α helix?
What primarily stabilizes the β sheet?
What primarily stabilizes the β sheet?
Which is the more stable β sheet: parallel or antiparallel?
Which is the more stable β sheet: parallel or antiparallel?
Which statement regarding the tertiary structure of proteins is false?
Which statement regarding the tertiary structure of proteins is false?
What does denaturing followed by renaturing of a protein demonstrate?
What does denaturing followed by renaturing of a protein demonstrate?
What is needed for acid-base equilibrium concepts to be applied to amino acids, including titration curve, ionization states, and pI?
What is needed for acid-base equilibrium concepts to be applied to amino acids, including titration curve, ionization states, and pI?
What does the second law of thermodynamics state?
What does the second law of thermodynamics state?
What is the primary function of hemoglobin?
What is the primary function of hemoglobin?
Which type of bond is responsible for stabilizing the secondary structure of proteins such as alpha helices and beta sheets?
Which type of bond is responsible for stabilizing the secondary structure of proteins such as alpha helices and beta sheets?
What is the main function of myoglobin in muscle cells?
What is the main function of myoglobin in muscle cells?
What effect does 2,3-BPG have on hemoglobin's affinity for oxygen?
What effect does 2,3-BPG have on hemoglobin's affinity for oxygen?
In the context of protein-ligand binding, what does the term 'cooperativity' refer to?
In the context of protein-ligand binding, what does the term 'cooperativity' refer to?
Which type of bond is responsible for stabilizing the tertiary structure of a protein?
Which type of bond is responsible for stabilizing the tertiary structure of a protein?
What is the main function of antibodies in the immune system?
What is the main function of antibodies in the immune system?
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What is the primary role of buffers like glycine in biological systems?
What is the primary role of buffers like glycine in biological systems?
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