Lipid Disorders: Lipoprotein Metabolism and Cholesterol

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Questions and Answers

What is the function of apolipoproteins in lipoprotein metabolism?

  • To facilitate the transport of triglycerides and cholesterol (correct)
  • To promote the aggregation of platelets
  • To increase the production of thromboxane
  • To decrease the risk of cardiovascular disease

What is the Omega (ω) numbering system used for?

  • To identify the family of omega-3 fatty acids (correct)
  • To calculate the molecular weight of a fatty acid
  • To classify fatty acids based on their chain length
  • To determine the number of double bonds in a fatty acid

What is the name of the fatty acid with the formula C16:0?

  • Palmitate (correct)
  • Linoleic acid
  • Arachidonic acid
  • Linolenic acid

What is the effect of a diet high in omega-3 fatty acids on serum triglycerides?

<p>It decreases serum triglycerides (D)</p> Signup and view all the answers

What is the order of lipoproteins in increasing density?

<p>Chylomicrons &lt; VLDL &lt; IDL &lt; LDL &lt; HDL (B)</p> Signup and view all the answers

What is the main function of lipoproteins?

<p>To transport triglycerides and cholesterol in the blood (A)</p> Signup and view all the answers

What is the name of the fatty acid with the formula C20:4 (5,8,11,14)?

<p>Arachidonic acid (B)</p> Signup and view all the answers

What is the purpose of omega-3 fatty acids in platelet membranes?

<p>To decrease the production of thromboxane (B)</p> Signup and view all the answers

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Study Notes

Lipoproteins and Fatty Acids

  • Fatty acids are long-chain carboxylic acids, with the carboxyl carbon as number 1 and the α carbon as number 2.
  • Fatty acid nomenclature includes the number of carbons and double bonds (e.g., C16:0 for palmitate).
  • Saturated fatty acids have no double bonds.

Omega Fatty Acids

  • The omega (ω) numbering system is used to designate fatty acids (e.g., linoleic C18:2 (9,12) or 18Δ9,12 ω-6 family).
  • Omega-3 fatty acids are correlated with a decreased risk of cardiovascular disease.
  • Omega-3 fatty acids can replace arachidonic acid in platelet membranes, reducing thromboxane production and platelet aggregation.

Lipoprotein Metabolism

  • Lipoproteins transport triglycerides and cholesterol in the blood.
  • Lipoproteins are named according to their density, increasing with protein percentage:
    • Chylomicrons (least dense)
    • VLDL (very low-density lipoproteins)
    • IDL (intermediate-density lipoproteins)
    • LDL (low-density lipoproteins)
    • HDL (high-density lipoproteins)

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