Lipids: Fixed Oils, Fats, and Waxes
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Questions and Answers

What distinguishes fats from fixed oils in terms of physical state at normal temperatures?

  • Fats have a higher molecular weight alcohol.
  • Fats cannot be used nutritionally.
  • Fats are semisolid or solid, while fixed oils are liquid. (correct)
  • Fats are of animal origin only.
  • Which of the following is a characteristic physical property of fixed oils and fats?

  • They are denser than water.
  • They volatilize on exposure to air.
  • They leave a permanent translucent stain on paper. (correct)
  • They are soluble in water.
  • What type of lipid contains sulfur in its structure?

  • Aminolipids
  • Glucolipids
  • Sulpholipids (correct)
  • Phospholipids
  • How are animal fats typically separated from other tissues?

    <p>By rendering with steam, possibly under pressure. (A)</p> Signup and view all the answers

    Which statement about glycerides of fatty acids is true?

    <p>Glycerides consist of fatty acids linked with glycerol. (D)</p> Signup and view all the answers

    What distinguishes 'cold-pressed oil' from 'hot-pressed oil'?

    <p>Cold-pressed oils are extracted at low temperatures. (D)</p> Signup and view all the answers

    What is the primary function of lipids such as fixed oils and fats?

    <p>Food (energy) storage. (D)</p> Signup and view all the answers

    Which type of lipid is characterized by containing carbohydrates in its structure?

    <p>Glucolipids (D)</p> Signup and view all the answers

    What is the primary source of carbon units in the biosynthesis of fatty acids?

    <p>Malonyl-CoA (D)</p> Signup and view all the answers

    What is indicated by the acid value of fixed oils?

    <p>The amount of free fatty acid in the oil (D)</p> Signup and view all the answers

    What effect does hydrogenation have on the chemical properties of fats?

    <p>Decreases rancidity (B)</p> Signup and view all the answers

    Which type of rancidity is primarily caused by the action of the enzyme lipase?

    <p>Hydrolytic rancidity (A)</p> Signup and view all the answers

    Which type of oil is characterized by a high content of oleic acid glycerides and does not dry upon exposure to air?

    <p>Nondrying oils (D)</p> Signup and view all the answers

    Which test can be used to determine the degree of unsaturation in fixed oils?

    <p>Iodine number (A)</p> Signup and view all the answers

    What effect does hydrogenation have on fixed oils?

    <p>Slows down the development of rancidity (B)</p> Signup and view all the answers

    During the polymerization of oils, what effect does prolonged heating in an inert atmosphere have?

    <p>Produces a more saturated oil or cyclic structure (A)</p> Signup and view all the answers

    Which of the following oils is typically involved in the hydrogenation process to produce solid cooking fats?

    <p>Cotton oil (B)</p> Signup and view all the answers

    What is a significant result of oxidative rancidity in fixed oils?

    <p>Formation of cyclic polymers (C)</p> Signup and view all the answers

    What is the process called that allows unsaturated fixed oils to add hydrogen to their double bonds?

    <p>Hydrogenation (A)</p> Signup and view all the answers

    Which physical constant is NOT typically used to identify or evaluate the quality of fixed oils?

    <p>Boiling point (C)</p> Signup and view all the answers

    Which of the following is an emollient property of fixed oils utilized in pharmaceutical formulations?

    <p>Creating emulsions (C)</p> Signup and view all the answers

    What is the result of the reaction between malonyl-CoA and butyryl-CoA in the biosynthesis of fatty acids?

    <p>Generation of a 7-carbon intermediate (B)</p> Signup and view all the answers

    What must be controlled to prevent hydrolytic rancidity effectively?

    <p>Moisture levels (D)</p> Signup and view all the answers

    Why is fat hardening a significant process in the fat industry?

    <p>It makes fats less susceptible to rancidification (B)</p> Signup and view all the answers

    Which of the following best describes castor oil?

    <p>A laxative with a usual dose of 15 to 60 ml (A)</p> Signup and view all the answers

    What is a primary use of linseed oil?

    <p>As a demulcent and laxative (A)</p> Signup and view all the answers

    What characterizes cottonseed oil in pharmaceutical applications?

