Listeria Cell-to-Cell Spread Mechanism
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Questions and Answers

Which statement best describes the characteristic of obligate intracellular bacteria mentioned in the text?

  • They can survive outside host cells in artificial media.
  • They primarily replicate in the host lysosome to ensure survival.
  • They lack many biosynthetic pathways and depend on the host cell for ATP and other molecules. (correct)
  • They are able to carry out energy metabolism independently.

    • In the context of obligate intracellular bacteria, which best describes the role of Coxiella burnetii?

  • It is an obligate intracellular bacterium causing acute and chronic infections. (correct)
  • It is an organism that can be easily cultured on agar plates and broths.
  • It is a bacterium that primarily spreads by actin polymerization.
  • It is an extracellular bacterium that can survive independently of a host cell.

    • Which process is involved in the chlamydial growth cycle according to the text?

  • Release of elementary bodies (EB) from lysosomes to infect surrounding epithelial cells.
  • Promotion of cell-to-cell spreading of chlamydia in the host.
  • Binary fission of reticulate bodies (RB) inside host cells. (correct)
  • Formation of actin polymerization to propel bacteria unidirectionally.

    • What is a characteristic of obligate intracellular pathogens?

    <p>They are shielded from humoral antibodies</p> Signup and view all the answers

    How do obligate intracellular pathogens achieve invasion?

    <p>By entering host cells and reproducing</p> Signup and view all the answers

    What differentiates obligate intracellular pathogens from facultative intracellular pathogens?

    <p>Can only reproduce inside host cells</p> Signup and view all the answers

    What is the compartment where C. burnetii replicates inside alveolar macrophages?

    <p>Phagolysosome</p> Signup and view all the answers

    Which of the following is NOT an obligate intracellular bacterium from the text?

    <p>Bacillus anthracis</p> Signup and view all the answers

    How does C. burnetii escape immune detection as described in the text?

    <p>By replicating within a compartment similar to a phagolysosome</p> Signup and view all the answers

    What is the main method through which host cells defend against intracellular pathogens?

    <p>Recognition of pathogens through PAMPs</p> Signup and view all the answers

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