CT Imaging and PET-CT Quiz

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Questions and Answers

What is the primary advantage of using F-18 fluorodeoxyglucose (FDG) in positron emission tomography (PET) compared to Single-photon emission computed tomography (SPECT)?

  • Better anatomical localization
  • Reduced scan time
  • Higher contrast and spatial resolution (correct)
  • Lower radiation exposure

In PET-CT imaging for cancer detection, what is the main reason for combining PET with CT?

  • To speed up the scanning process
  • To improve anatomical localization and provide detailed metabolic information (correct)
  • To reduce patient discomfort
  • To decrease radiation exposure

How does Single-photon emission computed tomography (SPECT) differ from Positron emission tomography (PET) in terms of the radioisotopes used?

  • PET uses gamma-emitting radioisotopes (correct)
  • PET uses tracers like technetium-99m
  • SPECT uses tracers with better contrast and resolution
  • SPECT uses positron-emitting radioisotopes

For normal tissue and organ mapping in PET-CT, what advantage does Single-photon emission computed tomography (SPECT) have over Positron emission tomography (PET)?

<p>Better spatial resolution and contrast (A)</p> Signup and view all the answers

In the context of PET-CT imaging, what role does attenuation correction play in the scanning process?

<p>Improves the accuracy of metabolic and functional information (B)</p> Signup and view all the answers

What is the primary purpose of using PET-CT imaging in cancer detection?

<p>To measure the metabolic activity of cells in the body (A)</p> Signup and view all the answers

How can PET-CT imaging be used to stage cancer?

<p>By assessing the extent of disease spread to other organs (C)</p> Signup and view all the answers

What is the role of PET-CT imaging in evaluating the response to cancer treatment?

<p>To assess changes in the metabolic activity of the tumor in response to treatment (D)</p> Signup and view all the answers

How is a PET-CT procedure performed for cancer imaging?

<p>The patient is injected with a radioactive tracer, then scanned using a PET camera (B)</p> Signup and view all the answers

How can PET-CT imaging be used to map normal tissues and organs in the body?

<p>By identifying areas of increased metabolic activity in healthy tissues (B)</p> Signup and view all the answers

What is the significance of the radioactive tracer used in PET-CT imaging?

<p>It helps the PET camera detect and localize the tumor (B)</p> Signup and view all the answers

What is the primary use of PET-CT imaging in cancer management?

<p>All of the above (D)</p> Signup and view all the answers

How does PET-CT imaging help in staging cancer?

<p>All of the above (D)</p> Signup and view all the answers

Which radioactive material is commonly used in PET-CT imaging for cancer detection?

<p>Fluorine-18 fluorodeoxyglucose (F-18 FDG) (B)</p> Signup and view all the answers

What is the primary advantage of PET-CT imaging over other imaging techniques?

<p>It focuses on metabolic processes within the body (A)</p> Signup and view all the answers

Which of the following is NOT a common use of PET-CT imaging?

<p>Detecting bone fractures (D)</p> Signup and view all the answers

How is the radioactive material administered to the patient during a PET-CT scan?

<p>Any of the above methods can be used (D)</p> Signup and view all the answers

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Study Notes

SPECT-CT Reconstruction

  • Projection data from cameras is reconstructed into 3D images in axial slices
  • SPECT-CT provides attenuation correction and higher resolution anatomical localization

SPECT vs PET

  • SPECT and PET are nuclear medicine imaging techniques that provide metabolic and functional information
  • They can be combined with CT and MRI to provide detailed anatomical and metabolic information

Positron Emission Tomography (PET)

  • Uses positron-emitting radioisotope (tracer) such as F-18 fluorodeoxyglucose (FDG)
  • Provides better contrast and spatial resolution compared to SPECT
  • Has a ring of multiple detectors

Single-Photon Emission Computed Tomography (SPECT)

  • Uses gamma-emitting radioisotope (tracer) such as technetium-99m, iodine-123, or iodine-131
  • Provides poorer contrast and spatial resolution compared to PET
  • Usually uses one large crystal-based detector

Positron Emission Tomography/ PET-CT

  • Utilizes the advantages of both PET and CT
  • Nuclear medicine uses small amounts of radioactive material called radiotracers to diagnose, evaluate, and treat various diseases
  • Radiotracers accumulate in tumors or regions of inflammation and can bind to specific proteins in the body

Radiotracers

  • The most common radiotracer is 2-[F-18]fluoro-2-deoxy-D-glucose (FDG), a molecule similar to glucose
  • Fluorine-18 is an unstable radioisotope with a half-life of approximately 110 minutes
  • Cancer cells are more metabolically active and may absorb glucose at a higher rate

PET-CT Procedure

  • Ordinary x-ray exams pass x-rays through the body to create an image
  • Radioactive materials (F-18 fluorodeoxyglucose) are injected intravenously, or swallowed or inhaled as a gas
  • The material accumulates in the area under examination, giving off gamma rays
  • Special cameras detect this energy and create pictures with the help of a computer

Uses of PET-CT

  • Detect cancer and/or make a diagnosis
  • Determine whether a cancer has spread in the body
  • Stage cancer which potentially can be treated radically
  • Establish baseline staging before commencing treatment
  • Determine if a cancer has returned after treatment
  • Evaluate prognosis
  • Assess tissue metabolism and viability
  • Map normal human brain and heart function
  • Assess response to therapy
  • Evaluate suspected disease recurrence, relapse, and/or residual disease

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