Lymphatic System
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Questions and Answers

Where does hematopoiesis and cell differentiation occur to generate all of the white blood cells?

  • Spleen red pulp
  • Lymph nodes paracortex
  • Bone marrow (correct)
  • Thymus medulla

    • Which structure is responsible for distinguishing between the cells and functions of the red and white pulp of the spleen?

  • Lymph nodes medulla
  • Lymph nodes follicle
  • Thymus medulla
  • Spleen follicle (correct)

    • What is the site of lymphatic drainage into the blood?

  • High endothelial venules
  • Efferent lymphatic vessels
  • Afferent lymphatic vessels
  • Thoracic duct (correct)

    • Which secondary lymphoid tissue is associated with immune cells and structural features?

    <p>Liver</p> Signup and view all the answers

    What is the role of high endothelial venules in immune cell trafficking?

    <p>Attracting immune cells to lymphoid tissues</p> Signup and view all the answers

    Where does osteopathic manipulative medicine affect the lymphatics and immunity?

    <p>Spleen red pulp</p> Signup and view all the answers

    Which method of manipulation is used by osteopathic physicians to increase the rate of lymph flow and reduce edema?

    <p>Abdominal LPT</p> Signup and view all the answers

    Where does the Right Lymphatic Duct empty into?

    <p>Right Subclavian Vein</p> Signup and view all the answers

    What do the Supratrochlear lymph nodes drain?

    <p>Upper arm and upper thoracic area</p> Signup and view all the answers

    Where do immune cells enter the lymph nodes from the tissues?

    <p>Afferent lymphatic vessels</p> Signup and view all the answers

    What are the functions of the liver?

    <p>All of the above</p> Signup and view all the answers

    Where are antigens presented in the liver?

    <p>Sinusoids</p> Signup and view all the answers

    What are the functions of the M cells in the Gut associated lymphoid tissue (GALT)?

    <p>Phagocytic and direct gut materials to follicles and lymph nodes</p> Signup and view all the answers

    What is the function of Bronchial associated lymphoid tissue in the lungs?

    <p>Surveys oro-pharynx for inhaled/ingested pathogens</p> Signup and view all the answers

    Where are commensal intestinal flora found?

    <p>Appendix</p> Signup and view all the answers

    What are the functions of Kupffer cells in the liver?

    <p>Remove antigens bound by antibodies</p> Signup and view all the answers

    What is the site of pus collection in the tonsils?

    <p>Palatine tonsils (back of the throat)</p> Signup and view all the answers

    What do thoracic ducts transport upwards to empty into?

    <p>Left Lymphatic Duct</p> Signup and view all the answers

    Where does hematopoiesis occur?

    <p>Red marrow</p> Signup and view all the answers

    What does the Common Myeloid Progenitor (CMP) produce?

    <p>Granulocytes, monocytes, red blood cells, and platelets</p> Signup and view all the answers

    Where can newly formed B cells enter and acquire a receptor?

    <p>Spleen</p> Signup and view all the answers

    What type of cells are localized in the white pulp of the spleen?

    <p>B and T cells</p> Signup and view all the answers

    What is the function of lymph nodes?

    <p>Filter lymph and generate an immune response against pathogens</p> Signup and view all the answers

    What aids in improving lymph flow?

    <p>Lymphatic pump and smooth muscle contractions</p> Signup and view all the answers

    Which site is responsible for iron transfer to erythroid progenitors?

    <p>Central macrophages in the bone marrow</p> Signup and view all the answers

    Where do hematopoietic stem cells differentiate into lymphoid and myeloid precursors?

    <p>Bone marrow</p> Signup and view all the answers

    What is the function of secondary lymphoid organs?

    <p>Storage, activation, and response to infection</p> Signup and view all the answers

    What is the primary function of primary lymphoid organs?

    <p>Immune cell birth and development</p> Signup and view all the answers

    What is the role of central macrophages in the bone marrow?

    <p>Facilitate iron transfer to erythroid progenitors</p> Signup and view all the answers

    Where do hematopoietic stem cells differentiate into lymphoid and myeloid precursors?

    <p>Bone marrow</p> Signup and view all the answers

    What facilitates iron transfer to erythroid progenitors?

    <p>Central macrophages in the bone marrow</p> Signup and view all the answers

    Where can newly formed B cells enter and acquire a receptor?

    <p>Spleen</p> Signup and view all the answers

    Which organ is responsible for production of blood cells and differentiation of immune cells?

    <p>Bone marrow</p> Signup and view all the answers

    Where are aged erythrocytes and pathogens filtered by macrophages?

    <p>Bone marrow</p> Signup and view all the answers

    What is the function of Red pulp in the spleen?

    <p>Filtering blood for antigens</p> Signup and view all the answers

    Which system collects and transports lymph into lymph nodes and the venous circulation?

    <p>Lymphatic system</p> Signup and view all the answers

    What helps in improving lymph flow?

    <p>Skeletal muscle contractions</p> Signup and view all the answers

    Where does osteopathic manipulative medicine primarily affect the lymphatics and immunity?

    <p>GALT</p> Signup and view all the answers

    What is the site of hematopoiesis and cell differentiation to generate all of the white blood cells?

    <p>Bone Marrow</p> Signup and view all the answers

    Which structure is responsible for distinguishing between the cells and functions of the red and white pulp of the spleen?

    <p>Central Artery</p> Signup and view all the answers

    What is the function of the high endothelial venules in immune cell trafficking?

    <p>Immune Cell Trafficking</p> Signup and view all the answers

    What do Kupffer cells primarily do in the liver?

