Lipid Profile Lecture by Mrs.K.Losana

Apo(a) exhibits a significant sequence homology with apolipoprotein B-100

Lipoprotein (a) contains mostly triglycerides and free fatty acids as its major lipids.

Immunoturbidimetry is the most common method used for measuring Apo B-100 and Apo A1.

Immunonephelometry requires spectrophotometric analyzers for the measurement of lipoproteins.

The emerging markers for better assessing cardiovascular disease include plasma concentration of amino acids and homocysteine.

Lipoprotein (a) Turbidimetric method is not commonly used due to the lack of commercial availability of anti sera and reference sera.

Lipids are polar molecules soluble in water.

Lipids serve as hormones, energy sources, and structural components in cell membranes.

Lipids and lipoproteins are involved in the development of a condition called ATHEROSCLEROSIS.

According to the lecture, lipids are subdivided into five groups based on their chemical structure.

Ultracentrifugation is a method used in the measurement of lipid profile parameters.

Electrophoresis is not a technique used in the measurement of lipids.

Ultracentrifugation is a method used in the 2nd generation of lipid analysis techniques.

Selective precipitation can be negatively affected by high levels of triglycerides (>400mg/dL).

Immuno separation involves the use of monoclonal antibodies to separate lipoproteins.

Homogenous assays for lipid analysis require fasting before conducting the test.

Lipoprotein (a) possesses apo B-100 and has similar lipid compositions to HDL.

Selective precipitation methods involve measuring LDL by estimating TC values in both serum and the supernatant.