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Biol 121 overall
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Biol 121 overall

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Questions and Answers

What is the characteristic of the viral genome in the Baltimore system of virus classification?

  • It is already in the form of mRNA
  • It can be directly translated into protein
  • It must be converted into mRNA which can be read by ribosomes (correct)
  • It can be directly transcribed into mRNA
  • What is the primary mechanism by which viruses attach to host cells during the entry stage?

  • Binding to receptors on the host cell surface (correct)
  • Fusion of envelope with host membrane
  • Injection of nucleic acid
  • Endocytosis
  • What is the term for the process by which viruses release their genetic material into the host cell?

  • Endocytosis
  • Fusion of envelope with host membrane
  • Transcription
  • Injection of nucleic acid (correct)
  • During which stage of the virus life cycle is the synthesis of mRNA occurs?

    <p>Replication</p> Signup and view all the answers

    What is the result of the latent infection pathway?

    <p>Lytic infection</p> Signup and view all the answers

    What is the characteristic of the viral genome in the +dsDNA category of the Baltimore system?

    <p>It is a double-stranded DNA</p> Signup and view all the answers

    What is the primary function of viral glycoprotein during the exit stage?

    <p>To insert viral glycoprotein on the surface of the host membrane</p> Signup and view all the answers

    What is the term for the process by which viruses release their genetic material from the host cell?

    <p>Lysis</p> Signup and view all the answers

    What is the primary mechanism by which lysogenic phages integrate into the host's chromosome?

    <p>By producing repressor protein that blocks lytic genes</p> Signup and view all the answers

    What is the purpose of using bacteriophage enzyme in biomedicine?

    <p>To control the amount of bacteria in the environment</p> Signup and view all the answers

    What is the function of the virion capsid structure in viruses?

    <p>To protect the viral genome from the host's immune system</p> Signup and view all the answers

    During the replication cycle of bacteriophages, what is the primary function of the maturation stage?

    <p>To release new virions from the host cell</p> Signup and view all the answers

    What is the primary advantage of using bacteriophages in biomedicine?

    <p>To control the amount of bacteria in the environment</p> Signup and view all the answers

    What is the primary difference between lytic and lysogenic phages?

    <p>Lytic phages kill the host cell, while lysogenic phages integrate into the host's chromosome</p> Signup and view all the answers

    What is the purpose of the International Committee on Taxonomy of Viruses (ICTV)?

    <p>To classify viruses based on their molecular composition</p> Signup and view all the answers

    What is the primary function of the adsorption stage in the bacteriophage life cycle?

    <p>To bind to the host cell's receptors</p> Signup and view all the answers

    What is the primary function of the capsid in a virus?

    <p>To protect the nucleic acid from being digested</p> Signup and view all the answers

    What type of virus can infect other viruses?

    <p>Virophage</p> Signup and view all the answers

    Which of the following is NOT a type of host for viruses?

    <p>Virus</p> Signup and view all the answers

    What is the purpose of penicillin in biomedicine?

    <p>To act as an antibiotic</p> Signup and view all the answers

    What is the term for the extracellular virus particle?

    <p>Virion</p> Signup and view all the answers

    What is the term for the process by which a virus infects a host cell and replicates?

    <p>Replication</p> Signup and view all the answers

    What is the shape of the capsid of some viruses?

    <p>All of the above</p> Signup and view all the answers

    What is the purpose of statin in biomedicine?

    <p>To inhibit the biosynthesis of cholesterol</p> Signup and view all the answers

    What is the term for the viable cell that doesn't grow in conventional media?

    <p>Viable but non-culturable bacteria</p> Signup and view all the answers

    What is the method of counting cells that involves forming colonies on a solid medium?

    <p>Culturable count</p> Signup and view all the answers

    What is the term for the environmental factor that affects bacterial growth, and has an optimal range for different bacteria?

    <p>Temperature</p> Signup and view all the answers

    How do bacteria divide during the exponential growth phase?

    <p>Binary fission</p> Signup and view all the answers

    What is the term for the type of bacteria that uses light energy for metabolism?

    <p>Phototrophs</p> Signup and view all the answers

    What is the method of counting cells that involves using a fluorescent dye?

    <p>Viable count</p> Signup and view all the answers

    What is the term for the type of bacteria that lives in habitats with high salt concentrations?

    <p>Halophiles</p> Signup and view all the answers

    What is the method of measuring bacterial growth that involves serial dilutions and plating?

    <p>Serial dilution</p> Signup and view all the answers

    What is a characteristic feature of Archaea?

    <p>They have a proteinaceous coat</p> Signup and view all the answers

    What is the function of the cell membrane in microbes?

    <p>To facilitate nutrient exchange and respiration</p> Signup and view all the answers

    What is the function of flagella in microbes?

    <p>To facilitate locomotion</p> Signup and view all the answers

    What is the function of the cell wall in microbes?

    <p>To provide structural support and maintain shape</p> Signup and view all the answers

    What is the function of plasmids in microbes?

    <p>To carry genes that provide selective advantage</p> Signup and view all the answers

    What is the function of endospores in microbes?

    <p>To survive for long periods under unfavourable conditions</p> Signup and view all the answers

    What is the characteristic of the gram-positive cell wall?

    <p>It has a thicker peptidoglycan layer</p> Signup and view all the answers

    What is the function of fimbriae and pili in microbes?

