Lung Volumes and Capacities

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Questions and Answers

Which of the following is NOT a direct measurement obtained using a spirometer?

  • Tidal Volume
  • Expiratory Reserve Volume
  • Inspiratory Capacity
  • Residual Volume (correct)

A patient's functional residual capacity (FRC) is determined to be significantly higher than normal. This increase could be attributed to an increase in which of the following?

  • Tidal Volume
  • Expiratory Reserve Volume or Residual Volume (correct)
  • Inspiratory Reserve Volume
  • Inspiratory Capacity

In a pulmonary function test, a patient exhibits a normal vital capacity but a significantly reduced forced expiratory volume in 1 second (FEV1). This pattern is most indicative of which type of respiratory condition?

  • Normal Lung Function
  • Obstructive Lung Disease (correct)
  • Restrictive Lung Disease
  • Combined Restrictive and Obstructive Disease

Which of the following volumes or capacities is the sum of the tidal volume and the inspiratory reserve volume?

<p>Inspiratory Capacity (IC) (D)</p> Signup and view all the answers

A patient has a pulmonary disorder that affects their ability to fully exhale. Which of the following lung volumes would likely be increased above normal in this patient?

<p>Residual Volume (C)</p> Signup and view all the answers

A researcher is using helium dilution to measure a patient's residual volume. If the initial concentration of helium is known, what other measurement is essential for calculating the residual volume using the dilution equation?

<p>Final concentration of Helium (D)</p> Signup and view all the answers

Which of the following best describes the relationship between airway resistance and surface area within the lungs?

<p>Resistance is inversely proportional to the square of the surface area. (D)</p> Signup and view all the answers

A patient presents with shortness of breath and a persistent cough. Pulmonary function tests reveal a FEV1/FVC ratio of 85%, which is considered normal. However, both FEV1 and FVC are below normal limits. Which condition is most consistent with these findings?

<p>Restrictive Lung Disease (D)</p> Signup and view all the answers

In the context of pulmonary function, what does the term 'capacity' refer to?

<p>The sum of two or more lung volumes. (B)</p> Signup and view all the answers

According to the material, approximately how much air remains in the lungs, even after maximum expiration?

<p>1.1 L (D)</p> Signup and view all the answers

In a patient with emphysema, which of the following compensatory mechanisms would help to maintain adequate pulmonary blood flow?

<p>Increased pulmonary artery pressure (A)</p> Signup and view all the answers

If a patient's FEV1 improves significantly after administration of a bronchodilator, what does this indicate about their airway obstruction?

<p>The obstruction is reversible. (D)</p> Signup and view all the answers

In the context of pulmonary function tests, what is the significance of anthropometric variables?

<p>They help predict the expected results for a person with similar traits. (C)</p> Signup and view all the answers

Which of the following statements is most accurate regarding the relationship between forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) in obstructive and restrictive lung diseases?

<p>FEV1/FVC is decreased in obstructive diseases and normal or increased in restrictive diseases (C)</p> Signup and view all the answers

What is the primary reason why helium is used in the gas dilution method for determining residual volume?

<p>Helium is a noble gas and does not readily interact with other gases. (B)</p> Signup and view all the answers

A patient presents with a history of smoking and is diagnosed with Cor Pulmonale. Which of the following best describes the underlying mechanism leading to this condition?

<p>Right ventricular dilation due to lung disease (D)</p> Signup and view all the answers

A person has a tidal volume of 500 ml, an inspiratory reserve volume of 2500 ml, and an expiratory reserve volume of 1000 ml. What is their vital capacity?

<p>4000 ml (C)</p> Signup and view all the answers

A patient exhibits an increased residual volume and a normal total lung capacity. Which of the following is the most likely cause of these findings?

<p>Obstructive Lung Disease (B)</p> Signup and view all the answers

Following prolonged exposure to cigarette smoke, a patient develops emphysema. What is the primary pathological change that leads to the decreased surface area for gas exchange in this condition?

