Podcast
Questions and Answers
What is the principal inducer of T-dependent responses in the immune system?
What is the principal inducer of T-dependent responses in the immune system?
- Macrophages
- B cells
- Dendritic cells (correct)
- Natural killer cells
Which cell type expresses high levels of MHC molecules and costimulators, making it the most potent APC for activating naive T lymphocytes?
Which cell type expresses high levels of MHC molecules and costimulators, making it the most potent APC for activating naive T lymphocytes?
- Dendritic cells (correct)
- B cells
- Natural killer cells
- Macrophages
What type of cell accumulates at sites of infection in innate immune responses and is important for effector T cells, especially of the helper T cell lineage?
What type of cell accumulates at sites of infection in innate immune responses and is important for effector T cells, especially of the helper T cell lineage?
- B cells
- Macrophages (correct)
- Dendritic cells
- Natural killer cells
What type of cells are capable of migrating to lymph nodes, where they encounter naive T cells poised to recognize antigens?
What type of cells are capable of migrating to lymph nodes, where they encounter naive T cells poised to recognize antigens?
Study Notes
Antigen-Presenting Cells (APCs)
- Dendritic cells are the principal inducer of T-dependent responses in the immune system.
- Dendritic cells express high levels of MHC molecules and costimulators, making them the most potent APC for activating naive T lymphocytes.
Innate Immune Response
- Neutrophils accumulate at sites of infection in innate immune responses and are important for effector T cells, especially of the helper T cell lineage.
Antigen Presentation
- Dendritic cells are capable of migrating to lymph nodes, where they encounter naive T cells poised to recognize antigens.
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Description
Explore the process of how protein antigens of microbes are transported and concentrated in the regions of the lymph nodes, where they are likely to encounter T lymphocytes. Understand the role of dendritic cells and naive T cells in this process.