    <p>To facilitate recognition and attachment</p> Signup and view all the answers

    What is the primary function of calcium dipicolinate in Cyanobacteria?

    <p>Binds free water and helps dehydrate cells</p> Signup and view all the answers

    Which type of culture media has an exact chemical composition?

    <p>Chemically defined media</p> Signup and view all the answers

    What is the primary characteristic of micronutrients in bacterial nutrition?

    <p>Small amounts required</p> Signup and view all the answers

    What is the primary function of the lag phase in bacterial growth?

    <p>Cell adaptation to new environment</p> Signup and view all the answers

    What is the primary purpose of using nutrient agar plates in bacterial growth?

    <p>Purification of bacterial cultures</p> Signup and view all the answers

    What is the primary characteristic of bacterial growth in batch culture?

    <p>Closed system with limited nutrient supply</p> Signup and view all the answers

    Which of the following is NOT a characteristic of Cyanobacteria?

    <p>Requires large amounts of micronutrients</p> Signup and view all the answers

    What is the primary function of the stationary phase in bacterial growth?

    <p>Cell growth slows down and reaches equilibrium</p> Signup and view all the answers

    What is the primary characteristic of a viable but non-culturable bacterium?

    <p>It is unable to grow in any medium</p> Signup and view all the answers

    What is the primary advantage of using direct microscopic count to measure bacterial growth?

    <p>It is a fast and easy method</p> Signup and view all the answers

    What is the primary characteristic of a heterotrophic bacterium?

    <p>It is unable to produce its own food and relies on external sources</p> Signup and view all the answers

    What is the primary purpose of serial dilution in measuring bacterial growth?

    <p>To obtain a culturable count of bacteria</p> Signup and view all the answers

    What is the primary environmental factor that affects bacterial growth and has an optimal range for different bacteria?

    <p>All of the above</p> Signup and view all the answers

    What is the primary characteristic of a phototrophic bacterium?

    <p>It is able to produce its own food using light energy</p> Signup and view all the answers

    What is the primary method of counting cells that involves using a fluorescent dye?

    <p>Viable count</p> Signup and view all the answers

    What is the primary characteristic of a halophilic bacterium?

    <p>It is able to grow in habitats with high salt concentrations</p> Signup and view all the answers

    What is the impact of high salt concentration on water activity?

    <p>Decreases water activity through osmosis</p> Signup and view all the answers

    What is the primary difference between opportunistic and primary pathogens?

    <p>Primary pathogens cause diseases in healthy individuals, while opportunistic pathogens cause diseases in individuals with impaired immune systems</p> Signup and view all the answers

    What is the process by which bacterial pathogens establish a stable population in the host?

    <p>Colonization</p> Signup and view all the answers

    What is the term for the ability of a pathogen to cause disease?

    <p>Pathogenicity</p> Signup and view all the answers

    What is the term for the degree or intensity of pathogenicity?

    <p>Virulence</p> Signup and view all the answers

    What is the environment where bacterial pathogens live and reproduce in large amounts?

    <p>Reservoir</p> Signup and view all the answers

    What is the process by which bacteria attach to the host surface?

    <p>Adherence</p> Signup and view all the answers

    What is the term for the type of bacteria that lives in habitats with high salt concentrations?

    <p>Halophile</p> Signup and view all the answers

    What is the primary advantage of a higher SA/Vol ratio in microbial cells?

    <p>Increased rate of nutrient exchange and growth</p> Signup and view all the answers

    What is the function of the proton motive force in microbial cells?

    <p>Energy conservation during respiration</p> Signup and view all the answers

    Which of the following is a characteristic of Gram-positive cell walls?

    <p>Presence of a thick peptidoglycan layer</p> Signup and view all the answers

    What is the primary function of plasmids in microbial cells?

    <p>Carrying genes for antibiotic resistance</p> Signup and view all the answers

    What is the primary advantage of endospores in microbial cells?

    <p>Survival during unfavourable conditions</p> Signup and view all the answers

    What is the primary function of fimbriae and pili in microbial cells?

    <p>Recognition and attachment to surfaces</p> Signup and view all the answers

    Which of the following is a characteristic of the exponential growth phase in microbial cells?

    <p>Increasing growth rate</p> Signup and view all the answers

    What is the primary method of counting microbial cells that involves forming colonies on a solid medium?

    <p>Plate counting</p> Signup and view all the answers

    What is the characteristic of the cell wall of fungi?

    <p>Made of chitin and polysaccharides</p> Signup and view all the answers

    What is the function of enzyme secretion in fungi?

    <p>To digest and absorb organic material</p> Signup and view all the answers

    What is the characteristic of yeasts?

    <p>Single-celled, spherical and asexually reproduced</p> Signup and view all the answers

    What is the function of hyphae in fungi?

    <p>To absorb nutrients from the environment</p> Signup and view all the answers

    What is the characteristic of dimorphic fungi?

    <p>They can transition between yeast and mold forms</p> Signup and view all the answers

    What is the function of sporangia in zygomycetes?

    <p>To produce asexual spores</p> Signup and view all the answers

    What is the characteristic of fungi nutrition?

    <p>They are heterotrophic and absorb nutrients from their surroundings</p> Signup and view all the answers

    What is the mode of reproduction in yeast?

    <p>Asexual reproduction by budding</p> Signup and view all the answers

    What is the primary function of calcium dipicolinate in Cyanobacteria?

