Limited Role of F-18 FDG PET/CT in Certain Cancers

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Which type of cancer has only 50% of its cases that can be imaged with FDG-PET due to high levels of phosphatase?

Renal cell carcinoma

Hepatocellular carcinoma (correct)

Prostate cancer

Bladder cancer

What is the main limitation of using FDG-PET for detecting ureteral or bladder lesions?

High urinary FDG activity (correct)

Low FDG uptake by the tumor

Low sensitivity of FDG-PET for these types of tumors

High levels of phosphatase in the tumor

What is the primary role of FDG-PET in prostate cancer?

Monitoring treatment response in localized prostate cancer

Assessing treatment response of bony metastases in aggressive castration-resistant prostate cancer (correct)

Screening for prostate cancer in high-risk populations

Initial diagnosis of prostate cancer

Which type of tumor tends to have low FDG uptake or is non-FDG-avid?

Well-differentiated or mucinous cell type tumors Signup and view all the answers

What is the half-life of Gallium-68, a generator-produced positron emitter?

68 minutes Signup and view all the answers

What is the new first-line diagnostic imaging modality for neuroendocrine tumors?

DOTATATE PET/CT Signup and view all the answers

What is the characteristic of DOTATATE uptake in tumors?

High uptake in well-differentiated tumors Signup and view all the answers

Which PET radiotracer is FDA-approved for detection of biochemically recurrent prostate cancer?

F-18 fluciclovine (Axumin) Signup and view all the answers

What is the characteristic of F-18 sodium fluoride (F-18 NaF) in detecting prostate cancer bone metastases?

High sensitivity and low specificity Signup and view all the answers

What is the common feature of Tc-99m DTPA and Tc-99m pertechnetate?

They are transient perfusion agents Signup and view all the answers

Why is imaging performed immediately after injection of F-18 fluciclovine (Axumin)?

To limit any significant urinary excretion Signup and view all the answers

What is the enzymatic modification required for Tc-99m ECD?

To be retained in the cell Signup and view all the answers

Limited Role of F-18 FDG PET/CT in Certain Cancers

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Questions and Answers

Which type of cancer has only 50% of its cases that can be imaged with FDG-PET due to high levels of phosphatase?

What is the main limitation of using FDG-PET for detecting ureteral or bladder lesions?

What is the primary role of FDG-PET in prostate cancer?

Which type of tumor tends to have low FDG uptake or is non-FDG-avid?

What is the half-life of Gallium-68, a generator-produced positron emitter?

What is the new first-line diagnostic imaging modality for neuroendocrine tumors?

What is the characteristic of DOTATATE uptake in tumors?

Which PET radiotracer is FDA-approved for detection of biochemically recurrent prostate cancer?

What is the characteristic of F-18 sodium fluoride (F-18 NaF) in detecting prostate cancer bone metastases?

What is the common feature of Tc-99m DTPA and Tc-99m pertechnetate?

Why is imaging performed immediately after injection of F-18 fluciclovine (Axumin)?

What is the enzymatic modification required for Tc-99m ECD?

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