14 Questions
Which lipoprotein is produced by the liver to send triglycerides to cells for energy during fasting?
VLDL
What is the main function of HDL in the context of lipoprotein metabolism?
Removes excess cholesterol from tissues
Which lipoprotein is considered the 'bad guy' due to its cholesterol-rich content and association with atherosclerosis?
LDL
What is the main form of dietary and endogenous fat in the body?
Triglycerides
How are chylomicrons formed?
Bile salts break down dietary fats in intestines
What is the daily synthesis rate of cholesterol in humans?
$700$ mg
How do chylomicrons primarily deliver fats to the body?
By traveling through lymph to reach various tissues
What is the role of lipoprotein lipase in the body's fat metabolism?
Breaking down triglycerides in chylomicrons into glycerol and free fatty acids
How are remnants of chylomicrons cleared from the body?
By being taken up by remnant receptors in the liver
What happens to VLDL remnants that are not removed by the liver?
They circulate and become plaque
What is the role of LDL receptors in the body's cholesterol regulation?
They facilitate the uptake of LDL by all cells
How does ApoA1 protein contribute to cholesterol removal by HDLs?
It pulls out cholesterol from cell macrophages to form HDLs
What characterizes lipoprotein (a) or Lp(a) as an inherited risk factor for cardiovascular disease?
It has genetic determinants and poses a risk for heart disease and stroke
What distinguishes primary dyslipidemia from secondary dyslipidemia?
Primary dyslipidemia is caused by genetic factors while secondary dyslipidemia is due to diet and other factors
Explore the functions of cholesterol and triglycerides in lipoprotein metabolism. Learn about how cholesterol is a component of cell membranes, steroid hormones, and bile salts, while triglycerides serve as the main form of dietary and endogenous fat. Understand the synthesis and metabolism of these important lipids.
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