    <p>Bind free water and help dehydrate cells</p> Signup and view all the answers

    Which type of culture media has an exact chemical composition?

    <p>Chemically defined media</p> Signup and view all the answers

    What is the primary characteristic of micronutrients in bacterial nutrition?

    <p>Required in small quantities</p> Signup and view all the answers

    What is the primary function of the lag phase in bacterial growth?

    <p>Cell adaptation to new environment</p> Signup and view all the answers

    What is the primary purpose of using nutrient agar plates?

    <p>To purify bacterial cultures</p> Signup and view all the answers

    What is the primary characteristic of bacterial growth in batch culture?

    <p>Closed system with limited nutrients</p> Signup and view all the answers

    What is the assumption made in the culturable count method of measuring bacterial growth?

    <p>Culturable cells will grow and divide to yield one colony</p> Signup and view all the answers

    What is the term for the type of bacteria that uses light energy for metabolism?

    <p>Phototrophs</p> Signup and view all the answers

    What is the primary function of the stationary phase in bacterial growth?

    <p>Nutrient depletion and cell maintenance</p> Signup and view all the answers

    What is the primary difference between total count and viable count in cell counting?

    <p>Total count includes dead cells, viable count only includes live cells</p> Signup and view all the answers

    What is the primary characteristic of a viable but non-culturable bacterium?

    <p>Does not grow on any medium</p> Signup and view all the answers

    What is the purpose of serial dilution in measuring bacterial growth?

    <p>To dilute the culture to a suitable concentration for plating</p> Signup and view all the answers

    What is the primary characteristic of a viable but non-culturable bacterium?

    <p>It is viable but does not grow in conventional media</p> Signup and view all the answers

    What is the primary advantage of using direct microscopic count to measure bacterial growth?

    <p>It is faster and easier than other methods</p> Signup and view all the answers

    What is the term for the type of bacteria that lives in habitats with high salt concentrations?

    <p>Halophiles</p> Signup and view all the answers

    What is the primary characteristic of bacterial growth in the exponential phase?

    <p>Growth rate increases exponentially</p> Signup and view all the answers

    What is the primary function of endospores in microbes?

    <p>To survive for long periods under unfavourable conditions</p> Signup and view all the answers

    What is the primary characteristic of the lag phase in bacterial growth?

    <p>Cell adaptation to new environment</p> Signup and view all the answers

    What is the primary function of bacterial fission?

    <p>To divide and produce new cells</p> Signup and view all the answers

    What type of culture media has an exact chemical composition?

    <p>Defined media</p> Signup and view all the answers

    What is the primary characteristic of micronutrients in bacterial nutrition?

    <p>Required in small quantities</p> Signup and view all the answers

    What is the primary function of the cell membrane in microbes?

    <p>To regulate nutrient uptake</p> Signup and view all the answers

    What is the primary characteristic of a viable but non-culturable bacterium?

    <p>Cannot grow on any medium</p> Signup and view all the answers

    What is the primary function of the cell wall in microbes?

    <p>To provide structural support</p> Signup and view all the answers

    What is the primary purpose of the lag phase in bacterial growth?

    <p>Adaptation to environment and enzyme production</p> Signup and view all the answers

    What type of culture media has an exact chemical composition?

    <p>Defined media</p> Signup and view all the answers

    What is the primary characteristic of bacterial growth in batch culture?

    <p>Exponential growth followed by decline</p> Signup and view all the answers

    What is the function of calcium dipicolinate in Cyanobacteria?

    <p>Sporulation</p> Signup and view all the answers

    What is the primary function of fimbriae and pili in microbes?

    <p>Adherence to host cells</p> Signup and view all the answers

    What is the primary advantage of using direct microscopic count to measure bacterial growth?

    <p>Accurate cell count and viability assessment</p> Signup and view all the answers

    What is the primary characteristic of a viable but non-culturable bacterium?

    <p>Metabolic activity without cell division</p> Signup and view all the answers

    What is the primary function of the stationary phase in bacterial growth?

    <p>Cell maintenance and survival</p> Signup and view all the answers

    What is the purpose of the formation of spores in fungi?

    <p>To disperse and colonize new areas</p> Signup and view all the answers

    During which growth phase do fungi undergo rapid cell division and produce aerial extensions?

    <p>Log phase</p> Signup and view all the answers

    What is the primary mechanism of cell division in yeasts?

    <p>Budding</p> Signup and view all the answers

    What type of culture media is used to grow fungi that require specific nutrients?

    <p>Defined media</p> Signup and view all the answers

    What is the primary function of chitin in fungal cell walls?

    <p>To provide structural support</p> Signup and view all the answers

    Which type of fungi has a heterotrophic mode of nutrition?

    <p>Saprophytes</p> Signup and view all the answers

    What is the primary function of hyphae in filamentous fungi?

    <p>To absorb nutrients</p> Signup and view all the answers

    Which type of fungi has a diploid state during zygospore formation?

    <p>Zygomycetes</p> Signup and view all the answers

    Cyanobacteria are sensitive to extreme conditions.

    <p>False</p> Signup and view all the answers

    Nutrient agar plates are used for the purification of bacterial cultures.

    <p>True</p> Signup and view all the answers

    Bacteria in the stationary phase are in a state of rapid growth.