    <p>Serves as a solvent for injections (B)</p> Signup and view all the answers

    Which oil is referred to as cacao butter?

    <p>Theobroma oil (C)</p> Signup and view all the answers

    What is a significant property of sesame oil?

    <p>It functions as a solvent for intramuscular injections (D)</p> Signup and view all the answers

    Lard is mainly recognized for which of the following uses?

    <p>As a base for skin creams (C)</p> Signup and view all the answers

    Which statement about lanolin is true?

    <p>It is a primary ingredient in many skin creams and cosmetics (C)</p> Signup and view all the answers

    Higly molecular weight esters are commonly known as?

    <p>Waxes (A)</p> Signup and view all the answers

    What is a primary therapeutic property of castor oil?

    <p>Stimulant cathartic (D)</p> Signup and view all the answers

    What primarily distinguishes fixed oils from fats based on their physical properties?

    <p>Fixed oils have a lower melting point than fats. (A)</p> Signup and view all the answers

    In which of the following applications is olive oil NOT typically used?

    <p>Antiseptic ointments (A)</p> Signup and view all the answers

    Which type of lipids are classified as having fatty acids combined with glycerol and containing other functional groups?

    <p>Compound lipids (A)</p> Signup and view all the answers

    Which of the following is a common use for cottonseed oil?

    <p>Solvent for injections (D)</p> Signup and view all the answers

    What is the primary method for obtaining fixed oils and fats of vegetable origin?

    <p>Compression (A)</p> Signup and view all the answers

    Which property of sesame oil makes it suitable for pharmaceuticals?

    <p>Nutritive and laxative (B)</p> Signup and view all the answers

    Which property describes fixed oils and fats in relation to water?

    <p>They are insoluble in water. (A)</p> Signup and view all the answers

    What is a primary characteristic of lanolin?

    <p>Fat-like substance from sheep's wool (C)</p> Signup and view all the answers

    What type of alcohol is predominantly found in the structure of fixed oils and fats?

    <p>Glycerol (D)</p> Signup and view all the answers

    Which type of oil is primarily used in the manufacture of ointments due to its emollient properties?

    <p>Lard (B)</p> Signup and view all the answers

    What distinguishes cold-pressed oils from those that are hot-pressed?

    <p>Cold-pressed oils yield higher quality. (D)</p> Signup and view all the answers

    What is the main use of Theobroma oil?

    <p>Suppository base (C)</p> Signup and view all the answers

    Which type of lipid contains nitrogen in its structure?

    <p>Aminolipids (D)</p> Signup and view all the answers

    Which oil is often referred to as sweet oil and is also a nutrient?

    <p>Olive oil (C)</p> Signup and view all the answers

    What is the main characteristic of glycerides made from saturated fatty acids?

    <p>They are typically solid at room temperature. (D)</p> Signup and view all the answers

    What does the saponification value indicate in fixed oils and fats?

    <p>The number of mg of KOH needed to saponify 1 gm of fat (C)</p> Signup and view all the answers

    Which type of rancidity results from the action of the enzyme lipase?

    <p>Hydrolytic rancidity (C)</p> Signup and view all the answers

    What does the iodine number in fixed oils indicate?

    <p>The degree of unsaturation (D)</p> Signup and view all the answers

    Which of the following is a strategy to prevent oxidative rancidity in fixed oils?

    <p>Using antioxidants (D)</p> Signup and view all the answers

    Which of the following tests evaluates the presence of free fatty acids in fixed oils?

    <p>Acid value test (B)</p> Signup and view all the answers

    Rancidity in fixed oils is primarily due to the formation of which harmful compounds?

    <p>Aldehydes and free fatty acids (C)</p> Signup and view all the answers

    To what does the term 'hydrogenation' refer in the context of fixed oils?

    <p>The conversion of unsaturated fats to saturated fats (A)</p> Signup and view all the answers

    Which of the following factors can influence the rancidity of fixed oils during storage?

    <p>Temperature and light exposure (C)</p> Signup and view all the answers

    What compound is formed when acetate reacts with CoA in the biosynthesis of lipids?

    <p>Malonyl-CoA (B)</p> Signup and view all the answers

    Which type of oils are classified as nondrying oils?

