18 Questions
What is the main function of Th1 subset of CD4+ T-cells?
Combat intracellular microbes
What is the effect of cytokines produced by APCs on macrophages?
Activate macrophages to eliminate intracellular microbes
What is the primary function of macrophages in the immune response?
Combat intracellular microbes
What is the primary role of follicular helper T-cells?
Produce antibodies against pathogens
What is the role of ILC1 and ILC3 in the immune response?
Provide immediate defense against infection
What is the effect of TNF-α on the immune response?
Induce inflammation and tissue damage
What is the role of S1P receptors in T-cell activation?
Regulating T-cell migration
What is the outcome of T-cell activation in lymph nodes?
Clonal expansion
What is the function of high endothelial venules in lymph nodes?
T-cell migration
Which molecule is responsible for the egression of T-cells from lymph nodes?
S1P
What is the consequence of blocking S1P receptors in T-cells?
Reduced T-cell migration
What is the potential outcome of dysregulated T-cell activation in autoimmune diseases?
Uncontrolled T-cell proliferation
Which type of T-cells is primarily involved in autoimmune responses?
Th1
Which of the following cytokines is associated with Th2 responses?
IL-4
What is the primary function of CD8+ cells?
Cytotoxicity
What is the primary mechanism of action of Th1 cells?
Activation of macrophages
Which of the following is a characteristic of Th2 responses?
Production of IgE antibodies
What is the primary function of antigen-presenting cells (APCs)?
Antigen presentation
This quiz covers the functions of lymph nodes, including the role of dendritic cells, lymphocyte activation, and the process of T-cell egression. It also explores the receptors and ligands involved in these processes. Test your knowledge of lymph node biology and the immune system!
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
