Lymphatic System and Body Defenses Quiz
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Questions and Answers

Which lymphoid organ is responsible for the maturation of T cells?

  • Lymph nodes
  • Spleen
  • Thymus (correct)
  • Peyer's patches

What organ functions as a blood reservoir and stores platelets?

  • Spleen (correct)
  • Appendix
  • Thymus
  • Tonsils

Where are the tonsils primarily located in the body?

  • Kidneys
  • Throat (pharynx) (correct)
  • Lungs
  • Stomach

What component of the first line of defense offers protection against harmful bacteria present in raw chicken meat?

<p>Acid mantle (C)</p> Signup and view all the answers

How do natural killer (NK) cells primarily protect the body?

<p>Promote cell lysis (B)</p> Signup and view all the answers

Which statement best defines the body's first line of defense against pathogens?

<p>Skin and mucous membranes (B)</p> Signup and view all the answers

What effect does an antihistamine have on the inflammatory response?

<p>Prevents swelling and redness (D)</p> Signup and view all the answers

Which of the following is NOT considered a nonspecific body defense?

<p>Antibody production (C)</p> Signup and view all the answers

Which antibody is mainly found in secretions like tears and saliva?

<p>IgA (B)</p> Signup and view all the answers

What is the primary role of IgE in the immune response?

<p>Allergic responses (A)</p> Signup and view all the answers

Which option describes how the body primarily addresses cellular antigens?

<p>Complement fixation (B)</p> Signup and view all the answers

What occurs when a foreign blood type is transfused and causes clumping?

<p>Agglutination (A)</p> Signup and view all the answers

What term is used for the blockage of bacterial exotoxins by antibodies?

<p>Neutralization (A)</p> Signup and view all the answers

Which immune cells are activated through antigen presentation?

<p>Helper T cells (D)</p> Signup and view all the answers

What type of T cell is primarily responsible for releasing cytokines to help fight antigens?

<p>Helper T cells (B)</p> Signup and view all the answers

Which type of graft is least likely to succeed in a kidney transplant?

<p>Xenograft (A)</p> Signup and view all the answers

What provides immunity against disease through the injection of serum containing antibodies?

<p>Passive immunity (C)</p> Signup and view all the answers

Which type of cells are responsible for developing immunocompetence before responding to specific antigens?

<p>Lymphocytes (A)</p> Signup and view all the answers

Humoral immunity is primarily provided by which component in the body?

<p>Antibodies (C)</p> Signup and view all the answers

Which statement accurately describes the role of T lymphocytes (T cells)?

<p>T cells activate other lymphocytes. (D)</p> Signup and view all the answers

What determines the specific foreign substances that an immune system can recognize and resist?

<p>Genetic makeup (B)</p> Signup and view all the answers

The development of self-tolerance is critical for the functioning of which type of cells?

<p>Both A and B (D)</p> Signup and view all the answers

Where does the development of B cells' immunocompetence primarily take place?

<p>Bone marrow (D)</p> Signup and view all the answers

Which cells primarily mediate the adaptive immune response?

<p>T cells (B)</p> Signup and view all the answers

Which of the following statements is false regarding the immune system?

<p>Antibodies are solely responsible for cell-mediated immunity. (D)</p> Signup and view all the answers

Which component is NOT one of the main structures of the lymphatic system?

<p>Tissues (B)</p> Signup and view all the answers

Which statement about lymph nodes is correct?

<p>They filter bacteria and viruses from lymph, not blood. (B)</p> Signup and view all the answers

What is the primary role of the spleen in the lymphatic system?

<p>Site for lymphocyte proliferation and immune surveillance (D)</p> Signup and view all the answers

What is the primary function of the thymus gland?

<p>T cell maturation (D)</p> Signup and view all the answers

Which of the following statements regarding lymphocytes is true?

<p>B cells are responsible for antibody production. (B)</p> Signup and view all the answers

Which cell type enables a quick immune response upon subsequent exposure to the same antigen?

<p>Memory cell (B)</p> Signup and view all the answers

Which of the following best describes mechanical barriers in the immune system?

<p>They consist of physical defenses like skin and mucous membranes. (D)</p> Signup and view all the answers

What is the function of the regulatory T cell in the immune response?

<p>Slow or stop B and T cell activity (B)</p> Signup and view all the answers

What term describes the process by which complement proteins attach to foreign cell surfaces?

<p>Complement fixation (C)</p> Signup and view all the answers

Which cell type is responsible for producing large quantities of antibodies?

<p>Plasma cell (D)</p> Signup and view all the answers

What role does the cytotoxic T cell play in the immune system?

<p>Kill virus-infected and cancerous cells (D)</p> Signup and view all the answers

Which of the following is a characteristic function of antigen-presenting cells?

<p>Engulf and present parts of antigens (A)</p> Signup and view all the answers

Which cell type undergoes development of immunocompetence in the bone marrow?

<p>B cell (C)</p> Signup and view all the answers

What is the primary function of helper T cells in the immune response?

<p>Recruit and activate other immune cells (B)</p> Signup and view all the answers

After an infection, which cell type aids in terminating the immune response?