    <p>Oils that contain large quantities of oleic acid glycerides. (C)</p> Signup and view all the answers

    What is the primary benefit of fat hardening in the fat industry?

    <p>To increase resistance to rancidification. (C)</p> Signup and view all the answers

    What happens to the unsaturated components of oils during fat polymerization?

    <p>They react with each other to form more saturated oils. (D)</p> Signup and view all the answers

    How does the malonyl portion of malonyl-CoA contribute to fatty acid biosynthesis?

    <p>It provides the 3-carbon units that form fatty acids. (C)</p> Signup and view all the answers

    Why do hydrogenated fats become rancid less readily than non-hydrogenated oils?

    <p>They contain fewer double bonds. (A)</p> Signup and view all the answers

    What type of reaction leads to the formation of a cyclic structure during fat polymerization?

    <p>Heating unsaturated oils in an inert atmosphere. (A)</p> Signup and view all the answers

    Flashcards

    Lipids

    Esters of fatty acids and alcohols, including fixed oils, fats, and waxes.

    Fixed Oils/Fats

    Glycerides (esters of glycerol alcohol and fatty acids) that are liquid or semi-solid at room temperature.

    Waxes

    Glycerides with higher molecular weight alcohols (e.g., cetyl alcohol) instead of glycerol, typically solid at room temperature.

    Glycerides

    Esters of glycerol alcohol and fatty acids.

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    Saturated Fatty Acids

    Fatty acids with no double bonds between carbon atoms, generally solid at room temperature.

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    Unsaturated Fatty Acids

    Fatty acids with one or more double bonds between carbon atoms, usually liquid at room temperature.

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    Cold-Pressed Oil

    Fixed oil obtained by compression at low temperatures.

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    Rendering

    Process for separating animal fats from tissues by melting with steam, with or without pressure.

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    Semidrying Oils

    Fixed oils containing both oleic and linoleic acids, resulting in a semi-solid consistency at room temperature.

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    Drying Oils

    Fixed oils rich in linoleic acid, known for their ability to solidify upon exposure to air, forming a hard, protective layer.

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    Acid Value

    A measure of the amount of free fatty acids present in a fixed oil or fat, expressed as milligrams of potassium hydroxide (KOH) needed to neutralize 1 gram of the substance.

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    Saponification Value

    Indicates the amount of KOH needed to completely saponify (convert) 1 gram of fat or oil into soap.

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    Iodine Number

    A measure of the degree of unsaturation in a fixed oil or fat, indicating the amount of iodine absorbed per 100 grams of the substance.

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    Hydrolytic Rancidity

    Deterioration of fats and oils caused by the breakdown of triglycerides into free fatty acids, often initiated by the enzyme lipase.

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    Oxidative Rancidity

    Spoilage of fats and oils due to reactions with oxygen, leading to the formation of unpleasant-smelling aldehydes and ketones.

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    Antioxidant Agents

    Chemicals added to fixed oils and fats to prevent or slow down oxidative rancidity.

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    Where are vegetable oils found?

    Vegetable oils are commonly found in seeds of plants, but they can also occur in other parts of the plant. Seeds are known to contain larger quantities of oil compared to other parts.

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    What is malonyl-CoA's role in lipid biosynthesis?

    Malonyl-CoA, a 3-carbon compound, serves as the source of 2-carbon units that are added repeatedly to build the fatty acid chain during biosynthesis.

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    What is fat hardening?

    Fat hardening is a process that involves adding hydrogen to the double bonds in unsaturated oils, converting them into more saturated and solid fats.

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    What happens during fat polymerization?

    Heating unsaturated oils in an inert atmosphere promotes reactions between their double bonds, making them more saturated and modifying their structure. This leads to a more stable oil with less tendency for rancidity.

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    What are the benefits of hydrogenation?

    Hydrogenation not only changes the physical properties of fats (converting liquids into solids) but also improves their chemical stability, reducing their likelihood of becoming rancid.

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    What are drying oils?

    Drying oils readily absorb oxygen from the air, leading to oxidation of their double bonds, which then polymerize to form hard films. Examples include linseed oil, used in paints.

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    What are nondrying oils?