    <p>False</p> Signup and view all the answers

    Macronutrients are required in small quantities for bacterial growth.

    <p>False</p> Signup and view all the answers

    Chemically defined media has an exact chemical composition.

    <p>True</p> Signup and view all the answers

    The lag phase is the period of rapid bacterial growth.

    <p>False</p> Signup and view all the answers

    Micronutrients are required in large quantities for bacterial growth.

    <p>False</p> Signup and view all the answers

    Batch culture is an open system, where nutrients can be added or removed.

    <p>False</p> Signup and view all the answers

    Binary fission of bacteria results in four daughter cells.

    <p>False</p> Signup and view all the answers

    The viable count of bacteria measures the total number of bacteria in a sample.

    <p>False</p> Signup and view all the answers

    Culturable count of bacteria is the same as viable count.

    <p>False</p> Signup and view all the answers

    Turbidity measurement is used to measure the growth of bacteria in liquid media.

    <p>True</p> Signup and view all the answers

    Heterotrophs are bacteria that obtain energy from light.

    <p>False</p> Signup and view all the answers

    Serial dilution is a method used to measure bacterial growth.

    <p>True</p> Signup and view all the answers

    Halophiles are bacteria that grow in high-temperature habitats.

    <p>False</p> Signup and view all the answers

    Viable but non-culturable bacteria are bacteria that are dead.

    <p>False</p> Signup and view all the answers

    The lag phase is the stage of bacterial growth where the bacteria divide rapidly.

    <p>False</p> Signup and view all the answers

    The stationary phase is characterized by a decrease in bacterial growth rate due to nutrient depletion.

    <p>True</p> Signup and view all the answers

    Endospores are formed during the exponential growth phase.

    <p>False</p> Signup and view all the answers

    Plasmids are required for bacterial growth and reproduction.

    <p>False</p> Signup and view all the answers

    Nutrient agar plates are used to measure bacterial growth in batch culture.

    <p>False</p> Signup and view all the answers

    The primary function of the cell wall is to provide structural support and maintain the shape of the cell.

    <p>True</p> Signup and view all the answers

    Calcium dipicolinate is involved in the formation of endospores in bacteria.

    <p>False</p> Signup and view all the answers

    The SA/Vol ratio affects the growth rate of bacteria.

    <p>True</p> Signup and view all the answers

    In extreme salt concentrations, water activity increases through osmosis.

    <p>False</p> Signup and view all the answers

    Pathogenicity refers to the degree of toxicity and invasiveness of a pathogen.

    <p>True</p> Signup and view all the answers

    Colonization of a host by a pathogen always leads to disease.

    <p>False</p> Signup and view all the answers

    Opportunistic pathogens can cause disease in individuals with a healthy immune system.

    <p>False</p> Signup and view all the answers

    Bacterial growth in a batch culture follows a linear pattern.

    <p>False</p> Signup and view all the answers

    Endospores are formed by all types of bacteria.

    <p>False</p> Signup and view all the answers

    Nutrient agar plates are an example of a selective culture media.

    <p>False</p> Signup and view all the answers

    Calcium dipicolinate is a characteristic component of bacterial spores.

    <p>True</p> Signup and view all the answers

    Fungi have a peptidoglycan cell wall.

    <p>False</p> Signup and view all the answers

    Yeasts are always multicellular.

    <p>False</p> Signup and view all the answers

    Filamentous fungi have a polarized tip growth.

    <p>True</p> Signup and view all the answers

    Saccharomyces cerevisiae is a type of filamentous fungus.

    <p>False</p> Signup and view all the answers

    Heterotrophs obtain their nutrients by photosynthesis.

    <p>False</p> Signup and view all the answers

    Zygomycetes have septate hyphae.

    <p>False</p> Signup and view all the answers

    Fungi reproduce solely through asexual means.

    <p>False</p> Signup and view all the answers

    Glomus spp. are a type of bacterium.

    <p>False</p> Signup and view all the answers

    Bacterial growth is measured by viable count.

    <p>False</p> Signup and view all the answers

    Halophiles grow in habitats with low salt concentrations.

    <p>False</p> Signup and view all the answers

    Autotrophs obtain energy from light.

    <p>False</p> Signup and view all the answers

    Binary fission is a characteristic of the lag phase.

    <p>False</p> Signup and view all the answers

    Turbidity is a measure of bacterial growth by light absorbance.

    <p>True</p> Signup and view all the answers

    Serial dilution is a method of direct microscopic count.

    <p>False</p> Signup and view all the answers

    Culturable count measures the number of colonies formed on agar plates.

    <p>True</p> Signup and view all the answers

    Viable but non-culturable bacteria do not grow in conventional media.

    <p>True</p> Signup and view all the answers

    Cyanobacteria contain calcium dipicolinate, which helps to dehydrate the cell by releasing free water.

    <p>True</p> Signup and view all the answers

    In batch culture, bacterial growth occurs in an open system with continuous nutrient addition.

    <p>False</p> Signup and view all the answers

    The log phase of bacterial growth is characterized by a slow growth rate.

    <p>False</p> Signup and view all the answers

    Microelements are required in large amounts by bacterial cells.

    <p>False</p> Signup and view all the answers

    Complex media has an exact chemical composition.

    <p>False</p> Signup and view all the answers

    Bacterial cells can grow in the absence of nutrient agar plates.

