Podcast
Questions and Answers
Ossification centers develop in the ______ connective tissue membrane.
Ossification centers develop in the ______ connective tissue membrane.
fibrous
Mesenchymal cells cluster and differentiate into ______, forming an ossification center.
Mesenchymal cells cluster and differentiate into ______, forming an ossification center.
osteoblasts
Osteoid is secreted and ______.
Osteoid is secreted and ______.
calcifies
Accumulating osteoid is laid down between embryonic blood vessels, forming a honeycomb of immature ______ bone.
Accumulating osteoid is laid down between embryonic blood vessels, forming a honeycomb of immature ______ bone.
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Compact bone replaces immature spongy bone, just deep to the ______.
Compact bone replaces immature spongy bone, just deep to the ______.
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Intramembranous ossification forms the cranial bones of the skull (frontal, parietal, occipital, and temporal bones) and the ______.
Intramembranous ossification forms the cranial bones of the skull (frontal, parietal, occipital, and temporal bones) and the ______.
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Endochondral ossification is more complex than __________ ossification
Endochondral ossification is more complex than __________ ossification
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Ossification begins when the underlying mesenchymal cells specialize into __________
Ossification begins when the underlying mesenchymal cells specialize into __________
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The perichondrium becomes __________ as osteoblasts secrete osteoid
The perichondrium becomes __________ as osteoblasts secrete osteoid
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Osteoblasts secrete osteoid against the hyaline cartilage diaphysis, encasing it in a collar of __________
Osteoblasts secrete osteoid against the hyaline cartilage diaphysis, encasing it in a collar of __________
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Endochondral ossification uses hyaline cartilage 'bones' formed earlier as models for bone __________
Endochondral ossification uses hyaline cartilage 'bones' formed earlier as models for bone __________
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Beginning late in the second month of development, endochondral ossification process begins using __________ cartilage
Beginning late in the second month of development, endochondral ossification process begins using __________ cartilage
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In endochondral ossification, a bone develops by replacing ______ cartilage.
In endochondral ossification, a bone develops by replacing ______ cartilage.
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In intramembranous ossification, a bone develops from a fibrous ______.
In intramembranous ossification, a bone develops from a fibrous ______.
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The beauty of using flexible structures (membranes and cartilages) to fashion the embryonic skeleton is that they can accommodate ______.
The beauty of using flexible structures (membranes and cartilages) to fashion the embryonic skeleton is that they can accommodate ______.
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If the early skeleton was composed of calcified bone tissue from the outset, growth would be much more ______.
If the early skeleton was composed of calcified bone tissue from the outset, growth would be much more ______.
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Bone tissue begins to develop at about this time and eventually replaces most of the existing fibrous or ______ structures.
Bone tissue begins to develop at about this time and eventually replaces most of the existing fibrous or ______ structures.
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Bones are capable of growing thicker throughout ______.
Bones are capable of growing thicker throughout ______.
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Study Notes
- Long bones in adults undergo endochondral ossification, where hyaline cartilage models are replaced by bone tissue.
- Osteoblasts in the periosteum secrete osteoid against the hyaline cartilage diaphysis, encasing it in a collar of bone during ossification.
- Ossification centers develop in a fibrous connective tissue membrane where mesenchymal cells cluster and differentiate into osteoblasts.
- Intramembranous ossification forms cranial bones and clavicles, while endochondral ossification replaces hyaline cartilage with bone tissue.
- The embryonic skeleton initially consists of fibrous connective tissue membranes and hyaline cartilage before bone tissue development begins.
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Description
Test your knowledge on the anatomy of long bones by drawing a cross-section with specific labels. Identify bone cells and their functions. Connect bone cell activity with cellular organelles for bone matrix digestion.
