Life Sciences MCQs: Major Histocompatibility Complex

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Questions and Answers

Chediak-Higashi syndrome is caused due to deficiency of which of the following?

Nutrophils
Basophils
Nk cells (correct)
Mast cell

Which of the following is NOT a polymorphonuclear leukocyte?

Mast cell
Macrophages (correct)
Basophils
Eosinophils

Which of the following cells has a high affinity receptor for IgE?

Eosinophils
Dendritic cell
Basophils
Mast cells (correct)

Which macrophages are associated with the central nervous system?

Microglial cells (D) Signup and view all the answers

Which molecule is constitutively expressed on dendritic cells?

Class II MHC (B) Signup and view all the answers

Which dendritic cell does not function as an antigen-presenting cell?

Lymphoid dendritic cell (B) Signup and view all the answers

Study Notes

Major Histocompatibility Complex (MHC)

MHC is a tight cluster of linked genes.

Immune System Cells

Chediak-Higashi syndrome is caused by a deficiency of NK cells.
Polymorphonuclear leukocytes include:
- Eosinophils
- Basophils
- Not macrophages
Mast cells have a high affinity receptor for IgE.
Microglial cells are macrophages associated with the central nervous system.

Antigen Presentation

Dendritic cells constitutively express Class II MHC molecules.
Antigen-presenting cells (APCs) include:
- Dendritic cells
- Not lymphoid dendritic cells
Follicular dendritic cells do not function as antigen-presenting cells.

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Description

Practice life sciences multiple choice questions on Major Histocompatibility Complex, covering topics such as immuno-deficiency syndromes and types of leukocytes.