    Nondrying oils contain high amounts of glycerides of oleic acid. They may thicken slightly when exposed to air but don't dry completely. An example is olive oil.

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    What is the key factor determining the classification of a fixed oil?

    The ability of a fixed oil to absorb oxygen from the air, leading to oxidation and polymerization, classifies it as a drying, semidrying, or nondrying oil.

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    What is Castor Oil?

    Castor oil is extracted from the castor bean, a seed of the Ricinus communis plant. It contains about 45-55% of fixed oil and is used as a stimulant cathartic in medicine. It is also utilized in the manufacture of soaps.

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    What's the use of Linseed Oil?

    Linseed oil, extracted from dried flaxseeds, acts as a demulcent and laxative. It is also used for medicinal purposes.

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    What is Olive Oil used for?

    Olive oil, derived from olives, is a versatile substance used in various applications. It is widely used as a salad oil due to its nutritional value. It is also employed in soap making, plasters, and as a demulcent, emollient, and laxative.

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    How is Cottonseed Oil utilized?

    Cottonseed oil is obtained from cottonseeds and serves as a solvent for injections in the pharmaceutical industry. It is also extensively used in soap manufacturing.

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    What are the applications of Sesame Oil?

    Sesame oil, extracted from sesame seeds, is used as a solvent for injections, primarily intramuscular. It also exhibits nutritive, laxative, demulcent, and emollient properties.

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    What is Theobroma Oil known for?

    Theobroma oil, commonly known as cocoa butter, is derived from roasted cacao seeds. It is used in pharmaceuticals as a suppository base.

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    How is Lard used?

    Lard is purified internal fat from animals, primarily the abdomen. It has emollient properties and serves as a base for ointments.

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    What's the application of Lanolin?

    Lanolin, a purified substance from sheep wool, is utilized as an ingredient in various skincare creams and cosmetics. It has properties that make it suitable for skin products.

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    What are lipids?

    Lipids are esters of long-chain fatty acids and alcohols. They include fixed oils, fats, and waxes.

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    What's the difference between fixed oils and waxes?

    Fixed oils and fats are glycerides (esters of glycerol with fatty acids). Waxes use a higher molecular weight alcohol instead of glycerol.

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    How are vegetable oils obtained?

    Vegetable oils are extracted by compression. Cold compression produces 'virgin oil', while hot compression creates 'hot-pressed oil'.

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    What are phospholipids?

    Phospholipids are compound lipids that contain fatty acids, glycerol, and phosphoric acid.

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    Physical properties of fixed oils

    Fixed oils are lighter than water, insoluble in water, greasy, leave a translucent stain on paper, and don't evaporate easily.

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    How are animal fats obtained?

    Animal fats are extracted by rendering, which involves melting them with steam.

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    What determines if a glyceride is a fixed oil or fat?

    Glycerides of unsaturated fatty acids are liquid (oils), while glycerides of saturated fatty acids are solid (fats).

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    What makes castor oil unique?

    Castor oil is unusual because it dissolves in alcohol, unlike most other fixed oils.

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    What is the role of malonyl-CoA in lipid biosynthesis?

    Malonyl-CoA acts as a building block for fatty acids. Each molecule of malonyl-CoA contributes two carbon atoms to the growing fatty acid chain during biosynthesis.

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    What is the basis for classifying fixed oils?

    Fixed oils are categorized based on their ability to absorb oxygen from the air. This determines whether they are drying, semidrying, or nondrying oils.

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    What are semidrying oils?

    Semidrying oils contain both oleic and linoleic fatty acids, giving them a semi-solid consistency at room temperature.

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    What is the key characteristic of drying oils?

    Drying oils are rich in linoleic acid and solidify upon exposure to air, forming a hard protective layer.

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    What does 'acid value' tell us?

    Acid value measures the amount of free fatty acids in an oil, indicating its freshness and potential for rancidity.

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    What is the purpose of saponification value?

    Saponification value tells us the amount of KOH needed to turn 1 gram of oil into soap. It reflects the oil's fatty acid composition.

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    How does iodine number reflect an oil's properties?

    Iodine number measures the degree of unsaturation in an oil - higher iodine number means more double bonds.

