Layers of the Epidermis Overview

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What is the primary function of the Stratum corneum in the epidermis?

Modification of keratin content

Formation of cornified envelope and desquamation (correct)

Cellular division and renewal

Maintenance of epidermal homeostasis

Which layer of the epidermis contains cells with numerous cytoplasmic processes attached by desmosomes?

Stratum granulosum

Stratum corneum

Stratum spinosum (correct)

Stratum basale

In skin tissue renewal, what structures are responsible for cell-cell interactions?

Hemidesmosomes

Corneodesmosomes (correct)

Profilaggrin granules

Lamellar bodies

Which process is associated with tissue repair rather than tissue renewal in the skin?

Complete regeneration Signup and view all the answers

Which layer of the epidermis is primarily responsible for mitotically dividing small cuboidal stem cells?

Stratum basale Signup and view all the answers

What distinguishes the Stratum granulosum from other epidermal layers?

Presence of lamellar bodies and profilaggrin granules Signup and view all the answers

What is the renewal rate of hepatocytes?

1 year Signup and view all the answers

Which of the following cell types show very limited or almost no cellular turnover?

Neurons Signup and view all the answers

In tissue homeostasis, which cells have low cellular turnover except in cases of injury?

Lymphocytes Signup and view all the answers

Which tissue has a renewal rate of 5 days for its epithelium?

Small intestine Signup and view all the answers

What is the primary function of the dermis in the skin structure?

Providing mechanical strength Signup and view all the answers

Which of the following cells are exceptions and can undergo differentiated cell division?

Hepatocytes Signup and view all the answers

What is the key cellular event that occurs during re-epithelialization in skin wound healing?

Proliferation and migration of stem cells Signup and view all the answers

In which phase of skin wound healing do myofibroblasts play a significant role?

Remodeling Signup and view all the answers

Which type of renewal involves complete regeneration similar to that observed during development?

Tissue renewal Signup and view all the answers

What is the primary function of macrogphages in the skin wound healing process?

Removal of cellular debris and resolution of inflammation Signup and view all the answers

Which process leads to avascular and acellular wound with collagen type I deposition in skin wound healing?

Granulation tissue formation Signup and view all the answers

What is the primary function of myofibroblasts in skin wound healing?

Contraction to pull wound margins together Signup and view all the answers