Long Bone Cross Section Anatomy and Bone Cells Quiz

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18 Questions

Ossification centers develop in the ______ connective tissue membrane.

fibrous

Mesenchymal cells cluster and differentiate into ______, forming an ossification center.

osteoblasts

Osteoid is secreted and ______.

calcifies

Accumulating osteoid is laid down between embryonic blood vessels, forming a honeycomb of immature ______ bone.

spongy

Compact bone replaces immature spongy bone, just deep to the ______.

periosteum

Intramembranous ossification forms the cranial bones of the skull (frontal, parietal, occipital, and temporal bones) and the ______.

clavicles

Endochondral ossification is more complex than __________ ossification

intramembranous

Ossification begins when the underlying mesenchymal cells specialize into __________

osteoblasts

The perichondrium becomes __________ as osteoblasts secrete osteoid

periosteum

Osteoblasts secrete osteoid against the hyaline cartilage diaphysis, encasing it in a collar of __________

bone

Endochondral ossification uses hyaline cartilage 'bones' formed earlier as models for bone __________

construction

Beginning late in the second month of development, endochondral ossification process begins using __________ cartilage

hyaline

In endochondral ossification, a bone develops by replacing ______ cartilage.

hyaline

In intramembranous ossification, a bone develops from a fibrous ______.

membrane

The beauty of using flexible structures (membranes and cartilages) to fashion the embryonic skeleton is that they can accommodate ______.

mitosis

If the early skeleton was composed of calcified bone tissue from the outset, growth would be much more ______.

difficult

Bone tissue begins to develop at about this time and eventually replaces most of the existing fibrous or ______ structures.

cartilage

Bones are capable of growing thicker throughout ______.

life

Study Notes

  • Long bones in adults undergo endochondral ossification, where hyaline cartilage models are replaced by bone tissue.
  • Osteoblasts in the periosteum secrete osteoid against the hyaline cartilage diaphysis, encasing it in a collar of bone during ossification.
  • Ossification centers develop in a fibrous connective tissue membrane where mesenchymal cells cluster and differentiate into osteoblasts.
  • Intramembranous ossification forms cranial bones and clavicles, while endochondral ossification replaces hyaline cartilage with bone tissue.
  • The embryonic skeleton initially consists of fibrous connective tissue membranes and hyaline cartilage before bone tissue development begins.

Test your knowledge on the anatomy of long bones by drawing a cross-section with specific labels. Identify bone cells and their functions. Connect bone cell activity with cellular organelles for bone matrix digestion.

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