Podcast
Questions and Answers
Which of the following is true about leukemia treatment options?
Which of the following is true about leukemia treatment options?
- Leukemia treatment options are usually systemic. (correct)
- Leukemia treatment options are usually limited.
- Leukemia treatment options are usually localized.
- Leukemia treatment options are usually unknown.
What is the main characteristic of acute leukemia?
What is the main characteristic of acute leukemia?
- A preponderance of mature cells.
- A gap in the maturation process in bone marrow. (correct)
- A known cause of malignancy.
- A localized spread of abnormal cells.
How are leukemias grouped?
How are leukemias grouped?
- By treatment options and prognosis.
- By laboratory evaluation and pathologist role.
- By etiology and clinical presentations.
- By cell lineage and maturity of affected cells. (correct)
Which type of therapy uses monoclonal antibodies to bind directly to affected cells and activate cell lysis?
Which type of therapy uses monoclonal antibodies to bind directly to affected cells and activate cell lysis?
What is the most serious transplant complication in stem cell transplantation?
What is the most serious transplant complication in stem cell transplantation?
What is the primary cause of death in leukemia?
What is the primary cause of death in leukemia?
Which type of leukemia is also known as Acute Nonlymphocytic Leukemia (ANLL)?
Which type of leukemia is also known as Acute Nonlymphocytic Leukemia (ANLL)?
Which of the following is NOT a possible cause of malignancy according to the text?
Which of the following is NOT a possible cause of malignancy according to the text?
What is the minimum percentage of blasts in bone marrow required for an acute diagnosis in the FAB system?
What is the minimum percentage of blasts in bone marrow required for an acute diagnosis in the FAB system?
Which stage of therapeutic strategy involves low dose chemotherapy to prevent recurrence?
Which stage of therapeutic strategy involves low dose chemotherapy to prevent recurrence?
Which classification system was developed in 1976 to provide uniform criteria for classifying acute leukemias before treatment changed their cellular morphology?
Which classification system was developed in 1976 to provide uniform criteria for classifying acute leukemias before treatment changed their cellular morphology?
Which methodology for identifying and classifying leukemias involves the microscopic analysis of whole chromosomes?
Which methodology for identifying and classifying leukemias involves the microscopic analysis of whole chromosomes?
Which methodology for identifying and classifying leukemias involves the use of fluorescent antibodies to identify specific cell lineage and/or specific maturation stage markers?
Which methodology for identifying and classifying leukemias involves the use of fluorescent antibodies to identify specific cell lineage and/or specific maturation stage markers?
What is the main purpose of supportive therapy in cancer treatment?
What is the main purpose of supportive therapy in cancer treatment?
What is the most rare and desired type of bone marrow or stem cell transplant donor?
What is the most rare and desired type of bone marrow or stem cell transplant donor?
What are the common clinical symptoms of all leukemias?
What are the common clinical symptoms of all leukemias?
What is the difference between leukemoid reaction and leukoerythroblastic reaction?
What is the difference between leukemoid reaction and leukoerythroblastic reaction?
What is the historical method used to differentiate leukemoid reaction from leukemia?
What is the historical method used to differentiate leukemoid reaction from leukemia?
What is the normal range for Leukocyte Alkaline Phosphatase (LAP) scores?
What is the normal range for Leukocyte Alkaline Phosphatase (LAP) scores?
What is the current method used to identify chronic myeloid leukemia (CML)?
What is the current method used to identify chronic myeloid leukemia (CML)?
Match disorders with related leukemias.
Match disorders with related leukemias.
Match CDs with related leukemias.
Match CDs with related leukemias.
Gold standard for AMoL.
Gold standard for AMoL.
Which of the following is NOT a reason for performing a bone marrow evaluation?
Which of the following is NOT a reason for performing a bone marrow evaluation?
Which of the following is NOT a finding used to verify that bone marrow has been obtained during a bone marrow tap?
Which of the following is NOT a finding used to verify that bone marrow has been obtained during a bone marrow tap?
Which cell line is the most abundant in adult bone marrow?
Which cell line is the most abundant in adult bone marrow?
Which of the following is the correct order of preference for the preferred locations for a bone marrow tap?
Which of the following is the correct order of preference for the preferred locations for a bone marrow tap?
What is the normal range for the M:E ratio in adults?
What is the normal range for the M:E ratio in adults?
Which cytochemical stain is best used for differentiating between acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL)?
Which cytochemical stain is best used for differentiating between acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL)?
Which cytochemical stain is used to identify T-cell subsets of ALL and lymphomas?
Which cytochemical stain is used to identify T-cell subsets of ALL and lymphomas?
Which cytochemical stain is used to diagnose Hairy Cell Leukemia (HCL)?
Which cytochemical stain is used to diagnose Hairy Cell Leukemia (HCL)?
Which cytochemical stain is used to differentiate early CML from other conditions like leukemoid reaction or PV?
Which cytochemical stain is used to differentiate early CML from other conditions like leukemoid reaction or PV?
Which cytochemical stain stains glycogen and is positive in 80% of ALL cases?
Which cytochemical stain stains glycogen and is positive in 80% of ALL cases?
Which cytochemical stain is used to evaluate RBC iron stores?
Which cytochemical stain is used to evaluate RBC iron stores?