    <p>True</p> Signup and view all the answers

    The stationary phase of bacterial growth is characterized by a rapid growth rate.

    <p>False</p> Signup and view all the answers

    All bacteria require the same amount of micronutrients for growth.

    <p>False</p> Signup and view all the answers

    Endospores are a type of inclusion found in bacterial cells.

    <p>False</p> Signup and view all the answers

    During the exponential growth phase, bacterial cells divide by binary fission.

    <p>True</p> Signup and view all the answers

    Most alkaliphiles are halotolerant.

    <p>False</p> Signup and view all the answers

    Bacteria can use light energy for metabolism through the process of chemosynthesis.

    <p>False</p> Signup and view all the answers

    Nutrient agar plates are a type of selective media.

    <p>False</p> Signup and view all the answers

    Pathogens can cause diseases in the presence of a healthy immune system.

    <p>False</p> Signup and view all the answers

    Reservoirs are where bacterial pathogens are eliminated.

    <p>False</p> Signup and view all the answers

    The lag phase of bacterial growth is the period of rapid cell division.

    <p>False</p> Signup and view all the answers

    Adherence is the establishment of a stable population of bacteria in the host.

    <p>False</p> Signup and view all the answers

    Fimbriae are involved in the attachment of bacteria to surfaces.

    <p>True</p> Signup and view all the answers

    Spore formation is a type of binary fission in bacteria.

    <p>False</p> Signup and view all the answers

    Opportunistic pathogens can cause diseases in the absence of immune impairment.

    <p>False</p> Signup and view all the answers

    High salt concentration leads to higher water activity.

    <p>False</p> Signup and view all the answers

    Micronutrients are essential for bacterial growth in very large quantities.

    <p>False</p> Signup and view all the answers

    Transfer to the host occurs through indirect host-host transmission only.

    <p>False</p> Signup and view all the answers

    Infection always leads to disease.

    <p>False</p> Signup and view all the answers

    Fungi can produce haploid spores through a process of meiosis.

    <p>True</p> Signup and view all the answers

    Filamentous fungi are typically multicellular.

    <p>True</p> Signup and view all the answers

    Yeasts are always single-celled organisms.

    <p>True</p> Signup and view all the answers

    Fungi can absorb nutrients from their environment through a process of heterotrophy.

    <p>True</p> Signup and view all the answers

    Zygomycetes are the largest phylum of fungi.

    <p>False</p> Signup and view all the answers

    Fungi can reproduce sexually through a process of heterothallism.

    <p>True</p> Signup and view all the answers

    Fungi have a cell wall composed of chitin and polysaccharides.

    <p>True</p> Signup and view all the answers

    Saccharomyces cerevisiae is a type of filamentous fungus.

    <p>False</p> Signup and view all the answers

    Study Notes

    Viral Replication Cycle

    • Adsorption: Virus attaches to receptors
    • Penetration: Inject nucleic acid into host cell
    • Replication: Synthesis of viral material and combine
    • Maturation: Release of new virions
    • Release: Lytic and lysogenic/temperature phage

    Lytic and Lysogenic/Temperature Phage

    • Lytic phage: Kill host cell
    • Lysogenic/Temperature phage:
      • Prophage: Integrate into host’s chromosome
      • Replicates with host cell
      • Stresses → reactivate the lytic cycle

    Phages in Biomedicine

    • EBI: Used on unprocessed foods
    • Bacteriophage enzyme
    • Display of immunodominant region of HBV on bacteriophage H7

    Quantifying Bacteriophage

    • Agar plate with E. coli

    Viruses Benefits and Disadvantages

    • Advantages:
      • Planetary force
      • Control the amount of bacteria
    • Disadvantages:
      • Impact on health
      • Impact of microbes

    Taxonomy for Viruses

    • International Committee on Taxonomy of Viruses (ICTV)
    • Molecular composition of genome
    • Sequence similarity
    • Virion/capsid structure
    • Presence of an envelope
    • Host range
    • Pathogenicity

    Baltimore System of Virus Classification

    • Viral genome must make mRNA which can be read by ribosomes
    • mRNA: +ssRNA (ribosome ready)
    • +dsDNA
    • Complementary: - (minus)

    Infection Pathway

    • Transformation into tumour cell
    • Lysis
    • Persistent infection (Slow release of virus, X cell death)
    • Latent infection (→ Lytic infection)

    Virus Life Cycle

    • Entry: Viruses attach to receptors
    • Replication: Viral protein synthesis of mRNA, viral genome generation
    • Exit:
      • Virus inserts viral glycoprotein on the surface of the membrane
      • Capsid migrates to the cell membrane

    Fungi as Drugs

    • Penicillin (antibiotics)
    • Statin: Inhibit biosynthesis of cholesterol, reduce plasma cholesterol level

    General Properties, Structures, and Hosts of Viruses

    • Viruses: Simple, minuscule, infectious, obligate intracellular parasite comprising genetic material surrounded by a protein coat deprived from a host cell membrane
    • Genetic material of virus: DNA & RNA
    • Virus existence in 2 states:
      • Intracellular virus (After infecting the host cell) [Replication]
      • Extracellular Virion (Outside host cell) [Transmission]

    Shapes of Capsid

    • Helical
    • Polyhedral
    • Binal
    • Function of capsid:
      • Protects nucleic acid from being digested
      • Attaches to the host cell
      • Penetrates host cell membrane

