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Clinical Chemistry: Liver Functions

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39 Questions

What is one of the primary functions of the human liver?

Production of bile

Where is albumin primarily produced?

Liver

What is the primary function of the hepatic duct?

Transportation of bile to the gallbladder and duodenum

What is a unique feature of hepatocytes?

Contact with bile canaliculi and bile ducts

What is a characteristic of bilirubin?

Poorly soluble in water at physiologic pH

What happens to bilirubin during conjugation?

It becomes more soluble in water

What is bilirubin di-glucuronide?

A type of bilirubin that has two glucuronic acid molecules attached

What is the primary site of albumin production in the body?

Liver

What is the primary location of the urea cycle?

Liver

What is the primary cause of the yellow color of urine?

Presence of stercobilin

Which of the following is a detoxification marker of the liver?

Serum albumin

What is the primary reason for the brown color of stool?

Presence of stercobilin

What is the primary location where ammonia is transferred to?

Liver

What is the primary characteristic of post-hepatic jaundice?

High level of conjugated bilirubin

What is the primary cause of prehepatic jaundice?

Sickle cell anemia

What is the color of urobilinogen?

Colorless

What is the primary product of conjugated bilirubin conversion by normal GI bacterial flora?

Colorless Urobilinogen and a brown-colored Urobilin

What is the primary fate of amino nitrogen in protein catabolism?

Converted to urea

What is the product of pyruvate transamination in skeletal muscle in the glucose-alanine cycle?

Alanine

What is the product of the reaction between carbamoyl phosphate and ornithine in the urea cycle?

Citrulline

What are the primary functions of the liver?

All of the above

What is the characteristic of the globulin level in multiple myeloma?

Increases

What is the characteristic of plasma ammonia levels in severe hepatocellular disease?

Increases

What is the consequence of drinking too much alcohol over long periods of time?

Alcoholic liver disease

What is the most sensitive indicator of jaundice?

Yellowing of sclera

What is the cause of hepatic jaundice?

Impaired uptake, conjugation or excretion of bilirubin

What is the purpose of liver function tests?

To detect and diagnose liver disease

What is responsible for the brown color of feces?

Stercobilin

Which organ is responsible for producing albumin?

Liver

What is NOT a function of the liver?

Regulation of body temperature

Which vitamin is NOT related to the liver?

Vitamin C

What is the primary organ responsible for excreting 80% of the body's nitrogen as urea?

Liver

What is the byproduct of conjugated bilirubin produced by GI bacterial flora?

Stercobilin and urobilinogen

Where is ammonia transported to after protein catabolism?

Liver

What is the primary function of bile salts?

Breakdown fat

What is the indication of elevated serum alanine transaminase?

Hepatocytes damage

Which of the following is NOT a function of the liver?

Bone mineralization

What is the term for a liver disease that occurs when bile is reduced or blocked?

Cholestasis

What is the primary function of ALT and AST?

Indicating hepatocytes damage

A quiz on liver functions and liver function tests, covering topics like bile production, metabolization of fats and carbohydrates, and albumin production.

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