Podcast
Questions and Answers
What is a common constitutional symptom of SLE?
What is a common constitutional symptom of SLE?
Which of the following is a diagnostic criterion for SLE?
Which of the following is a diagnostic criterion for SLE?
What is a medication used to treat SLE?
What is a medication used to treat SLE?
What is a risk factor for developing SLE?
What is a risk factor for developing SLE?
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What is a symptom of lupus nephritis?
What is a symptom of lupus nephritis?
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What is a diagnostic test for lupus nephritis?
What is a diagnostic test for lupus nephritis?
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What is a lifestyle modification that can help manage SLE?
What is a lifestyle modification that can help manage SLE?
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What is a treatment for lupus nephritis?
What is a treatment for lupus nephritis?
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Study Notes
Symptoms
- ** Constitutional symptoms **:
- Fatigue
- Fever
- Weight loss
-
Skin symptoms:
- Butterfly-shaped rash on the face (malar rash)
- Rashes on the arms, legs, and body
- Skin lesions
- Photosensitivity
-
Joint symptoms:
- Joint pain and swelling
- Arthritis
-
Neurological symptoms:
- Headaches
- Seizures
- Psychosis
- Cognitive impairment
-
Other symptoms:
- Hair loss
- Mouth sores
- Swollen lymph nodes
Diagnosis
-
Diagnostic criteria:
- American College of Rheumatology (ACR) criteria
- Systemic Lupus International Collaborating Clinics (SLICC) criteria
-
Laboratory tests:
- Complete blood count (CBC)
- Erythrocyte sedimentation rate (ESR)
- Antinuclear antibody (ANA) test
- Anti-double-stranded DNA (anti-dsDNA) antibody test
- Anti-Smith (anti-Sm) antibody test
-
Imaging tests:
- X-rays
- Ultrasound
- MRI
Treatment Options
-
Medications:
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Corticosteroids
- Immunosuppressive drugs
- Antimalarials
- Biologics
-
Lifestyle modifications:
- Sun protection
- Regular exercise
- Stress management
- Healthy diet
-
Alternative therapies:
- Acupuncture
- Massage therapy
- Yoga
Causes And Risk Factors
-
Genetic factors:
- Family history
- Genetic mutations
-
Environmental factors:
- UV light exposure
- Smoking
- Hormonal changes
- Infections
-
Immune system dysfunction:
- Abnormal immune response
- Autoantibody production
-
Demographic factors:
- Female gender
- African American or Hispanic ethnicity
- Age (15-45 years)
Lupus Nephritis
-
Definition:
- Inflammation of the kidneys due to SLE
-
Symptoms:
- Hematuria (blood in the urine)
- Proteinuria (excess protein in the urine)
- Edema
- Hypertension
-
Diagnosis:
- Urinalysis
- Kidney biopsy
-
Treatment:
- Corticosteroids
- Immunosuppressive drugs
- Blood pressure control
- Dialysis or kidney transplantation in severe cases
Symptoms
- Constitutional symptoms include fatigue, fever, and weight loss
- Skin symptoms include butterfly-shaped rash on the face, rashes on arms, legs, and body, skin lesions, and photosensitivity
- Joint symptoms include joint pain and swelling, and arthritis
- Neurological symptoms include headaches, seizures, psychosis, and cognitive impairment
- Other symptoms include hair loss, mouth sores, and swollen lymph nodes
Diagnosis
- Diagnostic criteria include ACR and SLICC criteria
- Laboratory tests include CBC, ESR, ANA, anti-dsDNA, and anti-Sm tests
- Imaging tests include X-rays, ultrasound, and MRI
Treatment Options
- Medications include NSAIDs, corticosteroids, immunosuppressive drugs, antimalarials, and biologics
- Lifestyle modifications include sun protection, regular exercise, stress management, and a healthy diet
- Alternative therapies include acupuncture, massage therapy, and yoga
Causes And Risk Factors
- Genetic factors include family history and genetic mutations
- Environmental factors include UV light exposure, smoking, hormonal changes, and infections
- Immune system dysfunction includes abnormal immune response and autoantibody production
- Demographic factors include female gender, African American or Hispanic ethnicity, and age between 15-45 years
Lupus Nephritis
- Definition: Inflammation of the kidneys due to SLE
- Symptoms include hematuria, proteinuria, edema, and hypertension
- Diagnosis involves urinalysis and kidney biopsy
- Treatment includes corticosteroids, immunosuppressive drugs, blood pressure control, and dialysis or kidney transplantation in severe cases
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Description
This quiz covers the symptoms and diagnostic criteria of lupus, a chronic autoimmune disease. It includes constitutional, skin, joint, neurological, and other symptoms as well as diagnostic criteria.
