Limited Role of F-18 FDG PET/CT in Certain Cancers

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Which type of cancer is only 50% imaged with FDG-PET due to high levels of phosphatase?

Bladder cancer

Prostate cancer

Renal cell carcinoma (RCC)

Hepatocellular carcinoma (HCC) (correct)

What percentage of renal cell carcinomas are FDG-avid?

50% (correct)

25%

90%

75%

Why is detection of ureteral or bladder lesions extremely limited with FDG-PET?

Due to inadequate imaging technology

Due to low FDG uptake by the tumors

Due to high levels of phosphatase in the tumors

Due to surrounding high urinary FDG activity (correct)

In which type of prostate cancer is FDG-PET reserved for assessing treatment response?

Aggressive castration-resistant prostate cancer Signup and view all the answers

What type of tumors tend to have low FDG uptake or are non-FDG-avid?

Well-differentiated or mucinous cell type tumors, lung adenocarcinoma, and carcinoid tumors Signup and view all the answers

What is the new first-line diagnostic imaging modality for neuroendocrine tumors?

Gallium-68 DOTATATE (GaTate) PET/CT Signup and view all the answers

What is the primary benefit of using DOTATATE and FDG PET/CT in tandem?

To provide a comprehensive view of both well-differentiated and poorly differentiated tumors Signup and view all the answers

Which of the following PET radiotracers is FDA-approved for imaging biochemically recurrent prostate cancer with high PSA levels?

Carbon-11/F-18 choline Signup and view all the answers

What is the primary mechanism of F-18 fluciclovine (Axumin) in prostate cancer imaging?

Targeting amino acid transporters Signup and view all the answers

Which PET radiotracer is highly sensitive for the detection of prostate cancer bone metastases?

F-18 sodium fluoride (F-18 NaF) Signup and view all the answers

What is the limitation of F-18 sodium fluoride (F-18 NaF) in prostate cancer imaging?

Both A and B Signup and view all the answers

What is the primary characteristic of Tc-99m DTPA and Tc-99m pertechnetate?

They are transient perfusion agents Signup and view all the answers

Limited Role of F-18 FDG PET/CT in Certain Cancers

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Questions and Answers

Which type of cancer is only 50% imaged with FDG-PET due to high levels of phosphatase?

What percentage of renal cell carcinomas are FDG-avid?

Why is detection of ureteral or bladder lesions extremely limited with FDG-PET?

In which type of prostate cancer is FDG-PET reserved for assessing treatment response?

What type of tumors tend to have low FDG uptake or are non-FDG-avid?

What is the new first-line diagnostic imaging modality for neuroendocrine tumors?

What is the primary benefit of using DOTATATE and FDG PET/CT in tandem?

Which of the following PET radiotracers is FDA-approved for imaging biochemically recurrent prostate cancer with high PSA levels?

What is the primary mechanism of F-18 fluciclovine (Axumin) in prostate cancer imaging?

Which PET radiotracer is highly sensitive for the detection of prostate cancer bone metastases?

What is the limitation of F-18 sodium fluoride (F-18 NaF) in prostate cancer imaging?

What is the primary characteristic of Tc-99m DTPA and Tc-99m pertechnetate?

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