    Cyanobacteria

    • Highly resistant to extreme conditions
    • Contain calcium dipicolinate, which binds free water and helps dehydrate the cell
    • Some cyanobacteria contain iron and have a special protein that protects their DNA, allowing them to orient themselves in magnetic fields

    Bacterial Nutrition and Growth

    • Nutrients provide elements for the synthesis of cell material
    • Macronutrients are required in large amounts and include elements like C, O, H, N, P, S, K, Ca, and Mg
    • Micronutrients are required in small amounts and include elements like Cu, Zn, Ni, V, and Se
    • Bacteria can grow in culture media, which provides all the necessary elements for growth
    • Culture media can be chemically defined, complex, or a nutrient agar plate
    • Bacteria can also grow in liquid media, such as Erlenmeyer flasks or test tubes

    Bacterial Growth Phases

    • Bacterial growth occurs in four phases: lag, log, stationary, and death
    • The lag phase is a period of slow growth, followed by the log phase, where growth is rapid and exponential
    • The stationary phase is where growth slows down due to resource depletion, and the death phase is where cell death occurs
    • Bacterial growth can be measured using direct microscopic count, culturable count, or serial dilution

    Metabolic Classification of Bacteria

    • Bacteria can be classified based on their carbon and energy resources
    • Heterotrophs use organic compounds as their carbon source, while autotrophs use CO2
    • Phototrophs use light as their energy source, while chemotrophs use chemical reactions
    • Environmental factors like oxygen, temperature, pH, and osmolarity can affect bacterial growth and metabolism

    Microbiology

    • Microbiology is the study of organisms that are too small to be seen by the unaided eye
    • Microorganisms can be beneficial or harmful to humans
    • Microbiology involves the study of diseases caused by pathogens, and the control of these diseases through vaccination, antibiotics, and personal hygiene

    Three Domains of Life

    • The three domains of life are Eukaryota, Bacteria, and Archaea
    • Eukaryotes have one or more cells with a nucleus and well-developed intracellular compartments
    • Bacteria are prokaryotic microorganisms that are typically small and simple in structure
    • Archaea are prokaryotes that are similar to bacteria in size and simplicity, but have distinct molecular characteristics

    Cell Structure and Function

    • Cell membrane functions include barrier function, respiration/photosynthesis, and energy conservation
    • Cell wall determines and maintains the shape of the cell, and protects it from osmotic lysis
    • Gram-positive and Gram-negative cell walls have different structures and functions
    • Capsule, fimbriae, and pili are important structures involved in bacterial attachment and protection

    Bacterial Cytoplasm

    • Nucleoid is an irregularly shaped region that contains the genetic material
    • Plasmids are small, closed circular DNA molecules that exist and replicate independently of the chromosome
    • Cellular inclusions are granules of material that are reserved for future use
    • Endospores are highly resistant structures that can survive for long periods of time

    How Bacteria Cause Diseases

    • Most bacteria are harmless, and the host immune system prevents them from causing disease
    • Pathogens are organisms that cause diseases by impairing or interfering with normal physiological activities
    • Pathogenicity is the ability to cause disease, and virulence is the degree of pathogenicity
    • Infection and disease are different, with infection being the presence of a pathogen, and disease being the impairment of normal physiological activities

    Steps in Infectious Diseases

    • The steps in infectious diseases include the reservoir, transfer to host, colonization, adherence, and infection
    • The reservoir is where the bacterial pathogen lives and reproduces, and can be a human, animal, or environment
    • Transfer to host can occur through direct or indirect contact, or through vectors or vehicles

    Fungi

    • Fungi are eukaryotes that are extremely diverse, with cell walls made of chitin and polysaccharides
    • Fungi can be saprophytes, necrophytes, or biotrophs, and can reproduce both sexually and asexually
    • Fungi can be single-celled or multicellular, and can form colonies or mycelium
    • Yeasts are single-celled fungi that reproduce asexually by budding, while filamentous fungi are multicellular and reproduce by forming spores

    Cyanobacteria

    • Highly resistant to extreme conditions
    • Contain calcium dipicolinate, which binds free water and helps dehydrate the cell
    • Some cyanobacteria contain iron and have a special protein that protects their DNA, allowing them to orient themselves in magnetic fields

    Bacterial Nutrition and Growth

    • Nutrients provide elements for the synthesis of cell material
    • Macronutrients are required in large amounts and include elements like C, O, H, N, P, S, K, Ca, and Mg
    • Micronutrients are required in small amounts and include elements like Cu, Zn, Ni, V, and Se
    • Bacteria can grow in culture media, which provides all the necessary elements for growth
    • Culture media can be chemically defined, complex, or a nutrient agar plate
    • Bacteria can also grow in liquid media, such as Erlenmeyer flasks or test tubes

    Bacterial Growth Phases

    • Bacterial growth occurs in four phases: lag, log, stationary, and death
    • The lag phase is a period of slow growth, followed by the log phase, where growth is rapid and exponential
    • The stationary phase is where growth slows down due to resource depletion, and the death phase is where cell death occurs
    • Bacterial growth can be measured using direct microscopic count, culturable count, or serial dilution

    Metabolic Classification of Bacteria

    • Bacteria can be classified based on their carbon and energy resources
    • Heterotrophs use organic compounds as their carbon source, while autotrophs use CO2
    • Phototrophs use light as their energy source, while chemotrophs use chemical reactions
    • Environmental factors like oxygen, temperature, pH, and osmolarity can affect bacterial growth and metabolism