<p>Regulatory T cell (B)</p> Signup and view all the answers

What occurs when soluble antigenic molecules become insoluble and settle out of solution?

<p>Precipitation (C)</p> Signup and view all the answers

During the primary humoral response, what happens to B cells that do not become plasma cells?

<p>They become memory cells. (A)</p> Signup and view all the answers

What is a major function of antigen-presenting cells (APCs) in the immune response?

<p>To engulf antigens and present them to T cells. (B)</p> Signup and view all the answers

How does the secondary humoral response differ from the primary humoral response?

<p>It is more prolonged and effective due to pre-existing memory cells. (A)</p> Signup and view all the answers

What does the destruction of cilia in the lungs primarily increase the risk of?

<p>Respiratory infections. (D)</p> Signup and view all the answers

What type of immunity is primarily facilitated by T cell clones?

<p>Cell-mediated immunity (D)</p> Signup and view all the answers

What structural damage do cilia protect against?

<p>Bacterial growth in the lungs (C)</p> Signup and view all the answers

What happens to the immune response without activated antigen-presenting cells?

<p>It is severely impaired. (D)</p> Signup and view all the answers

Flashcards

What lymphoid organ stores platelets and acts as a blood reservoir?

The spleen is responsible for storing platelets and serving as a blood reservoir, filtering blood, and removing old or damaged red blood cells.

Where are the tonsils located?

The tonsils are located in the throat (pharynx), specifically at the entrance of the respiratory and digestive tracts.

Acid mantle

The acid mantle is a protective layer of slightly acidic sebum and sweat on the skin's surface that helps inhibit bacterial growth.

How do natural killer (NK) cells protect the body?

Natural killer (NK) cells directly target and destroy infected cells and cancer cells by releasing cytotoxic substances that induce cell lysis (bursting).

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What is the body's first line of defense against the invasion of disease-causing microorganisms?

The body's first line of defense against invading pathogens is the skin and mucous membranes. These act as physical barriers and secrete substances that inhibit microbial growth.

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What does an antihistamine prevent?

An antihistamine prevents the release or action of histamine, a chemical released during an allergic reaction, which is the primary cause of redness and swelling in the inflammatory response.

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What is the inflammatory response?

The inflammatory response is a nonspecific immune response that involves redness, swelling, heat, and pain. It helps to isolate and destroy pathogens, while promoting tissue healing.

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Nonspecific body defenses

Nonspecific body defenses are a broad range of mechanisms that protect the body from a wide variety of pathogens without targeting specific ones. Examples include intact skin, mucous membranes, the inflammatory response, fever, natural killer cells, and antimicrobial proteins.

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Adaptive Immunity

The body's specific defense system that recognizes and targets particular pathogens or foreign substances. It provides long-lasting immunity to specific threats.

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Humoral Immunity

A type of adaptive immunity involving antibodies present in bodily fluids (like blood and lymph) that neutralize pathogens.

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Cell-Mediated Immunity

A type of adaptive immunity that utilizes T lymphocytes (T cells) to directly attack and destroy infected cells or pathogens.

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Lymphocytes

White blood cells that develop immunocompetence, meaning they can recognize and respond to specific antigens.

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Antigens

Specific molecules, usually proteins or carbohydrates, on the surface of pathogens or foreign substances that the immune system recognizes and responds to.

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Self-Tolerance

The immune system's ability to distinguish between its own cells (self) and foreign cells (non-self) to avoid attacking its own tissues.

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Immunocompetence

The ability of lymphocytes to recognize and respond to specific antigens, acquired during development.

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B Cell Development

B cells gain immunocompetence (ability to recognize specific antigens) within the bone marrow.

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Lymphatic System Structures

The lymphatic system consists of lymphatic vessels and lymph nodes, responsible for fluid balance, immune function, and lipid absorption.

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Lymph Circulation

Lymph fluid travels through lymphatic vessels and eventually rejoins the bloodstream through the subclavian veins.

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Lymph Node Function

Lymph nodes filter bacteria, viruses, and tumor cells from lymph fluid, which is a fluid similar to blood but clear.

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Spleen Function

The spleen is a vital part of the lymphatic system. It filters blood, stores white blood cells, and removes old red blood cells.

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Thymus Function

The thymus gland is where T cells, a type of white blood cell, mature and develop immune competence.

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Adaptive Immune System

The adaptive immune system is a specific defense mechanism that targets specific pathogens and remembers them for future encounters.

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Innate Immune System

The innate immune system provides a non-specific defense against pathogens and is the body's first line of defense.

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Antibody Production

While all lymphocytes are involved in the immune response, only B cells produce antibodies, which are proteins that target specific antigens.

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Precipitation in Immunity

When soluble antigens become insoluble and settle out of solution, this process is called precipitation. It enhances phagocytosis by making the antigens easier to capture.

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Primary Humoral Response

The initial immune response to an antigen. It involves B cell activation, proliferation, and differentiation into plasma cells that secrete antibodies. Some B cells become memory cells.

