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Questions and Answers
Which of the following is a characteristic of leukemia?
Which of the following is a characteristic of leukemia?
- Increased production of platelets
- Unregulated proliferation of blood-forming cells in the bone marrow (correct)
- Decreased production of red blood cells
- Infiltration of lymph nodes and skin by leukemia cells
What are the consequences of leukemia on bone marrow?
What are the consequences of leukemia on bone marrow?
- Increased production of red blood cells
- Enhanced production of neutrophils
- Inhibition of normal cellular maturation (correct)
- Decreased production of platelets
Where can leukemia cells infiltrate in the body?
Where can leukemia cells infiltrate in the body?
- Eyes, ears, nose, and throat
- Lymph nodes, skin, liver, spleen, kidney, testes, and the central nervous system (CNS) (correct)
- Muscles, bones, and joints
- Lungs, heart, stomach, and intestines
What is leukemia?
What is leukemia?
How is leukemia classified?
How is leukemia classified?
Flashcards
What is leukemia?
What is leukemia?
A type of cancer that affects blood-forming cells in the bone marrow.
Unregulated proliferation
Unregulated proliferation
The uncontrolled growth of blood-forming cells in the bone marrow.
Where can leukemia cells infiltrate?
Where can leukemia cells infiltrate?
Leukemia cells can spread to other parts of the body, including lymph nodes, skin, liver, spleen, kidney, testes, and the central nervous system.
How does leukemia affect the bone marrow?
How does leukemia affect the bone marrow?
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How is leukemia classified?
How is leukemia classified?
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Study Notes
Characteristics of Leukemia
- Leukemia is a type of cancer that affects the blood and bone marrow.
- It is characterized by the rapid production of abnormal white blood cells, which interfere with the body's ability to fight infections.
Consequences on Bone Marrow
- Leukemia disrupts normal blood cell production in the bone marrow.
- This can lead to reduced numbers of red blood cells, resulting in anemia.
- There is also a decrease in healthy white blood cells, increasing the risk of infections.
- Platelet production is affected, leading to bleeding and bruising.
Infiltration of Leukemia Cells
- Leukemia cells can infiltrate various organs and tissues, including the liver, spleen, lymph nodes, and central nervous system.
- Extramedullary sites can also be affected, leading to symptoms related to those organs.
Definition of Leukemia
- A cancer of the blood-forming tissues, predominantly affecting bone marrow and lymphatic system.
- It leads to the overproduction of immature or dysfunctional white blood cells.
Classification of Leukemia
- Leukemia is classified into four main types:
- Acute Lymphoblastic Leukemia (ALL)
- Acute Myeloid Leukemia (AML)
- Chronic Lymphocytic Leukemia (CLL)
- Chronic Myeloid Leukemia (CML)
- The classification is based on the speed of progression (acute vs. chronic) and the type of white blood cell affected (lymphoblastic vs. myeloid).
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