Lymphatic System Overview
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Questions and Answers

What are the two main components of the lymphatic system?

Lymphatic vessels & lymphatic tissues

What does lymph carry from the interstitial spaces to the blood?

  • Blood cells
  • Tissue fluid (correct)
  • Carbon dioxide
  • Oxygen

Lymphatic vessels have the same structure as blood vessels but have a smaller diameter.

False (B)

What are the aggregates of lymphocytes embedded in a network of reticular fibers called?

<p>Lymphatic tissues</p> Signup and view all the answers

Which of the following are lymphatic organs? (Select all that apply)

<p>Tonsils (A), Spleen (C), Thymus (D), Lymph nodes (E)</p> Signup and view all the answers

What is the shape of lymph nodes?

<p>Encapsulated spherical or kidney-shaped</p> Signup and view all the answers

What is the concave depression on a lymph node called?

<p>Hilum</p> Signup and view all the answers

Lymph nodes are only found in the head and neck.

<p>False (B)</p> Signup and view all the answers

What is the function of the stroma in a lymph node?

<p>Supportive connective tissue</p> Signup and view all the answers

Which of the following is part of the stroma of a lymph node? (Select all that apply)

<p>Capsule (A), Trabeculae (C), Reticular network (E)</p> Signup and view all the answers

What is the outermost layer of a lymph node?

<p>Capsule</p> Signup and view all the answers

What is the function of trabeculae in a lymph node?

<p>Divide the lymph node into incomplete compartments</p> Signup and view all the answers

What is the reticular network made up of?

<p>Reticular cells and reticular fibers</p> Signup and view all the answers

What are the two main parts of the parenchyma of a lymph node?

<p>Cortex and medulla</p> Signup and view all the answers

Which part of the cortex is located closer to the capsule?

<p>Outer cortex</p> Signup and view all the answers

The inner cortex is called the thymus-dependent area because it contains mostly T-lymphocytes.

<p>True (A)</p> Signup and view all the answers

What are the irregular spaces lined by discontinuous endothelial cells found in the cortex called?

<p>Cortical sinuses</p> Signup and view all the answers

Which of the following are types of cortical sinuses? (Select all that apply)

<p>Subcapsular sinuses (A), Paratrabecular sinuses (B)</p> Signup and view all the answers

Subcapsular sinuses are located between the capsule and the lymphatic follicles.

<p>True (A)</p> Signup and view all the answers

What are the cord-like structures in the medulla of a lymph node called?

<p>Medullary cords</p> Signup and view all the answers

What is the function of medullary sinuses in a lymph node?

<p>Connect the cortical sinuses with the efferent lymphatics</p> Signup and view all the answers

What are the two main functions of lymph nodes?

<p>Filtration of lymph and immunological function (D)</p> Signup and view all the answers

Lymph nodes are responsible for filtration of lymph from microorganisms.

<p>True (A)</p> Signup and view all the answers

Lymph nodes are only involved in cellular immunity.

<p>False (B)</p> Signup and view all the answers

What are the five main parts of the lymph circulation?

<p>Afferent lymphatic vessels, subcapsular sinuses, intermediate, paratrabecular sinuses, medullary sinuses, efferent lymphatic vessels</p> Signup and view all the answers

Which of the following is NOT a type of tonsil?

<p>Splenic (A)</p> Signup and view all the answers

Where are tonsils located?

<p>Beneath the mucous membrane of the mouth, pharynx and tongue</p> Signup and view all the answers

What type of tonsils are located in the lateral walls of the oropharynx?

<p>Palatine (D)</p> Signup and view all the answers

What are the invaginations of the stratified squamous epithelium in palatine tonsils called?

<p>Crypts</p> Signup and view all the answers

Palatine tonsils are fully encapsulated by a capsule.

<p>False (B)</p> Signup and view all the answers

What type of tissue separates the palatine tonsils from surrounding structures?

<p>Dense connective tissue</p> Signup and view all the answers

The palatine tonsils are covered by ______ epithelium.

<p>stratified squamous non-keratinized</p> Signup and view all the answers

Match the following labels of the palatine tonsil diagram with their corresponding structures:

<p>1 = Stratified squamous epithelium 2 = Lymphatic nodules 3 = Capsule 4 = Tonsillar crypts</p> Signup and view all the answers

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Flashcards

Lymphatic System

A complex network of vessels and tissues responsible for filtering fluids, transporting immune cells, and defending the body against pathogens.

Lymph

Fluid that circulates throughout the lymphatic system, derived from interstitial fluid and containing immune cells.

Lymph Nodes

Small, bean-shaped organs located throughout the body, acting as filters for lymph and sites for immune cell activation.

Lymph Node Structure

Encapsulated spherical or kidney-shaped organs, with a convex side for lymph entry and a concave hilum for exit.

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Lymph Node Stroma

A dense connective tissue encasing the lymph node, aiding in structural support and forming septa.

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Lymph Node Parenchyma

The functional tissue of the lymph node, containing lymphocytes, macrophages, and reticular fibers.

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Lymph Node Cortex

The outer region of the lymph node, featuring specialized structures called lymphatic follicles.

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Lymphatic Follicles

Compact clusters of lymphocytes in the lymph node cortex, where B-lymphocytes reside.

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Primary Lymphatic Follicles

Lymphatic follicles that have not yet encountered an antigen, containing primarily B-lymphocytes.

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Secondary Lymphatic Follicles

Lymphatic follicles exposed to an antigen, containing activated B-lymphocytes and a central germinal center.

