Life Sciences MCQs: Major Histocompatibility Complex
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Questions and Answers

Chediak-Higashi syndrome is caused due to deficiency of which of the following?

  • Nutrophils
  • Basophils
  • Nk cells (correct)
  • Mast cell
  • Which of the following is NOT a polymorphonuclear leukocyte?

  • Mast cell
  • Macrophages (correct)
  • Basophils
  • Eosinophils
  • Which of the following cells has a high affinity receptor for IgE?

  • Eosinophils
  • Dendritic cell
  • Basophils
  • Mast cells (correct)
  • Which macrophages are associated with the central nervous system?

    <p>Microglial cells</p> Signup and view all the answers

    Which molecule is constitutively expressed on dendritic cells?

    <p>Class II MHC</p> Signup and view all the answers

    Which dendritic cell does not function as an antigen-presenting cell?

    <p>Lymphoid dendritic cell</p> Signup and view all the answers

    Study Notes

    Major Histocompatibility Complex (MHC)

    • MHC is a tight cluster of linked genes.

    Immune System Cells

    • Chediak-Higashi syndrome is caused by a deficiency of NK cells.
    • Polymorphonuclear leukocytes include:
      • Eosinophils
      • Basophils
      • Not macrophages
    • Mast cells have a high affinity receptor for IgE.
    • Microglial cells are macrophages associated with the central nervous system.

    Antigen Presentation

    • Dendritic cells constitutively express Class II MHC molecules.
    • Antigen-presenting cells (APCs) include:
      • Dendritic cells
      • Not lymphoid dendritic cells
    • Follicular dendritic cells do not function as antigen-presenting cells.

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    Description

    Practice life sciences multiple choice questions on Major Histocompatibility Complex, covering topics such as immuno-deficiency syndromes and types of leukocytes.

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