    <p>Phagocytosis</p> Signup and view all the answers

    Where can newly formed B cells enter and acquire a receptor?

    <p>Bone Marrow</p> Signup and view all the answers

    What is the primary function of primary lymphoid organs?

    <p>Immune Cell Maturation</p> Signup and view all the answers

    Where do hematopoietic stem cells differentiate into lymphoid and myeloid precursors?

    <p>Bone Marrow</p> Signup and view all the answers

    What is the function of the abdominal lymphatic pump treatment?

    <p>To increase lymphatic flow</p> Signup and view all the answers

    Where does the Thoracic Duct empty into?

    <p>Left Lymphatic Duct</p> Signup and view all the answers

    Which site is responsible for bloodborne pathogen detection and antigen removal in the liver?

    <p>Sinusoids</p> Signup and view all the answers

    What is the primary function of Kupffer cells in the liver?

    <p>Capture and remove antigens from blood</p> Signup and view all the answers

    What is the role of M cells in the Gut Associated Lymphoid Tissue (GALT)?

    <p>Direct gut materials to lymph nodes</p> Signup and view all the answers

    Where are Bronchial Associated Lymphoid Tissue (BALT) found?

    <p>Lungs</p> Signup and view all the answers

    What is the main function of Peyer's Patches in the intestines?

    <p>Activate B cells to produce IgA antibodies</p> Signup and view all the answers

    What is the site of pus collection in tonsils?

    <p>Palatine tonsils</p> Signup and view all the answers

    What is the site of lymphatic drainage into the blood from the lower trunk and both legs?

    <p>Cisterna Chyli</p> Signup and view all the answers

    Study Notes

    • The immune system has two types of organs: primary and secondary

    • Primary lymphoid organs are sites of immune cell birth and development

    • Bone marrow is a primary lymphoid organ, where hematopoiesis occurs

    • Red marrow is the spongy portion of bone, where blood cells are produced

    • Yellow marrow is the fat storage part of bone marrow, present in adults

    • Hematopoietic stem cells differentiate into lymphoid and myeloid precursors in bone marrow

    • Common Lymphoid Progenitor (CLP) gives rise to lymphocytes, while Common Myeloid Progenitor (CMP) produces granulocytes, monocytes, red blood cells, and platelets

    • Central macrophages in the bone marrow facilitate iron transfer to erythroid progenitors

    • Aged erythrocytes and pathogens are filtered by macrophages in the bone marrow

    • Destinations for cells leaving the bone marrow include blood tissue, bone marrow, spleen, thymus, and lymph nodes

    • Secondary lymphoid organs are sites of immune cell storage, activation, and response to infection

    • Spleen is a secondary lymphoid organ, where newly formed B cells can enter and acquire a receptor

    • Red pulp in the spleen contains dendritic cells and macrophages that filter blood for antigens

    • White pulp, where B and T cells are localized, contains periarteriolar lymphoid sheaths and lymphoid follicles

    • Lymph nodes filter lymph and are compartmentalized, with different areas for naive B cells, follicular DC, activated B cells, T cells, and macrophages

    • Lymphatic system collects and transports lymph, which is a clear collection of fluid from the tissue, into lymph nodes and the venous circulation

    • Lymph nodes filter lymph and generate an immune response against pathogens

    • Valves in the lymphatics aid lymph flow, and mechanisms such as breathing, muscle contractions, and posture changes promote lymph movement

    • Lymphatic pump and smooth muscle contractions help in improving lymph flow

    • Damage to lymphatic tissue or nodes can result in swelling (edema) due to the accumulation of excess lymph.

    • The immune system has two types of organs: primary and secondary

    • Primary lymphoid organs are sites of immune cell birth and development

    • Bone marrow is a primary lymphoid organ, where hematopoiesis occurs

    • Red marrow is the spongy portion of bone, where blood cells are produced

    • Yellow marrow is the fat storage part of bone marrow, present in adults

    • Hematopoietic stem cells differentiate into lymphoid and myeloid precursors in bone marrow

    • Common Lymphoid Progenitor (CLP) gives rise to lymphocytes, while Common Myeloid Progenitor (CMP) produces granulocytes, monocytes, red blood cells, and platelets

    • Central macrophages in the bone marrow facilitate iron transfer to erythroid progenitors

    • Aged erythrocytes and pathogens are filtered by macrophages in the bone marrow

    • Destinations for cells leaving the bone marrow include blood tissue, bone marrow, spleen, thymus, and lymph nodes

    • Secondary lymphoid organs are sites of immune cell storage, activation, and response to infection

    • Spleen is a secondary lymphoid organ, where newly formed B cells can enter and acquire a receptor

    • Red pulp in the spleen contains dendritic cells and macrophages that filter blood for antigens

    • White pulp, where B and T cells are localized, contains periarteriolar lymphoid sheaths and lymphoid follicles

    • Lymph nodes filter lymph and are compartmentalized, with different areas for naive B cells, follicular DC, activated B cells, T cells, and macrophages

    • Lymphatic system collects and transports lymph, which is a clear collection of fluid from the tissue, into lymph nodes and the venous circulation

    • Lymph nodes filter lymph and generate an immune response against pathogens

    • Valves in the lymphatics aid lymph flow, and mechanisms such as breathing, muscle contractions, and posture changes promote lymph movement

    • Lymphatic pump and smooth muscle contractions help in improving lymph flow

    • Damage to lymphatic tissue or nodes can result in swelling (edema) due to the accumulation of excess lymph.

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    Description

    Test your knowledge of the lymphatic system and hematopoiesis with this quiz. Learn about the site of hematopoiesis, cell differentiation, functions of the red and white pulp of the spleen, and more.

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