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Germinal Center

A pale central area within secondary lymphatic follicles, characterized by proliferation of activated B-lymphocytes.

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Inner Cortex

The region between the outer and inner cortex of the lymph node, primarily containing T-lymphocytes.

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Cortical Sinuses

Irregular spaces lined by endothelial cells and reticular cells, connecting different parts of the lymph node.

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Lymph Node Medulla

The innermost region of the lymph node, containing medullary cords and sinuses.

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Medullary Cords

Linear structures in the lymph node medulla composed of lymphocytes and plasma cells.

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Medullary Sinuses

Spaces in the lymph node medulla that connect cortical sinuses with efferent lymphatics, allowing exit of lymph.

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Lymph Filtration

The process by which lymph nodes remove microorganisms and other debris from the lymphatic fluid.

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Lymphatic Immunological Function

The capacity of the lymphatic system to generate immune responses against pathogens and foreign substances.

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Lymph Circulation

The flow of lymph through the lymphatic system, from afferent vessels to efferent vessels.

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Afferent Lymphatic Vessels

Lymphatic vessels that carry lymph into a lymph node.

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Efferent Lymphatic Vessels

Lymphatic vessels that carry lymph out of a lymph node.

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Tonsils

Incomplete capsules of lymphoid tissue, located beneath mucous membranes of the mouth, pharynx, and tongue.

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Palatine Tonsils

Two tonsils located in the lateral walls of the oropharynx, playing a crucial role in immune defense.

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Palatine Tonsil Histological Structure

The microscopic structure of the palatine tonsils, characterized by secondary lymphatic follicles with germinal centers.

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Crypts

Invaginations of the epithelium into the lymphoid tissue of the palatine tonsils.

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Palatine Tonsil Capsule

A dense connective tissue surrounding the palatine tonsils, acting as a barrier against the spread of infection.

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Spleen

A large, vascular organ located in the left upper quadrant of the abdomen, acting as a filter for blood and reservoir for immune cells.

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Thymus

A bilobed organ located in the mediastinum, responsible for the maturation and differentiation of T-lymphocytes.

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Study Notes

Lymphatic System Overview

  • The lymphatic system is composed of lymphatic vessels and lymphatic tissues.
  • Lymphatic vessels carry lymph (tissue fluid) from interstitial spaces to the blood.
  • Lymphatic vessels have a similar structure to blood vessels but have a larger diameter and one blind end.
  • Lymphatic tissues contain aggregates of lymphocytes embedded in a network of reticular fibers.
  • Lymphatic tissues are organized into organs such as lymph nodes, spleen, thymus, and tonsils.

Lymph Nodes

  • Lymph nodes are encapsulated, spherical or kidney-shaped.
  • Lymph nodes have a convex side where afferent lymphatic vessels enter and a concave depression called the hilum where afferent vessels enter and veins and efferent vessels leave.
  • Lymph nodes are distributed along the course of lymphatic vessels.

Structure of Lymph Node

  • Stroma (Supportive Connective Tissue):
    • Capsule: a dense connective tissue layer thickened at the hilum.
    • Trabeculae: extensions of the capsule that divide the node into incomplete compartments.
    • Reticular network: composed of reticular cells and fibers.
  • Parenchyma:
    • Cortex: outer region
      • Outer cortex: contains lymphatic nodules (aggregations of lymphocytes, mostly B-cells).
      • Inner cortex: primarily T-lymphocytes, also known as the thymus-dependent area.
      • Cortical sinuses: irregular spaces lined by discontinuous endothelial cells and macrophages
        • Subcapsular sinuses: between capsule and lymphoid follicles
        • Paratrabecular sinuses: around trabeculae
    • Medulla: inner region
      • Medullary cords: composed of lymphocytes and plasma cells.
      • Medullary sinuses

Lymph Node Function

  • Lymph node function includes filtration of lymph to remove microorganisms and immunological function (both cellular and humoral immunity).
  • Lymph flows through the sinuses, trapping and removing foreign particles.
  • Lymph nodes are vital for immune responses. Lymphatic nodules in the cortex contain B-cells which differentiate into plasma cells in the presence of antigens.

Lymph Circulation

  • Lymph flows through the lymphatic vessels (afferent lymphatic vessels). It then flows through subcapsular sinuses->intermediate sinuses-> medullary sinuses. Finally it exits the node via efferent lymphatic vessels.

Tonsils

  • Tonsils are incompletely encapsulated aggregates of lymphatic tissue located beneath the mucous membrane of the mouth, pharynx, and tongue.
  • Types include palatine, pharyngeal, and lingual tonsils.
  • Palatine tonsils are paired tonsils found in the lateral walls of the oropharynx.
  • Histologically, tonsils are formed by lymphatic tissue containing secondary lymphatic follicles with germinal centres.
  • Lymphatic nodules are present under the epithelium; they are covered by stratified squamous non-keratinized epithelium forming crypts.
  • The crypts invaginate into the lymphoid tissue, and the dense connective tissue capsule acts as a barrier against infection.

Important Lymphocyte Locations

  • Lymph Node: T lymphocytes are largely found in the inner part of the cortex (thymus dependent area)
  • Lymph Node: B lymphocytes are mostly located in the outer cortex in aggregates called lymphatic nodules.
  • Spleen: contains both T and B lymphocytes

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Lymphatic System PDF 2025

Description

Explore the intricacies of the lymphatic system, including its vessels and tissues. This quiz covers the structure and function of lymph nodes as well as the roles of major lymphatic organs. Test your knowledge and deepen your understanding of this vital system in the body.

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