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Questions and Answers
Match the following surface anesthetics with their solubility properties:
Match the following surface anesthetics with their solubility properties:
Cocaine = Soluble Lignocaine = Soluble Benzocaine = Insoluble Oxethazaine = Insoluble
Match the following properties with Ester LAs or Amide LAs:
Match the following properties with Ester LAs or Amide LAs:
Short duration = Ester LAs Longer duration = Amide L As Less intense analgesia = Ester LAs More intense analgesia = Amide L As
Match the following hypersensitivity risk with the respective type of local anesthetic:
Match the following hypersensitivity risk with the respective type of local anesthetic:
High risk = Ester LAs Low risk = Amide L As Hydrolyzed by plasma = Ester LAs Metabolized in the liver = Amide L As
Match the following unwanted effects with their respective effects of local anesthetics:
Match the following unwanted effects with their respective effects of local anesthetics:
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Match the following types of local anesthesia with their description:
Match the following types of local anesthesia with their description:
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Match the following properties with ideal local anesthetics:
Match the following properties with ideal local anesthetics:
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Match the following local anesthetic classifications with their chemical class:
Match the following local anesthetic classifications with their chemical class:
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Match the following local anesthetics with their classification:
Match the following local anesthetics with their classification:
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Study Notes
Local Anesthetics Overview
- Local anesthetics (LAs) are drugs used to block pain in a specific area without affecting consciousness.
- Classified into two main types: Ester LAs and Amide LAs, each with distinct chemical properties.
Solubility Properties
- Ester LAs are generally more soluble in water and have a shorter duration of action.
- Amide LAs are less soluble but offer prolonged effects and stability.
Hypersensitivity Risk
- Ester LAs have a higher risk of hypersensitivity due to the presence of para-aminobenzoic acid (PABA).
- Amide LAs are less likely to cause allergic reactions, making them safer in this regard.
Unwanted Effects
- Common unwanted effects of local anesthetics include transient neurological symptoms, cardiovascular effects, and allergic reactions.
- Symptoms may range from mild (tingling) to severe (convulsions or cardiac arrest).
Types of Local Anesthesia
- Topical anesthesia involves applying the anesthetic directly to mucous membranes or skin.
- Regional anesthesia involves injecting anesthetic near a nerve to block sensation in a larger area.
Properties of Ideal Local Anesthetics
- Should be effective without causing significant side effects.
- Must have a rapid onset and sufficient duration of action to suit specific surgical needs.
Local Anesthetic Classifications
- Local anesthetics are classified based on their chemical structure:
- Esters: e.g., procaine, tetracaine
- Amides: e.g., lidocaine, bupivacaine
Local Anesthetics and Their Classifications
- Common Ester LAs include procaine, benzocaine, and chloroprocaine.
- Common Amide LAs include lidocaine, mepivacaine, and ropivacaine, widely used for various medical procedures.
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Description
Test your knowledge on local anesthetics with this quiz. Learn about the advantages, properties, classification, mechanism of action, rational uses, and differences between ester and amide local anesthetics. Understand the main unwanted effects and enhance your understanding of this important aspect of pharmacology.
