Laxatives: Uses and Considerations

<p>By decreasing net absorption of fluid</p> Signup and view all the answers

<p>Osteomalacia</p> Signup and view all the answers

<p>Before surgeries and procedures requiring an empty colon</p> Signup and view all the answers

<p>Increase the activity of NO synthase and the biosynthesis of platelet-activating factor</p> Signup and view all the answers

<p>Absorb water and increase faecal bulk</p> Signup and view all the answers

<p>Increases stool weight and transit due to high lignin content</p> Signup and view all the answers

<p>Lead to intraluminal fluid and electrolyte accumulation and increased intestinal motility</p> Signup and view all the answers

<p>It increases stool bulk by attracting water</p> Signup and view all the answers

<pre><code>Lead to intraluminal fluid and electrolyte accumulation and increased intestinal motility </code></pre> Signup and view all the answers

<p>Produces short-chain fatty acids that are trophic for colonic epithelium</p> Signup and view all the answers

<p>Resist intestinal disaccharidase activity and produce short-chain fatty acids</p> Signup and view all the answers

<p>Increased bacterial mass due to fermentation</p> Signup and view all the answers

<p>Excessive loss of water and electrolytes, secondary aldosteronism, steatorrhea, protein-losing enteropathy with hypoalbuminemia, and osteomalacia due to excessive loss of calcium in the stool.</p> Signup and view all the answers

<p>Laxation refers to the evacuation of formed fecal material from the rectum, while catharsis or purgation is the evacuation of unformed, usually watery fecal material from the entire colon.</p> Signup and view all the answers

<p>Laxatives act by enhancing retention of intraluminal fluid through hydrophilic or osmotic mechanisms.</p> Signup and view all the answers

<p>The commonly used laxatives promote laxation by enhancing the retention of intraluminal fluid and altering motility.</p> Signup and view all the answers

<p>Laxatives are employed before surgical, radiological, and endoscopic procedures where an empty colon is desirable.</p> Signup and view all the answers

<p>Excessive loss of water and electrolytes, secondary aldosteronism, steatorrhea, protein-losing enteropathy with hypoalbuminemia, and osteomalacia due to excessive loss of calcium in the stool.</p> Signup and view all the answers

<p>They absorb water and increase faecal bulk.</p> Signup and view all the answers

<p>They stimulate the release of cholecystokinin, leading to intraluminal fluid and electrolyte accumulation, and increased intestinal motility.</p> Signup and view all the answers

<p>It is a phospholipid proinflammatory mediator that stimulates colonic secretion and GI motility.</p> Signup and view all the answers

<p>It produces short-chain fatty acids that are trophic for colonic epithelium and increases bacterial mass.</p> Signup and view all the answers

<p>It attracts water and increases stool bulk.</p> Signup and view all the answers

<p>They are hydrolyzed in the colon to short-chain fatty acids.</p> Signup and view all the answers

<p>They lead to intraluminal fluid and electrolyte accumulation and increased intestinal motility.</p> Signup and view all the answers

<p>It is most effective at increasing stool weight and transit.</p> Signup and view all the answers

<p>They are better absorbed than magnesium salts, hence higher doses are required for their cathartic effect.</p> Signup and view all the answers

<p>It leads to an increase in colonic bacterial mass.</p> Signup and view all the answers