Podcast
Questions and Answers
What is the specialized integral membrane protein complex on cell surfaces that bind antigens recognized by lymphocytes?
What is the specialized integral membrane protein complex on cell surfaces that bind antigens recognized by lymphocytes?
- Antibody
- Glycoprotein
- Major Histocompatibility Complex (MHC) (correct)
- Transcription Factor
Which type of protein plays a crucial role in the immune rejection of grafted tissue or organs?
Which type of protein plays a crucial role in the immune rejection of grafted tissue or organs?
- MHC class I (correct)
- Enzyme
- Receptor
- Ribosome
What are the human cell counterparts of MHC class I and class II proteins often called?
What are the human cell counterparts of MHC class I and class II proteins often called?
- Kinases
- Hormones
- Human Leukocyte Antigens (HLAs) (correct)
- Immunoglobulins
What do T lymphocytes recognize on MHC proteins?
What do T lymphocytes recognize on MHC proteins?
Where are MHC molecules synthesized before they leave the cell?
Where are MHC molecules synthesized before they leave the cell?
What happens if the MHCs on cells of a tissue graft are not similar to those encountered by T lymphocytes during development?
What happens if the MHCs on cells of a tissue graft are not similar to those encountered by T lymphocytes during development?
What do T lymphocytes consider unfamiliar MHC epitopes on graft cells as?
What do T lymphocytes consider unfamiliar MHC epitopes on graft cells as?
Which organelles are involved in the production of MHC class I proteins?
Which organelles are involved in the production of MHC class I proteins?
What process do MHC class I proteins undergo before leaving the ER?
What process do MHC class I proteins undergo before leaving the ER?
What is the function of T lymphocytes towards cells with unfamiliar MHC epitopes on tissue grafts?
What is the function of T lymphocytes towards cells with unfamiliar MHC epitopes on tissue grafts?
Which cells display MHC class I molecules presenting self-antigens?
Which cells display MHC class I molecules presenting self-antigens?
Where are MHC class II proteins synthesized and transported to the cell surface?
Where are MHC class II proteins synthesized and transported to the cell surface?
What is the role of MHC class II proteins in antigen presentation?
What is the role of MHC class II proteins in antigen presentation?
What type of rejection occurs in homografts (allografts)?
What type of rejection occurs in homografts (allografts)?
Which type of graft involves identical twins?
Which type of graft involves identical twins?
Which cells are considered 'professional' antigen-presenting cells (APCs)?
Which cells are considered 'professional' antigen-presenting cells (APCs)?
What induces the transient expression of MHC class II on certain local cells during inflammation?
What induces the transient expression of MHC class II on certain local cells during inflammation?
Where do progenitors of B lymphocytes mature and differentiate further?
Where do progenitors of B lymphocytes mature and differentiate further?
What is the main function of stem cells in adults for all lymphocytes?
What is the main function of stem cells in adults for all lymphocytes?
What is the primary function of helper T cells?
What is the primary function of helper T cells?
Which surface proteins are involved in activating different responses to antigens for B and T cells?
Which surface proteins are involved in activating different responses to antigens for B and T cells?
How do cytotoxic T cells recognize antigens on foreign or virus-infected cells?
How do cytotoxic T cells recognize antigens on foreign or virus-infected cells?
What is the primary role of fibroblastic reticular cells in lymphoid tissue?
What is the primary role of fibroblastic reticular cells in lymphoid tissue?
Which type of lymphocytes bind antigens directly?
Which type of lymphocytes bind antigens directly?
What is the function of cytotoxic T lymphocytes (CTLs) when activated?
What is the function of cytotoxic T lymphocytes (CTLs) when activated?
Which lymphocytes are characterized by the presence of CD8?
Which lymphocytes are characterized by the presence of CD8?
What is the main function of fibrous reticulin fibers in lymphoid tissue?
What is the main function of fibrous reticulin fibers in lymphoid tissue?
How do T lymphocytes recognize antigenic epitopes?
How do T lymphocytes recognize antigenic epitopes?
What is the primary role of naive lymphocytes in newborn infants?
What is the primary role of naive lymphocytes in newborn infants?
Which cells release perforins and granzymes to trigger apoptosis?
Which cells release perforins and granzymes to trigger apoptosis?
What is the function of Regulatory T cells (Tregs)?
What is the function of Regulatory T cells (Tregs)?
Which type of T lymphocytes contain γ (gamma) and δ (delta) chains in their TCRs?
Which type of T lymphocytes contain γ (gamma) and δ (delta) chains in their TCRs?
Where do γδ T cells primarily migrate to in the body?
Where do γδ T cells primarily migrate to in the body?
What happens to B cells when BCRs bind an antigen?
What happens to B cells when BCRs bind an antigen?
What stimulates several cycles of cell proliferation in B lymphocytes?
What stimulates several cycles of cell proliferation in B lymphocytes?
What type of cells have long filamentous processes and interact with B lymphocytes in secondary lymphoid tissues?
What type of cells have long filamentous processes and interact with B lymphocytes in secondary lymphoid tissues?
What characterizes secondary nodules in secondary lymphoid tissues?
What characterizes secondary nodules in secondary lymphoid tissues?
What is the primary function of plasma cells derived from activated B cells?
What is the primary function of plasma cells derived from activated B cells?
How are memory B cells different from plasma cells?
How are memory B cells different from plasma cells?
