Limited Role of F-18 FDG PET/CT in Certain Cancers
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Limited Role of F-18 FDG PET/CT in Certain Cancers

This quiz covers the types of cancers where F-18 FDG PET/CT imaging has limited effectiveness, including Hepatocellular carcinoma, Renal cell carcinoma, and bladder cancer. Learn about the reasons behind this limited role and how PET/CT can still be useful in detecting metastatic disease. Test your knowledge on the applications of F-18 FDG PET/CT in oncology.

Created by
@ReasonableWonder

Questions and Answers

Which type of cancer has only 50% of its cases that can be imaged with FDG-PET due to high levels of phosphatase?

Hepatocellular carcinoma

What is the main limitation of using FDG-PET for detecting ureteral or bladder lesions?

High urinary FDG activity

What is the primary role of FDG-PET in prostate cancer?

Assessing treatment response of bony metastases in aggressive castration-resistant prostate cancer

Which type of tumor tends to have low FDG uptake or is non-FDG-avid?

<p>Well-differentiated or mucinous cell type tumors</p> Signup and view all the answers

What is the half-life of Gallium-68, a generator-produced positron emitter?

<p>68 minutes</p> Signup and view all the answers

What is the new first-line diagnostic imaging modality for neuroendocrine tumors?

<p>DOTATATE PET/CT</p> Signup and view all the answers

What is the characteristic of DOTATATE uptake in tumors?

<p>High uptake in well-differentiated tumors</p> Signup and view all the answers

Which PET radiotracer is FDA-approved for detection of biochemically recurrent prostate cancer?

<p>F-18 fluciclovine (Axumin)</p> Signup and view all the answers

What is the characteristic of F-18 sodium fluoride (F-18 NaF) in detecting prostate cancer bone metastases?

<p>High sensitivity and low specificity</p> Signup and view all the answers

What is the common feature of Tc-99m DTPA and Tc-99m pertechnetate?

<p>They are transient perfusion agents</p> Signup and view all the answers

Why is imaging performed immediately after injection of F-18 fluciclovine (Axumin)?

<p>To limit any significant urinary excretion</p> Signup and view all the answers

What is the enzymatic modification required for Tc-99m ECD?

<p>To be retained in the cell</p> Signup and view all the answers

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