Podcast
Questions and Answers
What is the primary mode of transmission of Cholera?
What is the primary mode of transmission of Cholera?
- Direct contact transmission
- Vector-borne transmission
- Respiratory route
- Faecal-oral route (correct)
What is the primary target of the B subunits of the Cholera toxin?
What is the primary target of the B subunits of the Cholera toxin?
- Cyclic AMP
- GM1 ganglioside receptor (correct)
- Adenylate cyclase
- G proteins
What is the enzyme stimulated by the G protein in the Cholera toxin mechanism?
What is the enzyme stimulated by the G protein in the Cholera toxin mechanism?
- Adenylate kinase
- Guanosine kinase
- Cyclic AMP synthase
- Adenylate cyclase (correct)
What is the consequence of good sanitation in the context of Cholera transmission?
What is the consequence of good sanitation in the context of Cholera transmission?
What is the historical correlation between Cholera prevalence and genetics in Northern Europe?
What is the historical correlation between Cholera prevalence and genetics in Northern Europe?
What was the trigger for the recent outbreak of Cholera in Haiti?
What was the trigger for the recent outbreak of Cholera in Haiti?
What is the mechanism of action of the A1 subunit of the Shiga toxin?
What is the mechanism of action of the A1 subunit of the Shiga toxin?
What is the site of entry for L. monocytogenes in the host?
What is the site of entry for L. monocytogenes in the host?
What is the primary target of the Shiga toxin in the body?
What is the primary target of the Shiga toxin in the body?
What is the name of the syndrome that may occur in 3% of individuals infected with Shigella flexneri?
What is the name of the syndrome that may occur in 3% of individuals infected with Shigella flexneri?
What protein is involved in the adherence of L. monocytogenes to host cells?
What protein is involved in the adherence of L. monocytogenes to host cells?
What is the name of the toxin produced by Vibrio cholerae?
What is the name of the toxin produced by Vibrio cholerae?
Which signaling pathway is activated by the InlA-invasion pathway?
Which signaling pathway is activated by the InlA-invasion pathway?
What is the primary function of Internalin B in L. monocytogenes pathogenesis?
What is the primary function of Internalin B in L. monocytogenes pathogenesis?
What is the function of the B subunits of the Shiga toxin?
What is the function of the B subunits of the Shiga toxin?
Why is the mouse model considered poor for studying L. monocytogenes?
Why is the mouse model considered poor for studying L. monocytogenes?
What is the name of the syndrome that can occur after S. dysenteriae type 1 infection?
What is the name of the syndrome that can occur after S. dysenteriae type 1 infection?
Which animal model is considered the best for studying L. monocytogenes?
Which animal model is considered the best for studying L. monocytogenes?
What was the approximate number of people killed in the 2010 earthquake in Haiti?
What was the approximate number of people killed in the 2010 earthquake in Haiti?
What was the strain of cholera found in Haiti during the 2010 epidemic?
What was the strain of cholera found in Haiti during the 2010 epidemic?
Where did the strain of cholera found in Haiti likely originate from?
Where did the strain of cholera found in Haiti likely originate from?
What was the estimated number of cholera cases per year worldwide according to the WHO?
What was the estimated number of cholera cases per year worldwide according to the WHO?
How long had it been since cholera was last reported in Haiti before the 2010 epidemic?
How long had it been since cholera was last reported in Haiti before the 2010 epidemic?
What is the primary function of the type III secretion system (T3SS) in pathogenic bacteria?
What is the primary function of the type III secretion system (T3SS) in pathogenic bacteria?
How does Shigella flexneri gain entrance to the host cell?
How does Shigella flexneri gain entrance to the host cell?
What is the primary mechanism of movement for Shigella?
What is the primary mechanism of movement for Shigella?
What is the name of the toxin family produced by Shigella dysenteriae and some E. coli?
What is the name of the toxin family produced by Shigella dysenteriae and some E. coli?
What is the function of the needle-like structures on the surface of Shigella?
What is the function of the needle-like structures on the surface of Shigella?
What is the purpose of the plaque assay in studying Shigella?
What is the purpose of the plaque assay in studying Shigella?
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