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Questions and Answers
Chediak-Higashi syndrome is caused due to deficiency of which of the following?
Chediak-Higashi syndrome is caused due to deficiency of which of the following?
- Nutrophils
- Basophils
- Nk cells (correct)
- Mast cell
Which of the following is NOT a polymorphonuclear leukocyte?
Which of the following is NOT a polymorphonuclear leukocyte?
- Mast cell
- Macrophages (correct)
- Basophils
- Eosinophils
Which of the following cells has a high affinity receptor for IgE?
Which of the following cells has a high affinity receptor for IgE?
- Eosinophils
- Dendritic cell
- Basophils
- Mast cells (correct)
Which macrophages are associated with the central nervous system?
Which macrophages are associated with the central nervous system?
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Which molecule is constitutively expressed on dendritic cells?
Which molecule is constitutively expressed on dendritic cells?
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Which dendritic cell does not function as an antigen-presenting cell?
Which dendritic cell does not function as an antigen-presenting cell?
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Study Notes
Major Histocompatibility Complex (MHC)
- MHC is a tight cluster of linked genes.
Immune System Cells
- Chediak-Higashi syndrome is caused by a deficiency of NK cells.
- Polymorphonuclear leukocytes include:
- Eosinophils
- Basophils
- Not macrophages
- Mast cells have a high affinity receptor for IgE.
- Microglial cells are macrophages associated with the central nervous system.
Antigen Presentation
- Dendritic cells constitutively express Class II MHC molecules.
- Antigen-presenting cells (APCs) include:
- Dendritic cells
- Not lymphoid dendritic cells
- Follicular dendritic cells do not function as antigen-presenting cells.
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