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    What is hydrolytic rancidity?

    Hydrolytic rancidity is the breakdown of fats into free fatty acids, often caused by the enzyme lipase.

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    What causes oxidative rancidity?

    Oxidative rancidity occurs when fats react with oxygen, producing unpleasant-smelling aldehydes and ketones.

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    Why are antioxidants used?

    Antioxidants are added to oils to prevent or slow down oxidative rancidity, preserving their freshness and taste.

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    Castor Oil Source

    Castor oil comes from the seeds of the Ricinus communis plant.

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    Castor Oil Medical Use

    Castor oil is used as a stimulant laxative, meaning it helps to move things along in the digestive system.

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    Linseed Oil Source

    Linseed oil is extracted from the dried seeds of the Linum usitatissimum plant, also known as flaxseed.

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    Olive Oil Source

    Olive oil is obtained from the fruit of the Olea europaea plant, which produces olives.

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    Cottonseed Oil Source

    Cottonseed oil is extracted from the seeds of the Gossypium hirsutum plant, which produces cotton.

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    Sesame Oil Source

    Sesame oil is extracted from the seeds of the Sesamum indicum plant, also known as sesame seeds.

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    Theobroma Oil Alternate Name

    Theobroma oil is more commonly known as cocoa butter.

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    Lard Source

    Lard is a purified fat extracted from the internal fat of animals, often from the abdomen.

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    Study Notes

    Lipids (Fixed Oils, Fats, and Waxes)

    • Lipids are esters of long-chain fatty acids and alcohols.
    • The main difference between fixed oils and fats, and waxes is the type of alcohol.
    • In fixed oils and fats, glycerol alcohol (C3H8O3) combines with fatty acids (forming glycerides).
    • In waxes, the alcohol has a higher molecular weight, such as cetyl alcohol (C16H34O).
    • Fats and waxes can be from plants (like olive oil, peanut oil) or animals (like lard).
    • Their primary function is energy storage.
    • Fixed oils and fats are important in pharmaceuticals, industry, and nutrition.

    Classification of Lipids

    • Simple lipids: Esters of fatty acids with alcohol (e.g., fixed oils, fats, waxes).
    • Compound lipids: Esters of fatty acids with alcohol containing another group (e.g., phospholipids).

    Examples of Compound Lipids

    • 1- Phospholipids: Compounds of fatty acids with glycerol and phosphoric acid.
    • 2- Glucolipids: Compounds of fatty acids with glycerol and carbohydrates.
    • 3- Sulpholipids: Contain sulfur.
    • 4- Aminolipids: Contain nitrogen.

    Fixed Oils and Fats

    • Fixed oils and fats differ only in their melting point.
    • Liquids at normal temperatures are fixed oils.
    • Semisolid or solid at ordinary temperatures are fats.
    • Vegetable fixed oils and fats are obtained by compression.
    • If the compression is carried out in the cold, the oil is known as a "virgin oil" or "cold-pressed oil".
    • If the compression is carried out in heat, the oil is known as a "hot-pressed oil."
    • Animal fats are separated from other tissues by rendering with steam, with or without pressure.
    • The heat melts the fat, which rises to the top and can be separated by decantation.

    Chemical Properties

    • Chemically, fixed oils and fats are glycerides of fatty acids.
    • Glycerides of unsaturated fatty acids are liquid.
    • Glycerides of saturated fatty acids with sufficient chain length are solid.

    Physical Properties

    • Fixed oils and fats are lighter than water and insoluble in water.
    • They feel greasy.
    • They leave a permanent translucent stain on paper.
    • They don't volatilize when exposed to air.
    • They are freely soluble in ether, chloroform, and light petroleum but usually insoluble in alcohol (castor oil is an exception)

    Sources of Vegetable Oils

    • Vegetable oils and fats are found in various parts of plants, but seeds typically have higher concentrations than other parts.
    • Examples include cottonseed oil, linseed oil, sesame oil and castor bean seeds, almonds.