    Microbiology

    • Microbiology is the study of organisms that are too small to be seen by the unaided eye
    • Microorganisms can be beneficial or harmful to humans
    • Microbiology involves the study of diseases caused by pathogens, and the control of these diseases through vaccination, antibiotics, and personal hygiene

    Three Domains of Life

    • The three domains of life are Eukaryota, Bacteria, and Archaea
    • Eukaryotes have one or more cells with a nucleus and well-developed intracellular compartments
    • Bacteria are prokaryotic microorganisms that are typically small and simple in structure
    • Archaea are prokaryotes that are similar to bacteria in size and simplicity, but have distinct molecular characteristics

    Cell Structure and Function

    • Cell membrane functions include barrier function, respiration/photosynthesis, and energy conservation
    • Cell wall determines and maintains the shape of the cell, and protects it from osmotic lysis
    • Gram-positive and Gram-negative cell walls have different structures and functions
    • Capsule, fimbriae, and pili are important structures involved in bacterial attachment and protection

    Bacterial Cytoplasm

    • Nucleoid is an irregularly shaped region that contains the genetic material
    • Plasmids are small, closed circular DNA molecules that exist and replicate independently of the chromosome
    • Cellular inclusions are granules of material that are reserved for future use
    • Endospores are highly resistant structures that can survive for long periods of time

    How Bacteria Cause Diseases

    • Most bacteria are harmless, and the host immune system prevents them from causing disease
    • Pathogens are organisms that cause diseases by impairing or interfering with normal physiological activities
    • Pathogenicity is the ability to cause disease, and virulence is the degree of pathogenicity
    • Infection and disease are different, with infection being the presence of a pathogen, and disease being the impairment of normal physiological activities

    Steps in Infectious Diseases

    • The steps in infectious diseases include the reservoir, transfer to host, colonization, adherence, and infection
    • The reservoir is where the bacterial pathogen lives and reproduces, and can be a human, animal, or environment
    • Transfer to host can occur through direct or indirect contact, or through vectors or vehicles

    Fungi

    • Fungi are eukaryotes that are extremely diverse, with cell walls made of chitin and polysaccharides
    • Fungi can be saprophytes, necrophytes, or biotrophs, and can reproduce both sexually and asexually
    • Fungi can be single-celled or multicellular, and can form colonies or mycelium
    • Yeasts are single-celled fungi that reproduce asexually by budding, while filamentous fungi are multicellular and reproduce by forming spores

    Cyanobacteria

    • Highly resistant to extreme conditions
    • Contain calcium dipicolinate, which binds free water and helps dehydrate the cell
    • Some cyanobacteria contain iron and have a special protein that protects their DNA, allowing them to orient themselves in magnetic fields

    Bacterial Nutrition and Growth

    • Nutrients provide elements for the synthesis of cell material
    • Macronutrients are required in large amounts and include elements like C, O, H, N, P, S, K, Ca, and Mg
    • Micronutrients are required in small amounts and include elements like Cu, Zn, Ni, V, and Se
    • Bacteria can grow in culture media, which provides all the necessary elements for growth
    • Culture media can be chemically defined, complex, or a nutrient agar plate
    • Bacteria can also grow in liquid media, such as Erlenmeyer flasks or test tubes

    Bacterial Growth Phases

    • Bacterial growth occurs in four phases: lag, log, stationary, and death
    • The lag phase is a period of slow growth, followed by the log phase, where growth is rapid and exponential
    • The stationary phase is where growth slows down due to resource depletion, and the death phase is where cell death occurs
    • Bacterial growth can be measured using direct microscopic count, culturable count, or serial dilution

    Metabolic Classification of Bacteria

    • Bacteria can be classified based on their carbon and energy resources
    • Heterotrophs use organic compounds as their carbon source, while autotrophs use CO2
    • Phototrophs use light as their energy source, while chemotrophs use chemical reactions
    • Environmental factors like oxygen, temperature, pH, and osmolarity can affect bacterial growth and metabolism

    Microbiology

    • Microbiology is the study of organisms that are too small to be seen by the unaided eye
    • Microorganisms can be beneficial or harmful to humans
    • Microbiology involves the study of diseases caused by pathogens, and the control of these diseases through vaccination, antibiotics, and personal hygiene

    Three Domains of Life

    • The three domains of life are Eukaryota, Bacteria, and Archaea
    • Eukaryotes have one or more cells with a nucleus and well-developed intracellular compartments
    • Bacteria are prokaryotic microorganisms that are typically small and simple in structure
    • Archaea are prokaryotes that are similar to bacteria in size and simplicity, but have distinct molecular characteristics

    Cell Structure and Function

    • Cell membrane functions include barrier function, respiration/photosynthesis, and energy conservation
    • Cell wall determines and maintains the shape of the cell, and protects it from osmotic lysis
    • Gram-positive and Gram-negative cell walls have different structures and functions
    • Capsule, fimbriae, and pili are important structures involved in bacterial attachment and protection

    Bacterial Cytoplasm

    • Nucleoid is an irregularly shaped region that contains the genetic material
    • Plasmids are small, closed circular DNA molecules that exist and replicate independently of the chromosome
    • Cellular inclusions are granules of material that are reserved for future use
    • Endospores are highly resistant structures that can survive for long periods of time

    How Bacteria Cause Diseases

    • Most bacteria are harmless, and the host immune system prevents them from causing disease
    • Pathogens are organisms that cause diseases by impairing or interfering with normal physiological activities
    • Pathogenicity is the ability to cause disease, and virulence is the degree of pathogenicity
    • Infection and disease are different, with infection being the presence of a pathogen, and disease being the impairment of normal physiological activities

    Steps in Infectious Diseases

    • The steps in infectious diseases include the reservoir, transfer to host, colonization, adherence, and infection
    • The reservoir is where the bacterial pathogen lives and reproduces, and can be a human, animal, or environment
    • Transfer to host can occur through direct or indirect contact, or through vectors or vehicles

    Fungi

    • Fungi are eukaryotes that are extremely diverse, with cell walls made of chitin and polysaccharides
    • Fungi can be saprophytes, necrophytes, or biotrophs, and can reproduce both sexually and asexually
    • Fungi can be single-celled or multicellular, and can form colonies or mycelium
    • Yeasts are single-celled fungi that reproduce asexually by budding, while filamentous fungi are multicellular and reproduce by forming spores

    Cyanobacteria

    • Highly resistant to extreme conditions
    • Contain calcium dipicolinate, which binds free water and helps dehydrate the cell
    • Some cyanobacteria contain iron and have a special protein that protects their DNA, allowing them to orient themselves in magnetic fields

    Bacterial Nutrition and Growth

    • Nutrients provide elements for the synthesis of cell material
    • Macronutrients are required in large amounts and include elements like C, O, H, N, P, S, K, Ca, and Mg
    • Micronutrients are required in small amounts and include elements like Cu, Zn, Ni, V, and Se
    • Bacteria can grow in culture media, which provides all the necessary elements for growth
    • Culture media can be chemically defined, complex, or a nutrient agar plate
    • Bacteria can also grow in liquid media, such as Erlenmeyer flasks or test tubes

    Bacterial Growth Phases

    • Bacterial growth occurs in four phases: lag, log, stationary, and death
    • The lag phase is a period of slow growth, followed by the log phase, where growth is rapid and exponential
    • The stationary phase is where growth slows down due to resource depletion, and the death phase is where cell death occurs
    • Bacterial growth can be measured using direct microscopic count, culturable count, or serial dilution

    Metabolic Classification of Bacteria

    • Bacteria can be classified based on their carbon and energy resources
    • Heterotrophs use organic compounds as their carbon source, while autotrophs use CO2
    • Phototrophs use light as their energy source, while chemotrophs use chemical reactions
    • Environmental factors like oxygen, temperature, pH, and osmolarity can affect bacterial growth and metabolism

    Microbiology

    • Microbiology is the study of organisms that are too small to be seen by the unaided eye
    • Microorganisms can be beneficial or harmful to humans
    • Microbiology involves the study of diseases caused by pathogens, and the control of these diseases through vaccination, antibiotics, and personal hygiene

    Three Domains of Life

    • The three domains of life are Eukaryota, Bacteria, and Archaea
    • Eukaryotes have one or more cells with a nucleus and well-developed intracellular compartments
    • Bacteria are prokaryotic microorganisms that are typically small and simple in structure
    • Archaea are prokaryotes that are similar to bacteria in size and simplicity, but have distinct molecular characteristics

    Cell Structure and Function

    • Cell membrane functions include barrier function, respiration/photosynthesis, and energy conservation
    • Cell wall determines and maintains the shape of the cell, and protects it from osmotic lysis
    • Gram-positive and Gram-negative cell walls have different structures and functions
    • Capsule, fimbriae, and pili are important structures involved in bacterial attachment and protection

    Bacterial Cytoplasm

    • Nucleoid is an irregularly shaped region that contains the genetic material
    • Plasmids are small, closed circular DNA molecules that exist and replicate independently of the chromosome
    • Cellular inclusions are granules of material that are reserved for future use
    • Endospores are highly resistant structures that can survive for long periods of time

    How Bacteria Cause Diseases

    • Most bacteria are harmless, and the host immune system prevents them from causing disease
    • Pathogens are organisms that cause diseases by impairing or interfering with normal physiological activities
    • Pathogenicity is the ability to cause disease, and virulence is the degree of pathogenicity
    • Infection and disease are different, with infection being the presence of a pathogen, and disease being the impairment of normal physiological activities

    Steps in Infectious Diseases

    • The steps in infectious diseases include the reservoir, transfer to host, colonization, adherence, and infection
    • The reservoir is where the bacterial pathogen lives and reproduces, and can be a human, animal, or environment
    • Transfer to host can occur through direct or indirect contact, or through vectors or vehicles

    Fungi

    • Fungi are eukaryotes that are extremely diverse, with cell walls made of chitin and polysaccharides
    • Fungi can be saprophytes, necrophytes, or biotrophs, and can reproduce both sexually and asexually
    • Fungi can be single-celled or multicellular, and can form colonies or mycelium
    • Yeasts are single-celled fungi that reproduce asexually by budding, while filamentous fungi are multicellular and reproduce by forming spores

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    Description

    This quiz covers the different stages of the life cycle of bacteriophages, including adsorption, penetration, replication, maturation, and release. It also explores the differences between lytic and lysogenic bacteriophages.

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