Lung Abscess: Causes and Complications

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Questions and Answers

What is the primary characteristic of lung abscess formation?

  • Permanent enlargement of the air spaces distal to the terminal bronchioles
  • Granulomatous inflammation
  • Localized area of suppurative necrosis within the pulmonary parenchyma (correct)
  • Chronic pneumonia with regional lymph node involvement

Which of the following organisms is NOT a common cause of lung abscess?

  • Streptococcus pyogenes
  • Mycobacterium tuberculosis
  • Pseudomonas spp.
  • Escherichia coli (correct)

What is a common clinical feature of chronic pneumonia?

  • Regional lymph node involvement
  • Copious amounts of foul-smelling sputum
  • Hemoptysis
  • Granulomatous inflammation (correct)

What is the primary difference between pneumonia in immunocompetent individuals and those with immunocompromised hosts?

<p>The severity of symptoms (D)</p> Signup and view all the answers

Which of the following fungi is a common cause of pneumonia in immunocompromised hosts?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary characteristic of emphysema?

<p>Permanent enlargement of the air spaces distal to the terminal bronchioles (B)</p> Signup and view all the answers

How many types of emphysema are classified according to anatomic distribution?

<p>4 (B)</p> Signup and view all the answers

What is the primary difference between lung abscess and chronic pneumonia?

<p>The presence of cavities within the pulmonary parenchyma (B)</p> Signup and view all the answers

What is the primary mechanism by which smoking-related carcinomas of the lung arise?

<p>Through a stepwise accumulation of driver mutations (A)</p> Signup and view all the answers

What is the primary difference between adenocarcinomas and squamous cell carcinomas in terms of their location?

<p>Adenocarcinomas are more peripherally located, while squamous cell carcinomas are more centrally located (C)</p> Signup and view all the answers

What is the primary characteristic of squamous cell carcinomas in terms of their growth rate and metastasis?

<p>They grow slowly and metastasize early (B)</p> Signup and view all the answers

What is the primary association between adenocarcinomas and specific demographics?

<p>Adenocarcinomas are more common in women and never-smokers (C)</p> Signup and view all the answers

What is the primary effect of passive smoking on the risk of developing lung cancer?

<p>It increases the risk of developing lung cancer, but only modestly (B)</p> Signup and view all the answers

What is the primary characteristic of squamous cell carcinomas in terms of their morphological features?

<p>They form large cavities through central necrosis (A)</p> Signup and view all the answers

What is the primary precursor lesion to squamous cell carcinoma?

<p>Squamous metaplasia or dysplasia in the bronchial epithelium (B)</p> Signup and view all the answers

What is the primary difference between the dissemination patterns of squamous cell carcinomas and adenocarcinomas?

<p>Squamous cell carcinomas disseminate late and locally, while adenocarcinomas disseminate early and widely (C)</p> Signup and view all the answers

Which factor most significantly worsens the effects of inhaled asbestos?

<p>Exposure to tobacco smoke (B)</p> Signup and view all the answers

What is the most prevalent chronic occupational disease in the world?

<p>Silicosis (B)</p> Signup and view all the answers

In cases of progressive massive fibrosis (PMF), which condition is often a result?

<p>Pulmonary hypertension and cor pulmonale (B)</p> Signup and view all the answers

What is a characteristic finding in asymptomatic workers diagnosed with silicosis on routine chest radiographs?

<p>Fine nodularity in the upper zones of the lung (B)</p> Signup and view all the answers

Which inhaled material is known to form complexed forms that have minimal pulmonary dysfunction?

<p>Simple coal dust (B)</p> Signup and view all the answers

What primary component does coal mine dust contain apart from carbon?

<p>Inorganic minerals and crystalline silica (A)</p> Signup and view all the answers

In terms of pathogenesis, what happens to most inhaled dust?

<p>It is entrapped in the mucus blanket and removed by ciliary movement (A)</p> Signup and view all the answers

Where do particles tend to get impacted in the lungs, leading to the accumulation of macrophages?

<p>Alveolar duct bifurcations (D)</p> Signup and view all the answers

Which type of emphysema is most commonly associated with cigarette smoking?

<p>Centriacinar (centrilobular) (B)</p> Signup and view all the answers

Which type of emphysema primarily involves the distal part of the acinus?

<p>Distal acinar (paraseptal) (A)</p> Signup and view all the answers

Which type of emphysema is associated with α1-antitrypsin deficiency?

<p>Panacinar (panlobular) (D)</p> Signup and view all the answers

Which type of emphysema often comes to attention in young adults with spontaneous pneumothorax?

<p>Distal acinar (paraseptal) (A)</p> Signup and view all the answers

Which type of emphysema is almost invariably associated with scarring?

<p>Irregular (D)</p> Signup and view all the answers

The first symptom usually noticed in emphysema patients is:

<p>Dyspnea (A)</p> Signup and view all the answers

In patients with chronic bronchitis, the initial complaints may include:

<p>Wheezing (B)</p> Signup and view all the answers

Chronic bronchitis is defined by the presence of a persistent productive cough for at least how long?

<p>3 consecutive months in at least 2 years (C)</p> Signup and view all the answers

What is a characteristic feature of the pathogenesis of early-stage disease described in the text?

<p>Hypersecretion of mucus (A)</p> Signup and view all the answers

Which environmental irritant is most notably linked to the disease described?

<p>Cigarette smoking (D)</p> Signup and view all the answers

What type of cells increase in the epithelial surfaces of smaller bronchi and bronchioles due to environmental irritants?

<p>Goblet cells (A)</p> Signup and view all the answers

Which inflammatory cells are involved in the reaction to environmental irritants?

<p>Macrophages, neutrophils, and lymphocytes (A)</p> Signup and view all the answers

What symptoms can persist indefinitely in some patients without ventilatory dysfunction?

<p>Cough and sputum production (D)</p> Signup and view all the answers

Which of the following is NOT a hallmark of asthma?

<p>Irreversible airway obstruction (C)</p> Signup and view all the answers

What major factors contribute to the development of asthma?

<p>Genetic predisposition to type I hypersensitivity, acute and chronic airway inflammation, bronchial hyperresponsiveness (B)</p> Signup and view all the answers

How is asthma most commonly classified in terms of its origin?

<p>Atopic and nonatopic (A)</p> Signup and view all the answers

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