Local Anesthetics Quiz
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Questions and Answers

What happens when the concentration of local anesthetic (LA) reaches a significant level in the body?

  • It affects organs dependent on sodium channel conduction. (correct)
  • It causes immediate relief of pain.
  • It results in rapid metabolism of the drug.
  • It leads to a concentration in the muscle tissue.

    • Which factor does NOT influence the rate of absorption of local anesthetics into the systemic circulation?

  • Presence of soluble salts in the anesthetic.
  • Type of organ affected by sodium channels. (correct)
  • Vascularity of the injection site.
  • Amount of local anesthetic given.

    • What is a potential consequence of high binding capacity of local anesthetics like bupivacaine?

  • Faster onset of pain relief.
  • Decrease in metabolism speed.
  • Increased duration of action and risk of toxicity. (correct)
  • Diminished effectiveness due to dilution.

    • What is the most likely cause of life-threatening symptoms after plasma saturation with local anesthetics?

    <p>Increase in the level of free drug in circulation.</p> Signup and view all the answers

    How does enzyme dysfunction in plasma affect local anesthetic metabolism?

    <p>It can reduce the metabolism of local anesthetics.</p> Signup and view all the answers

    Which component of blood primarily carries local anesthetics in the plasma?

    <p>Water and other solutes.</p> Signup and view all the answers

    Which tissue is most likely to be affected by systemic local anesthetic toxicity due to high blood perfusion?

    <p>Cardiac muscle.</p> Signup and view all the answers

    What percentage of plasma is composed of water?

    <p>91%</p> Signup and view all the answers

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