Which cytochemical stain is positive in granulocytes and monocytes?
Which cytochemical stain is positive in granulocytes and monocytes?
Which of the following is NOT a characteristic peripheral blood finding for Acute Lymphocytic Leukemia (ALL)?
Which of the following is NOT a characteristic peripheral blood finding for Acute Lymphocytic Leukemia (ALL)?
Which of the following is NOT a current treatment option for Chronic Lymphocytic Leukemia (CLL)?
Which of the following is NOT a current treatment option for Chronic Lymphocytic Leukemia (CLL)?
Which of the following is NOT a clinical feature of Chronic Lymphocytic Leukemia (CLL)?
Which of the following is NOT a clinical feature of Chronic Lymphocytic Leukemia (CLL)?
Which of the following is NOT a chronic leukemia that can be evaluated through peripheral blood and bone marrow findings?
Which of the following is NOT a chronic leukemia that can be evaluated through peripheral blood and bone marrow findings?
What is the current belief regarding the cause of Acute Leukemia?
What is the current belief regarding the cause of Acute Leukemia?
What is the main characteristic of Acute Leukemia?
What is the main characteristic of Acute Leukemia?
Which of the following is NOT a current diagnostic criteria for Acute Lymphocytic Leukemia (ALL)?
Which of the following is NOT a current diagnostic criteria for Acute Lymphocytic Leukemia (ALL)?
Which of the following is NOT a current diagnostic criteria for Chronic Lymphocytic Leukemia (CLL)?
Which of the following is NOT a current diagnostic criteria for Chronic Lymphocytic Leukemia (CLL)?
Which of the following is NOT a current treatment option for Acute Leukemia?
Which of the following is NOT a current treatment option for Acute Leukemia?
Which of the following is NOT a current treatment option for Acute Lymphocytic Leukemia (ALL)?
Which of the following is NOT a current treatment option for Acute Lymphocytic Leukemia (ALL)?
Which type of leukemia is characterized by the presence of >55% prolymphocytes in the peripheral blood?
Which type of leukemia is characterized by the presence of >55% prolymphocytes in the peripheral blood?
Which of the following is a characteristic finding in Prolymphocytic Leukemia (PLL)?
Which of the following is a characteristic finding in Prolymphocytic Leukemia (PLL)?
Which of the following is a characteristic finding in Hairy Cell Leukemia (HCL)?
Which of the following is a characteristic finding in Hairy Cell Leukemia (HCL)?
Which of the following is a characteristic finding in Hairy Cell Leukemia (HCL) on bone marrow aspiration?
Which of the following is a characteristic finding in Hairy Cell Leukemia (HCL) on bone marrow aspiration?
Which of the following is a clinical symptom commonly seen in Hairy Cell Leukemia (HCL)?
Which of the following is a clinical symptom commonly seen in Hairy Cell Leukemia (HCL)?
Which of the following is a lab finding in Hairy Cell Leukemia (HCL)?
Which of the following is a lab finding in Hairy Cell Leukemia (HCL)?
Which of the following is a characteristic finding in Prolymphocytic Leukemia (PLL) on bone marrow aspiration?
Which of the following is a characteristic finding in Prolymphocytic Leukemia (PLL) on bone marrow aspiration?
Which of the following is a clinical symptom commonly seen in Prolymphocytic Leukemia (PLL)?
Which of the following is a clinical symptom commonly seen in Prolymphocytic Leukemia (PLL)?
Which of the following is NOT a lab finding in Prolymphocytic Leukemia (PLL)?
Which of the following is NOT a lab finding in Prolymphocytic Leukemia (PLL)?
Which leukemia subtype accounts for 75% of childhood leukemias?
Which leukemia subtype accounts for 75% of childhood leukemias?
Which subtype of ALL is characterized by the presence of CD34, CD19, cytoplasmic CD22 (cCD22), and TdT markers?
Which subtype of ALL is characterized by the presence of CD34, CD19, cytoplasmic CD22 (cCD22), and TdT markers?
Which genetic mutation is most commonly found in T-cell ALL?
Which genetic mutation is most commonly found in T-cell ALL?
Which genetic mutation is associated with the worst prognosis in B-ALL?
Which genetic mutation is associated with the worst prognosis in B-ALL?
Which type of ALL is more common in adult and late teen males and frequently presents with mediastinal mass (thymomegaly)?
Which type of ALL is more common in adult and late teen males and frequently presents with mediastinal mass (thymomegaly)?
Which leukemia/lymphoma is the most common in the Western Hemisphere?
Which leukemia/lymphoma is the most common in the Western Hemisphere?
Which leukemia/lymphoma is characterized by the presence of CD5, CD19, CD20, CD23, IgM, and IgD+ B-cells?
Which leukemia/lymphoma is characterized by the presence of CD5, CD19, CD20, CD23, IgM, and IgD+ B-cells?
Which leukemia/lymphoma is diagnosed based on monoclonal B-lymphocytes greater than 5,000/uL in peripheral blood?
Which leukemia/lymphoma is diagnosed based on monoclonal B-lymphocytes greater than 5,000/uL in peripheral blood?
Which leukemia/lymphoma has an indolent course and is often managed with a 'watchful waiting' approach?
Which leukemia/lymphoma has an indolent course and is often managed with a 'watchful waiting' approach?
