Lithium Carbonate Flashcards

Study Notes

Lithium Carbonate Overview

Generic name for Lithium Carbonate is Eskalith.
Classified pharmacologically as an antipsychotic and mood stabilizer.
Therapeutically classified as an antipsychotic, antimanic, and antidepressant.

FDA Classification

Lithium is categorized as Pregnancy Category D, indicating potential risks.

Mechanism of Action

Lithium decreases the overactivity of receptors linked to manic states.
It accelerates catecholamine destruction, inhibits neurotransmitter release, and reduces sensitivity of postsynaptic receptors.

Metabolism and Excretion

Lithium is not metabolized by the body and is eliminated through urine by the kidneys.

Dosage and Administration

Loading dose: 600 mg taken three times daily or 900 mg of sustained release taken twice daily.
Maintenance dose: 800 mg taken three to four times daily.

Contraindications and Interactions

Possible side effects include dizziness, headache, fatigue, slurred speech, as well as severe reactions like coma and seizures.
Other serious conditions include ventricular arrhythmias, syncope, Brugada syndrome, goiter, and diabetes insipidus.

Pre-Administration Assessment

Monitor patient response to medication, noting that it takes 1-2 weeks to observe effects.
Regular lithium level testing is necessary.
Watch for signs of lithium toxicity: vomiting, diarrhea, coordination issues, drowsiness, muscular weakness, and slurred speech.
Avoid abrupt cessation of the medication.

Nursing Administration Techniques

Lithium should be administered with meals.
Protect lithium from light and moisture to maintain stability.

Patient Education and Evaluation

Patients should be aware of increased urine output and persistent thirst as common effects.
Advise to contact a provider if diarrhea or fever occurs.
Encourage adequate liquid intake and contraception use.
Caution against performing hazardous activities until side effects are understood.

Description

Test your knowledge about Lithium Carbonate with these informative flashcards. Explore its generic name, pharmacologic and therapeutic classifications, FDA category, and mechanism of action. Perfect for pharmacy students or healthcare professionals looking to refresh their memory.