Liver Pathology and Anatomy Review
27 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which enzyme is responsible for converting pre-genomic RNA to DNA during HBV replication?

  • DNA polymerase
  • RNA ligase
  • RNA polymerase
  • Reverse transcriptase (correct)

Which type of hepatitis virus is known for having the most aggressive course?

  • HAV
  • HDV
  • HBV
  • HCV (correct)

What is the main route of transmission for HBV?

  • Sexual contact (correct)
  • Feco-oral
  • Respiratory droplets
  • Skin contact

During the Icteric Phase of viral hepatitis, what causes the yellow discoloration of the skin and sclera?

<p>Increase in bile pigment bilirubin (A)</p> Signup and view all the answers

Which hepatitis virus requires the presence of HBV to infect a host?

<p>HDV (D)</p> Signup and view all the answers

Which phase of viral hepatitis infection is characterized by flu-like symptoms and affects the brain and gastrointestinal system?

<p>Prodromal Phase (A)</p> Signup and view all the answers

What induces cytotoxicity in hepatocytes during viral hepatitis infection?

<p>Perforin and granzymes released from cytotoxic T cells (C)</p> Signup and view all the answers

Which hepatitis virus is shed in stool and is associated with acute and chronic infections?

<p>HEV (D)</p> Signup and view all the answers

What is the primary mode of transmission for HCV?

<p>Blood exposure (B)</p> Signup and view all the answers

In the replication process of HBV with dsDNA, where does the pdsDNA get released into?

<p>Nucleus (D)</p> Signup and view all the answers

Which hepatitis virus has a circular ssRNA genome and can only infect in the presence of HBV?

<p>HDV (A)</p> Signup and view all the answers

Which enzyme finishes forming pdsDNA in the nucleus during HBV replication?

<p>DNA polymerase (A)</p> Signup and view all the answers

What causes the formation of pores in hepatocytes during viral hepatitis infection?

<p>Perforin released from cytotoxic T cells (B)</p> Signup and view all the answers

Which type of hepatitis virus has the shortest average duration for acute infection?

<p>HAV (D)</p> Signup and view all the answers

During viral hepatitis infection, which enzyme leaks into circulation causing hepatomegaly and pain in the upper right quadrant?

<p>ALT, AST, ALP, GGT (B)</p> Signup and view all the answers

How is HEV primarily transmitted?

<p>Feco-oral route (D)</p> Signup and view all the answers

What leads to the production of pre-genomic RNA during HBV replication?

<p>RNA polymerase transcription of dsDNA to RNA (D)</p> Signup and view all the answers

What is the distinctive feature of HBV's genome compared to other hepatitis viruses?

<p>Partial dsDNA genome with a lipid bilayer envelope (A)</p> Signup and view all the answers

Which phase of viral hepatitis infection marks the recovery phase with diminished flu-like symptoms and resolving jaundice?

<p>Convalescent Phase (A)</p> Signup and view all the answers

What is the main difference between HBV and HDV in terms of infectivity?

<p>HBV can infect independently, while HDV needs HBV for co-infection. (C)</p> Signup and view all the answers

What is the functional unit of the liver?

<p>Hepatocytes (D)</p> Signup and view all the answers

What is the role of Kupffer cells in the liver?

<p>Remove debris and bacteria (D)</p> Signup and view all the answers

Which part of the liver receives oxygen from the hepatic artery in Zone 1 of the hepatic acinus?

<p>Encircles the portal triad (B)</p> Signup and view all the answers

What is the main cause of most cases of acute liver diseases?

<p>Viral hepatitis infection (D)</p> Signup and view all the answers

Which part of the liver lobule contains the highest oxygenation?

<p>Zone 1 of hepatic acinus (C)</p> Signup and view all the answers

What is the primary function of sinusoids in the liver?

<p>Supply oxygenated blood to hepatocytes (A)</p> Signup and view all the answers

Which type of hepatitis infection lasts for less than 6 months?

<p>HAV (B)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser