Podcast
Questions and Answers
What is the major function of MHC?
What is the major function of MHC?
- To produce antibodies against foreign antigens
- To regulate blood sugar levels
- To bind to processed antigen peptides and initiate an immune response (correct)
- To eliminate bacteria from the body
Which cells express MHC class II molecules?
Which cells express MHC class II molecules?
- Red blood cells
- T lymphocytes
- Dendritic cells, Macrophages, B lymphocytes (correct)
- All cell types
How many major classes of membrane-bound glycoproteins are encoded by MHC?
How many major classes of membrane-bound glycoproteins are encoded by MHC?
- Four
- One
- Two (correct)
- Three
What does MHC stand for?
What does MHC stand for?
Which cells recognize MHC class I molecules?
Which cells recognize MHC class I molecules?
What is the human equivalent of the Major Histocompatibility Complex?
What is the human equivalent of the Major Histocompatibility Complex?
What is the main function of MHC class I?
What is the main function of MHC class I?
Which cells function as antigen presenting cells (APC)?
Which cells function as antigen presenting cells (APC)?
What is the process of antigen presentation?
What is the process of antigen presentation?
Where are endogenous antigens degraded into peptides?
Where are endogenous antigens degraded into peptides?
What is the role of transporters associated with antigen processing (TAP) molecules?
What is the role of transporters associated with antigen processing (TAP) molecules?
Which molecules release CLIP from the MHC molecule during antigen presentation?
Which molecules release CLIP from the MHC molecule during antigen presentation?
What is the function of HLA class II?
What is the function of HLA class II?
What happens to exogenous antigens within the cell?
What happens to exogenous antigens within the cell?
Which process involves cells moving from the blood vasculature to peripheral tissues?
Which process involves cells moving from the blood vasculature to peripheral tissues?
Which cell surface polypeptides ensure appropriate cell-cell interactions?
Which cell surface polypeptides ensure appropriate cell-cell interactions?
What binds to CD34 and Glycam-1 (mucin-like) on endothelial cells?
What binds to CD34 and Glycam-1 (mucin-like) on endothelial cells?
Which molecules contain immunoglobulin-like domains and are expressed on endothelial cells?
Which molecules contain immunoglobulin-like domains and are expressed on endothelial cells?
What are the examples of Integrins that bind to Ig-superfamily CAMs?
What are the examples of Integrins that bind to Ig-superfamily CAMs?
Which group of proteins bind selectins and are rich in serine and threonine?
Which group of proteins bind selectins and are rich in serine and threonine?
What is the process where leukocytes settle-out of the central flow column and 'marginate' along the endothelial surface?
What is the process where leukocytes settle-out of the central flow column and 'marginate' along the endothelial surface?
What is the name of the complementary surface adhesion molecules briefly sticking and releasing, causing leukocyte tethering then rolling along the endothelium?
What is the name of the complementary surface adhesion molecules briefly sticking and releasing, causing leukocyte tethering then rolling along the endothelium?
What is the speed of tethering for leukocytes?
What is the speed of tethering for leukocytes?
Which molecules participate in the adhesion by conformational changes to the integrin, allowing firm binding to Ig superfamily CAMs?
Which molecules participate in the adhesion by conformational changes to the integrin, allowing firm binding to Ig superfamily CAMs?
During transmigration, cells must flatten and cross the endothelium basement membrane via:
During transmigration, cells must flatten and cross the endothelium basement membrane via:
What do leukocytes migrate towards by following a chemical gradient (chemokine) to the site of injury?
What do leukocytes migrate towards by following a chemical gradient (chemokine) to the site of injury?
What is the first step in lymphocyte migration?
What is the first step in lymphocyte migration?
Which molecules can cause chemotaxis for leukocytes?
Which molecules can cause chemotaxis for leukocytes?
What is shed during the rolling phase?
What is shed during the rolling phase?
What speed does rolling occur at?
What speed does rolling occur at?