<p>Destruction of the alveolar walls (C)</p> Signup and view all the answers

In a patient with a known respiratory condition, pulmonary function tests show a FEV1/FVC ratio of less than 0.7. Which of the following staging classifications of COPD could the patient potentially have?

<p>Any of the above (D)</p> Signup and view all the answers

Flashcards

Spirometer

Apparatus for measuring the volume of air inspired/expired by the lungs.

Residual volume

The volume of gas remaining in the lungs after a maximum expiration.

Lung Capacities

Lung measurements that are the sum of two or more lung volumes.

Tidal Volume

Amount of gas inhaled/exhaled during an unforced respiratory cycle

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Functional Residual Capacity (FRC)

The amount of volume in the lungs after normal expiration.

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Inspiratory Reserve Volume (IRV)

The amount of additional air one can forcefully inhale exceeding tidal volume.

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Inspiratory Capacity (IC)

Volume forcefully inhaled after expiration.

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Expiratory Reserve Volume

Volume that can be forcefully expired until you no longer can.

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Residual Volume (RV)

Air that stays in the lungs, no matter what.

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Vital Capacity (VC)

All volumes and capacities except the residual volume.

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Total Lung Capacity (TLC)

As the name implies, it includes everything.

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FEV1

A volume of air expired in the first second during maximal expiratory effort.

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FVC

The volume of air exhaled with maximal effort.

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Reversible obstruction

The obstruction can be reversed with medication.

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Irreversible obstruction

The walls and capillaries surrounding each alveoli are destroyed and merge together.

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Cor pulmonale

Right ventricular dilation due to lung disease.

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Study Notes

Lung Diseases and Spirometry

  • Spirometer is used for measuring the volume of inspired and expired air
  • Before inhaling, there is approximately 2.2L of air already in the lungs

Lung Volumes and Capacities

  • Table 16.3 is important to memorise
  • Spirometer cannot measure residual volume or capacities requiring residual volume for calculation
  • The spirometer only measures inspired and expired air

Capacities

  • Capacities consists of two or more volumes
  • Tidal Volume (Vt): Air volume per inspiration or expiration; approximately 500ml
  • Functional Residual Capacity (FRC): Volume in lungs after normal expiration/before normal inspiration; approximately 2200ml
  • Inspiratory Reserve Volume (IRV): Extra air volume forcefully inhaled exceeding tidal volume
  • Inspiratory Capacity (IC): Air volume forcefully inhaled after expiration, from 2.2L mark to 6L
  • Expiratory Reserve Volume (ERV): Air volume forcefully expired until impossible, residual volume remains
  • Residual Volume (RV): Air volume remaining in lungs, approximately 1.1L
  • Vital Capacity (VT): All volumes and capacities except residual volume
  • Total Lung Capacity: Includes all volumes
  • Spirometer is incapable of measuring residual volume, therefore all formulas that include it remain unknown
  • Residual volume can be found by using helium gas dilution methods
  • The common dilution equation is C1V1=C2V2

Pulmonary Function Tests (PFT)

  • Pulmonary Function Test (PFT): Focuses on volumes and capacity
  • Kidney Function Test (KFT): Measures urea and creatinine
  • Liver Function Test (LFT): Measures enzymes
  • PFTs require anthropometric variables (name, age, gender, weight, height) to determine the expected result
  • Results depend on these variables; deviations may indicate problems

PFT Test Example

  • Here is a PFT test for a 75Kg male, 170cm tall
PREDICTED OBSERVED OBSERVED/PREDICTED
FEV1.0 4 4L 100%
FEV1.0 (with obstructive diseases, eg: emphysema & COPD) 4 3 75%
FEV1.0 (with constricted lungs, eg: fibrosis & RDS) 4 4.5 110%
FVC 5 5 100%
FEV1.0/FVC 80% 70%

COPD Staging

  • 80%= normal

  • 60-80%= mild
  • 40-60%= moderate
  • <40%= severe COPD

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