Leberfunktionen und klinische Kenngrößen

<p>Methode nach Jendrassik &amp; Grof (C)</p> Signup and view all the answers

<p>Eisen (C)</p> Signup and view all the answers

<p>Cholesterin (C)</p> Signup and view all the answers

<p>Geografische Lage (B)</p> Signup and view all the answers

<p>Vitamin D-Synthese (B)</p> Signup and view all the answers

<p>γ-Glutamyltransferase (D)</p> Signup and view all the answers

<p>Leberparenchymschäden (A)</p> Signup and view all the answers

<p>Hämolyse (A)</p> Signup and view all the answers

<p>ALP (B)</p> Signup and view all the answers

<p>&lt; 61 U/l (D)</p> Signup and view all the answers

<p>LAP (A)</p> Signup and view all the answers

<p>γ-Glutamyl-3-carboxy-4-nitroanilid (D)</p> Signup and view all the answers

<p>GGT (C)</p> Signup and view all the answers

<p>Es wird aus Albuminverbindung gelöst. (D)</p> Signup and view all the answers

<p>Lebererkrankung (D)</p> Signup and view all the answers

<p>Blau (B)</p> Signup and view all the answers

<p>Kinetische Enzymaktivitätsmessung (C)</p> Signup and view all the answers

<p>Gesamt-Bilirubin - Direktes Bilirubin (B)</p> Signup and view all the answers

<p>Indirektes Bilirubin ist erhöht. (A)</p> Signup and view all the answers

<p>Hepatischer Ikterus (B)</p> Signup and view all the answers

<p>Direktes Bilirubin ist stark erhöht. (A)</p> Signup and view all the answers

<p>Erhöhtes direktes Bilirubin (A)</p> Signup and view all the answers

<p>&lt; 1,20 mg/dl (B)</p> Signup and view all the answers

<p>Es ist erhöht. (D)</p> Signup and view all the answers

<p>Gesamt-Bilirubin kann erhöht sein. (B)</p> Signup and view all the answers

<p>Hepatozelluläre Nekrose (D)</p> Signup and view all the answers

<p>Kinetische Enzymaktivitätsmessung (C)</p> Signup and view all the answers

<p>&lt; 41 U/l (D)</p> Signup and view all the answers

<p>Schwerem Leberschaden (C)</p> Signup and view all the answers

<p>Erniedrigt bei Schwangerschaft (C)</p> Signup and view all the answers

<p>Medikamente (A)</p> Signup and view all the answers

<p>Im Gehirn, Muskulatur und Erythrozyten (B)</p> Signup and view all the answers

<p>GPT (D)</p> Signup and view all the answers

<p>Virushepatitis (B)</p> Signup and view all the answers

<p>Werte sind falsch hoch (A)</p> Signup and view all the answers

<p>&lt; 38 U/l (B)</p> Signup and view all the answers

<p>L-Aspartat (A)</p> Signup and view all the answers

<p>AS(A)T (A)</p> Signup and view all the answers

<p>MDH (B)</p> Signup and view all the answers

<p>L-Glutamat (A)</p> Signup and view all the answers

<p>Kinetische Enzymaktivitätsmessung (C)</p> Signup and view all the answers

<p>AST (B)</p> Signup and view all the answers

The liver is involved in carbohydrate, lipid, porphyrin, protein, amino acid, and nitrogen metabolism. It also handles urea synthesis, uric acid and creatinine synthesis, detoxification, and storage.

Clinical chemistry tests for liver function assess damage, metabolic issues, blockage (cholestasis), and scarring (fibrosis) using markers like GOT/AST, GPT/ALT, GLDH, Bilirubin, Alkaline phosphatase, Gamma-glutamyl transferase (GGT), Ammonia (NH3), Albumin, and clotting factors.

A yellow pigment produced from hemoglobin breakdown. High levels can indicate liver problems.

Bilirubin is detected using UV light. Interference factors like hemolysis (red blood cell breakdown) and lipemia (high fats) can alter the results.

Factors affecting bilirubin tests before analysis that might produce unreliable results (e.g., hemolysis and lipemia).

Part of the bilirubin that can be measured directly, and is important in differentiating bilirubin types and detecting liver issues.

A specific method used to determine the levels of bilirubin in a sample for diagnosing liver function and related conditions.

Liver conditions that affect the normal metabolic functions of the organ, including the creation and use of energy within the liver.

The sum of all forms of bilirubin in the blood, including direct and indirect.

Unconjugated bilirubin, not yet processed by the liver.

Conjugated bilirubin, processed by the liver and ready for excretion.

A laboratory test used to measure the amount of bilirubin in the blood.

A reddish-colored compound formed when bilirubin reacts with a specific chemical (diazotized sulfanilamide).

Jaundice caused by excessive bilirubin production before reaching the liver.

Jaundice due to liver dysfunction, preventing proper bilirubin processing.

Jaundice caused by obstruction of bile ducts, impacting bilirubin excretion.

A substance produced from bilirubin breakdown; presence indicative of liver and bile duct health.

The normal range of expected bilirubin values, indicating proper liver function.

A liver and bile duct specific enzyme. Elevated levels signal liver damage, cholestasis, or alcohol/drug abuse.

A condition where bile flow is blocked, often causing high levels of GGT.

Determined using a kinetic enzyme activity measurement. A substrate is transformed into a yellow compound by GGT.

Serum/Plasma GGT levels below 61 U/L are typically considered normal.

An enzyme used to diagnose cholestasis; elevated LAP levels, along with ALP, usually indicates liver issues.

Enzyme. Elevated levels can signal either liver problems or bone conditions.

Blood breakdown that can lead to falsely low GGT values during testing.

Distinguishing between possible conditions, such as liver issues versus bone issues, by comparing enzyme levels.

A unique rise in ALP (alkaline phosphatase) levels, typically indicating a bone-related issue.

Damage to the functional tissue of the liver causing enzyme levels to rise.

Glutmat-Oxalacetat-Transaminase, a liver enzyme.

Aspartat-Aminotransferase (another name for GOT).

Glutamat-Pyruvat-Transaminase, a liver enzyme.

Alanin-Aminotransferase (another name for GPT).

Glutamat-Dehydrogenase, an enzyme found in the liver's nucleus.

High levels of AST/GOT indicate potential liver damage or heart/muscle problems.

Determines liver health by measuring the activity of enzymes.

The expected normal levels of AST/GOT in serum/plasma.

A type of measurement for liver enzymes based on speed/rate of reaction.

Red blood cell breakdown, affecting liver enzyme test results.

Increased levels of Alanine aminotransferase (ALT) or Aspartate aminotransferase (AST) indicate liver cell damage (hepato-cellular necrosis).

Measuring ALT/GPT involves a kinetic enzyme activity method.

Glutamate dehydrogenase is an enzyme involved in ammonia (NH3) elimination from the body.

High GLDH levels may indicate severe liver damage.

Cholinesterase is an enzyme primarily found in the brain, muscles, and red blood cells; the liver also produces a form.

Low levels of Cholinesterase (CHE) in the blood can indicate liver cirrhosis, poisoning, or genetic factors.

Factors like medication, pregnancy, and age influence CHE test results.