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Secondary Humoral Response

The immune response to a previously encountered antigen. It is faster, stronger, and more effective than the primary response due to the presence of memory cells.

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Antigen-Presenting Cells (APCs)

Cells that engulf antigens and present fragments of them on their surface, along with their own MHC molecules, for recognition by T cells. They are crucial for initiating adaptive immune responses.

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Immune System's First Line of Defense

The initial barrier against pathogens, which includes physical barriers like skin and mucous membranes, along with chemical factors like antimicrobial peptides.

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Cilia in Respiratory System

Hair-like projections that line the airways, sweeping mucus containing trapped dust and bacteria upwards towards the mouth, preventing them from entering the lungs.

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Mucus in Respiratory System

A sticky substance that traps dust, bacteria, and other harmful particles in the airways, preventing them from reaching the lungs.

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Impact of Damaged Cilia

Damaged or destroyed cilia lead to increased risk of infections in the respiratory system, as they are less effective at removing inhaled particles and pathogens.

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What is the role of regulatory T cells?

Regulatory T cells (Tregs) are a type of T lymphocyte that suppress or inhibit the activity of other immune cells, like B cells and T cells, once an infection has been cleared.

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What is a plasma cell?

A plasma cell is a type of B lymphocyte that produces large amounts of a specific antibody, or immunoglobulin, in response to an antigen.

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What is a cytotoxic T cell?

Cytotoxic T cells (CTLs) are a type of T lymphocyte that directly kill infected cells, such as those infected with viruses, cancer cells, or cells from a foreign organ transplant.

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What does an antigen-presenting cell (APC) do?

An antigen-presenting cell (APC) is a type of immune cell that engulfs and processes antigens (foreign substances), presenting fragments of them on its surface for recognition by T cells.

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What is the role of a memory cell?

A memory cell is a type of lymphocyte (B or T cell) that persists in the body for a long time, ready to quickly mount an immune response if the same antigen is encountered again.

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What is the function of a helper T cell?

Helper T cells (Th cells) play a crucial role in coordinating the adaptive immune response by activating other immune cells, such as B cells and cytotoxic T cells, to fight off infection.

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How is lymph formed?

Lymph is formed from blood plasma that leaks out of capillaries into the surrounding tissues, becoming interstitial fluid. This fluid is then collected by lymphatic capillaries, which then begin transporting it as lymph.

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What is the consequence of lymph node removal?

Removal of lymph nodes can lead to edema (swelling) in the affected area because the lymph nodes are responsible for draining excess interstitial fluid from the tissues. With their removal, the fluid can accumulate, causing swelling.

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IgE Antibody

An antibody primarily involved in allergic reactions. It binds to allergens and triggers the release of histamine from mast cells, leading to symptoms like sneezing, itching, and inflammation.

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IgG Antibody

The most abundant antibody in blood plasma, providing long-lasting immunity. It can cross the placenta, protecting the fetus. IgG is responsible for neutralizing toxins, viruses, and bacteria, and it can activate complement.

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IgM Antibody

The first antibody produced during a primary immune response. IgM exists as a pentamer (five units) and has the highest binding capacity. It activates complement and is involved in agglutination.

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Complement Fixation

A process where antibodies bind to antigens on the surface of pathogens, activating complement proteins. Complement proteins then initiate a cascade of reactions that lead to the lysis (destruction) of the pathogen.

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Agglutination

The clumping together of antigens by antibodies. This occurs when multiple antibodies bind to multiple antigens on the surface of pathogens, leading to their inactivation and clearance from the body.

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Neutralization

The process where antibodies bind to and block the active sites of pathogens, preventing them from interacting with host cells and causing harm. This is a key mechanism of defense against toxins and viruses.

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Helper T Cells

A type of T cell that helps activate other immune cells. Helper T cells release cytokines, which act as signaling molecules to stimulate B cells to produce antibodies and cytotoxic T cells to destroy infected cells.

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Xenograft

A graft that involves transplanting tissue or organs from a different species to a recipient. This type of graft is the least successful because of significant immune rejection due to major differences in antigens between species.

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Study Notes

Lymphatic System and Body Defenses

  • The lymphatic system is crucial for fluid balance and immunity
  • Lymph capillaries absorb interstitial fluid and return it to the blood
  • Lymph nodes filter lymph, trapping pathogens and immune cells
  • The spleen filters blood, removing old red blood cells and pathogens
  • The thymus is vital for T cell maturation, crucial for an adaptive immune response
  • Peyer's patches are located in the small intestine and help filter pathogens
  • Tonsils filter pathogens entering the throat
  • Lymphatic collecting vessels, small vessels that transport lymph, return lymph to the blood.
  • Lymph capillaries have flap-like mini valves to prevent backflow, are characterized by the presence of flap-like mini valves, and consistently operate under high pressure.
  • Lymph nodes are located along lymphatic vessels and filter lymph

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Test your knowledge on the lymphatic system and its role in body defenses. This quiz covers essential functions of lymph organs, the flow of lymph, and the immune response mechanisms. Challenge yourself and learn about the intricacies of immunity!

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