    Biosynthesis of Lipids

    • Acetate reacts with CoA to form acetyl-CoA.
    • Acetyl-CoA is converted to malonyl CoA using carbon dioxide.
    • Malonyl CoA reacts with acetyl CoA to form a 5-carbon intermediate.
    • The intermediate undergoes reduction and elimination of carbon dioxide to produce butyryl-CoA.
    • The process repeats, creating fatty acids with an even number of carbon atoms.
    • The malonyl portion of malonyl-CoA acts as the source of the 2-carbon units.

    Hardening and Polymerization of Oils

    • Unsaturated fixed oils and their glycerides can add hydrogen (H2) to their double bonds in the presence of catalyst.
    • This property is used to harden oils in the fat industry.
    • Fat hardening process makes fats less susceptible to rancidification.
    • Fat polymerization involves heating oils in an inert atmosphere.
    • Prolonged heating causes unsaturated components to react and form more saturated or cyclic structures.
    • Polymerized oils don't develop rancidity.
    • Hydrogenation of cheap oils (like cotton oil, corn oil, soybean oil) converts them from liquid to solid forms, similar to lard or butter.

    Drying Properties

    • Some fixed oils are classified as drying, semidrying, or nondrying based on their ability to absorb oxygen.
    • Oxygen saturates the double bonds, forming oxides that can polymerize and form hard films (drying oils).
    • Semidrying oils contain both oleic and linoleic glycerides, while nondrying oils have a high amount of oleic acid in their glycerides.

    Evaluation of Fixed Oils and Fats

    • The United States Pharmacopeia and the National Formulary include tests to determine the identity, quality, and purity of fixed oils and fats.
    • These tests are based on the oils' chemical constitutions.

    Testing Methods (Physical Constants)

    • Acid value/number: Amount of free fatty acid in the oil (mg of KOH needed for neutralization).
    • Saponification value: Amount of KOH needed to saponify completely 1gm of fat or oil (mg of KOH needed to neutralize free acids and saponify esters in 1gm).
    • Iodine number: Measures the degree of unsaturation (grams of iodine absorbed by 100 gm of substance).
    • Other constants: Melting point, specific gravity, refractive index are used also for identifiying and measuring quality of different fixed oils and fats.

    Rancidity

    • Rancidity is a transformation in oils and fats during storage where a new compound is formed which often changes the oil's consistency, taste, and smell.
    • Rancidity is caused by volatile, bad-smelling acids and aldehydes.
    • These compounds result from oxygen attack at reactive allylic positions in the fat molecules.
    • Hydrogenation can slow down the development of rancidity. by decreasing the number of double bonds.
    • Types of rancidity include hydrolytic (due to enzyme lipase) and oxidative (due to unsaturated fatty acids and polymerization).

    Uses of Fixed Oils and Fats

    • In pharmaceuticals, fixed oils and fats are used for their emollient properties (e.g., in ointments, creams, and emulsions).
    • They are also used as vehicles for other medications.
    • In arts and industries, they are used in soap production, drying oil in paints/varnishes, and lubrication.

    Specific examples of Fixed Oils (with uses)

    • Castor oil: Stimulant cathartic; used in soap manufacturing, sometimes has therapeutic properties.

    • Linseed oil: Demulcent and laxative.

    • Olive oil: Used in soaps, plasters, also a demulcent, emollient, laxative, and widely used as salad oil.

    • Cottonseed oil: Used pharmaceutically as a solvent for injections; also used in soapmaking.

    • Sesame oil: Used as a solvent for intramuscular injections also has nutritive, laxative, demulcent, and emollient properties..

    • Cocoa butter: Pharmaceutically used as a suppository base.

    • Lard: Purified internal fat of abdomen; emollient, used as base for ointment

    • Lanolin: Purified, fat-like substance from sheep wool; ingredient in skin creams and cosmetics.

    Waxes

    • Waxes are esters formed from high-molecular-weight, straight-chain acids and high-molecular-weight, primary, straight chain alcohols.
    • In plants, waxes are found on outer cell walls of epidermal tissue, especially in fruits and leaves.
    • Waxes protect plants from losing or gaining water.
    • Insects also secrete waxes.
    • Waxes are used in pharmaceuticals to harden ointments and creams; also for protective coatings.
    • Beeswax: A purified wax from bee honeycombs; used as stiffening agent, in yellow ointments, and as a base for plasters; also found in some polishes.

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