12 Questions
Which type of cancer is only 50% imaged with FDG-PET due to high levels of phosphatase?
Hepatocellular carcinoma (HCC)
What percentage of renal cell carcinomas are FDG-avid?
50%
Why is detection of ureteral or bladder lesions extremely limited with FDG-PET?
Due to surrounding high urinary FDG activity
In which type of prostate cancer is FDG-PET reserved for assessing treatment response?
Aggressive castration-resistant prostate cancer
What type of tumors tend to have low FDG uptake or are non-FDG-avid?
Well-differentiated or mucinous cell type tumors, lung adenocarcinoma, and carcinoid tumors
What is the new first-line diagnostic imaging modality for neuroendocrine tumors?
Gallium-68 DOTATATE (GaTate) PET/CT
What is the primary benefit of using DOTATATE and FDG PET/CT in tandem?
To provide a comprehensive view of both well-differentiated and poorly differentiated tumors
Which of the following PET radiotracers is FDA-approved for imaging biochemically recurrent prostate cancer with high PSA levels?
Carbon-11/F-18 choline
What is the primary mechanism of F-18 fluciclovine (Axumin) in prostate cancer imaging?
Targeting amino acid transporters
Which PET radiotracer is highly sensitive for the detection of prostate cancer bone metastases?
F-18 sodium fluoride (F-18 NaF)
What is the limitation of F-18 sodium fluoride (F-18 NaF) in prostate cancer imaging?
Both A and B
What is the primary characteristic of Tc-99m DTPA and Tc-99m pertechnetate?
They are transient perfusion agents
This quiz covers the types of cancers where F-18 FDG PET/CT imaging has limited diagnostic value, including Hepatocellular carcinoma, Renal cell carcinoma, and bladder cancer. Understand the reasons behind the limitations of FDG-PET in these cancers. Test your knowledge and learn more about the role of PET/CT in cancer diagnosis.
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